You may be trying to access this site from a secured browser on the server. Please enable scripts and reload this page.
Turn on more accessible mode
Turn off more accessible mode
Skip Ribbon Commands
Skip to main content
Turn off Animations
Turn on Animations
Hepato-pancreato-biliary (HPB) Cancers
It looks like your browser does not have JavaScript enabled. Please turn on JavaScript and try again.
Appointment
Find a Condition or Treatment
Find a Doctor
Menu
MAIN
Back to Home
About Us
Corporate Profile
Newsroom
Visitors Information
Contact Us
Patient Care
Specialties & Services
Your Clinic Visit
Cancer Information & Patient Support
E-Services
Find a Doctor
Visitor Policy
Research & Innovation
Research Labs
Programmes
Facilities
Our Researchers
Clinical Trials
SingHealth Research
Education & Training
Overview
Professional Development
Division of Cancer Education
Events
SingHealth Academy
Careers
Sponsorship
Giving
Why Give
Get Involved
Your Gift at Work
Be Informed
Make a Gift
Our Campaign
Volunteer
Research Labs
Back to Home
Cellular & Molecular Research
Bek Chai Heah Laboratory of Cancer Genomics
Laboratory of Molecular Carcinogenesis
Laboratory of Molecular Endocrinology
Laboratory of Liver Cancer Functional Genomics
Laboratory of Cancer Signalling
Lymphoma Genomic Translational Research Laboratory
Laboratory of Molecular Oncology
Laboratory of Clinical Pharmacology
Medical Sciences
Laboratory of Cancer Epigenome
Cancer Therapeutics Research Laboratory
Laboratory of Cell Therapy and Cancer Vaccine
Tan Chin Tuan Lab of Optical Imaging and Photodynamic & Proton Therapy
Laboratory of Translational Research in Gastrointestinal Cancer
Laboratory of Genomic Medicine
Programme in Translational and Clinical Liver Research
Translational Cancer Biology Laboratory
Laboratory of Applied Human Genetics
Hematopoietic Stem Cell & Cellular Therapy Lab
Clinical Trials & Epidemiological Sciences
Clinical Trials Office
Biostatistics & Epidemiology Unit
NCCS Research Committee & Scientific Advisory Board
Research Divisions Organisation Chart
Programmes
Back to Home
Disease Focus
Research Themes
Joint Breast Cancer Registry
Asia-Pacific Hepatocellular Carcinoma Trials Group
The VICTORY Consortium
Facilities
Back to Home
Overview
Specialised Units
Shared Facilities
Shared Services
Our Researchers
Back to Home
Division of Medical Oncology
Division of Surgery & Surgical Oncology, SGH and NCCS
Division of Radiation Oncology
Division of Oncologic Imaging
Division of Supportive and Palliative Care
Cellular and Molecular Research
Division of Medical Sciences
Clinical Trials & Epidemiological Sciences
Research Biennial Book
Clinical Trials
Back to Home
About Clinical Trials
Current Clinical Trials
ECRU
About Clinical Trials & Epidemiological Sciences
Clinical Trials Office
Biostatistics and Epidemiology Unit
SingHealth Research
Home
to skip to the main content on a page
to skip to the main content on a page
About Us
Back to Home
Corporate Profile
Chief Executive Officer's Message
Vision & Mission
NCCS Leadership
Annual Report
Awards
Key Milestones
Whistle-blowing Policy
Newsroom
Press Releases
Check Fake News
Visitors Information
Contact Us
Patient Care
Back to Home
Specialties & Services
Goh Cheng Liang Proton Therapy Centre
Haematology
Medical Oncology
Surgery & Surgical Oncology, SGH and NCCS
Radiation Oncology
Oncologic Imaging
Supportive & Palliative Care
Comprehensive Liver Cancer Clinic
Cancer Genetics Service
Nursing
NCCS Oncology @ SKH
NCCS Oncology Clinic @ CGH
Department of Psychosocial Oncology
Cancer Education and Information
Your Clinic Visit
Charges & Payment
Book an Appointment
Financial Aid
Medicine
Pharmacy
Video Consultation
When seeing a doctor
Cancer Information & Patient Support
For Patients
For Caregivers
Publications
Patient Stories
E-Services
Make/Change/Cancel Appointment
Request for Medical Report
Feedback Form
Health Buddy App
Find a Doctor
Visitor Policy
Research & Innovation
Back to Home
Research Labs
Cellular & Molecular Research
Medical Sciences
Clinical Trials & Epidemiological Sciences
NCCS Research Committee & Scientific Advisory Board
Research Divisions Organisation Chart
Programmes
Disease Focus
Research Themes
Joint Breast Cancer Registry
Asia-Pacific Hepatocellular Carcinoma Trials Group
The VICTORY Consortium
Facilities
Overview
Specialised Units
Shared Facilities
Shared Services
Our Researchers
Division of Medical Oncology
Division of Surgery & Surgical Oncology, SGH and NCCS
Division of Radiation Oncology
Division of Oncologic Imaging
Division of Supportive and Palliative Care
Cellular and Molecular Research
Division of Medical Sciences
Clinical Trials & Epidemiological Sciences
Research Biennial Book
Clinical Trials
About Clinical Trials
Current Clinical Trials
ECRU
About Clinical Trials & Epidemiological Sciences
Clinical Trials Office
Biostatistics and Epidemiology Unit
SingHealth Research
Education & Training
Back to Home
