
Statistics from the latest Singapore Cancer Registry Annual Report 2023 show that breast cancer was the most common cancer in females, with approximately 1 in 12 women likely to develop the disease in their lifetime and close to 14,000 new cases diagnosed in Singapore between 2019 and 2023. Although it is more common in women, men can also be diagnosed with the disease.
The body normally repairs and replaces tissue through controlled cell growth. When this process becomes disrupted, cells may begin to grow and multiply abnormally. If these abnormal cells form a lump or mass, it is known as a tumour.
Not all tumours are cancerous:
Breast cancer occurs when cells in the breast mutate and grow in an uncontrolled way to form tumours. Most breast cancers begin in the ducts (the tubes that carry milk), while a smaller number start in the lobules (the glands that produce milk). Some tumours progress slowly, while others may grow more quickly.
Over time, breast cancer may spread to nearby lymph nodes or other areas such as the bones, liver, lungs or, less commonly, the brain. This is why identifying any symptom of breast cancer early and seeking medical evaluation promptly is important.

Early detection plays an important role in identifying breast changes or abnormalities early before symptoms develop, so that they can be assessed and treated promptly.
Breast screening includes breast self-examinations, clinical examinations and imaging tests. The type of screening recommended depends on an individual’s age, risk factors and medical history.

Being familiar with how your breasts normally look and feel can help you notice changes earlier. Breast Self-Examination (BSE) is a simple self-check that you can do at home once a month.
When to perform BSE
Seek medical advice if you notice changes such as redness, swelling, a lump, skin dimpling or nipple discharge.
A. Look for changes
Stand in front of a mirror and observe your breasts with your :
Check for:
B. Feel for changes while lying down
Women aged 40 and above are advised to have their breasts examined by a doctor or trained nurse once a year.
A CBE includes:
If any abnormalities are found, imaging tests may be recommended for further assessment.

A mammogram is a low-dose X-ray that allows specialists to view the internal structure of the breast. It is one of the most reliable methods for detecting early breast cancer, even when there is no visible lump.
What to expect
Who should consider mammograms?
Your doctor can advise the most suitable schedule based on your risk factors and medical history .
While not routinely used for general screening, these tests may be recommended for further evaluation or for women at higher risk:
These tests complement mammography but do not replace it for routine population cancer screening.
Breast cancer does not always cause symptoms in its early stages. Some conditions, such as ductal carcinoma in situ (DCIS), may only be detected during a routine screening mammogram. In some cases, DCIS may cause a small lump or blood-stained nipple discharge, but many women experience no noticeable signs.
For most people, early breast cancer is painless, and changes may be subtle. As the tumour grows, more recognisable symptoms can appear. Being familiar with the normal look and feel of your breasts can help you detect changes sooner.
Any symptom of breast cancer should be checked by a doctor promptly. Possible signs may include:
These symptoms do not always mean cancer, as many breast changes are due to benign conditions. However, any new or unusual symptom or change should be assessed by a doctor to ensure appropriate follow-up and peace of mind.

While there is no definitive way to prevent breast cancer, you can lower your risk by maintaining an active lifestyle, having a balanced diet and not smoking.
Women with a strong family history of breast cancer or those who carry certain genetic mutations (such as BRCA1 or BRCA2) may benefit from additional preventive measures, which can include:
For women at higher risk who choose not to pursue medication or breast surgery, closer monitoring is another option. Although this does not prevent breast cancer, it improves the chances of detecting changes early, when treatment is most effective.
A small percentage of breast cancersare caused by inherited genetic changes. The most recognised cause is a mutation in the BRCA1 or BRCA2 genes, which normally help to repair damaged DNA. When there is mutation of these genes, the risk of developing certain cancers, including breast and ovarian cancer, becomes significantly higher.
Individuals with these mutations may develop cancer at a younger age, face a higher likelihood of cancer affecting both breasts, and may have increased risk of developing more than one type of cancer across their lifetime. Other less common genetic mutations can also raise the risk of developing cancer .
HBOC syndrome can be passed from one generation to the next. Certain family patterns may suggest an inherited predisposition, including:
These features do not confirm a hereditary syndrome but indicate that further assessment may be helpful.
Diagnosis involves genetic testing, usually through a blood test that examines specific genes, including BRCA1 and BRCA2. Because test results have medical, emotional and familial implications, genetic testing is always accompanied by genetic counselling, both before and after testing, to ensure individuals fully understand the process and potential outcomes.
Testing is typically recommended only when established criteria suggest a meaningful likelihood of hereditary risk.
Genetic counselling is a structured, supportive process carried out by a trained genetic counsellor or cancer geneticist. The discussion helps individuals:
This approach ensures informed decision-making and provides ongoing support.
Anyone who notices a pattern of breast or ovarian cancers within their family is encouraged to speak with their doctor. A clinical review can help determine whether genetic risk assessment or testing is recommended.
A confirmed hereditary mutation can offer valuable insights, helping to:
This information supports families in making proactive, informed health