Overview
Professional Development
Continuing Medical Education
Continuing Nursing Education
Continuing Pharmacist Education
Division of Cancer Education
Undergraduate Education Unit
Postgraduate Education Unit
Nursing & Allied Health Education Unit
Faculty Development & Support Education Unit
Primary Care Oncology Education Unit
Communications, Mentoring, Ethics and Professionalism Education Unit
Medical Humanities Education Unit
Events
SingHealth Academy
Careers
Back to Home
Sponsorship
Professional Conversion Programmes
Giving
Back to Home
Why Give
About Us
Funding Innovative Research
Preventing Cancer
Advancing Medical Education
Helping Our Patients
Furthering Donor Impact
How Your Gift Helps
Get Involved
Honouring Your Gift
Become a Corporate Donor
Leave Your Legacy
Fundraise for Us
Join a Special Event
Your Gift at Work
Stories of Hope
Researchers in Action
Support for Patients
Our Work in the Community
Training Future Experts
Be Informed
Our Publications
Financial Statements
Make a Gift
Our Campaign
Make More Survivors
Jeans For Genes
Women VS Cancer
BCAM 2022
LCAM 2022
Volunteer
Home
>
Research & Innovation
>
Our Researchers
>
Hepato pancreato biliary (HPB) Cancers
Hepato-pancreato-biliary (HPB) Cancers
Facebook
WhatsApp
Email Us
share
Font Resize
A-
A
A+
Print
By:
Overview
Ongoing programs
Sarcoma, Peritoneal and Rare Tumours (SPRinT)
Breast Cancer
Hepato-pancreato-biliary (HPB) Cancers
Thoracic Surgery
Publications
Sign up today!
Page Content
DSSO hosts the multi-disciplinary Comprehensive Liver Cancer Clinic (CLCC) at NCCS comprising HPB surgeons, medical oncologists, radiation oncologist, nuclear medicine physicians, interventional radiologists, oncologic diagnostic radiologists, pathologists and nurse practitioners. The CLCC manages the whole spectrum of patients with HPB malignancies and multi-disciplinary case discussions are conducted twice a week. The HPB surgery team is heavily involved in clinically-driven cutting-edge translational and clinical studies that aim to interrogate the molecular and mechanistic basis of liver cancer, improve patient diagnosis and prognosis and develop novel therapies for HPB diseases by bringing discoveries from the bench to the bedside that can be translated to the next efficacious therapy.
The HPB discipline has vast experiences in conducting multicentre clinical trials and has spearheaded numerous investigator-initiated multicentre HCC clinical trials through the Program in Translational and Clinical Liver Cancer Research in NCCS led by Professor Pierce Chow. Nested within the program is the Secretariat of the Asia-Pacific Hepatocellular Carcinoma (AHCC) Trials Group which has completed 8 prospective, multi-centre clinical studies in HCC that has involved over 50 participating centres in 17 different countries and enrolled more than 3,000 patients. . The Group recently concluded the enrolment of a 2,500-patient from 33 sites, collecting real world data for the Asia-Pacific HCC Registry (AHCC08). Currently, the Group has begun recruitment for a prospective, cohort study involving 2,000 patients at high risk for HCC and a parallel cohort of 100 HCC patients across 6 specialist centres/hospitals and 8 polyclinics in Singapore (AHCC10 ELEGANCE and AHCC11 PROSECT). New clinical studies are in the pipeline and the group has established strong alliances with industries and pharmaceutical companies.
The Program also coordinates translational research platforms like the NMRC Flagship Translational and Clinical Research Program in Liver Cancer (AHCC07 PLANET) to conduct the world’s first prospective multi-national, multi-omics (genomics, immunomics, metabolomics) study in a surgically resected HCC cohort, the multi-institutional PuRPOSE Program to develop a patient-specific diagnostic and predictive platform to improve efficacy of HCC treatment. Most recently, the creation of a radiogenomics platform to accurately detect liver lesions and predict genomic driver mutations through standard-of-care imaging and AI-based predictive and diagnostic algorithms. We collaborate closely with leading research institutes, including the Genome Institute of Singapore (GIS), the Institute of Molecular and Cell Biology (IMCB), Singapore Phenome Centre (SPC), the Translational Immunology Institute (TII), Duke-NUS, Cancer Science Institute (CSI) and the Dept. of Biological Science, NUS, Singapore Bioimaging Consortium (SBIC), the Institute for Infocomm Research (I2R) and Samsung Medical Center, South Korea. These multi-institutional collaborations bring together different world-class scientific expertise to bear on the challenges of HCC.
More information on the AHCC Trials Group and all current/completed studies can be found
here
.
Sign up today!
10/18/2021 6:38 PM
×
SUBSCRIBE VIA EMAIL
Subscribe to our mailing list to get the updates to your email inbox...
Find a Doctor
Condition & Treatment
Home
Appointment
E-services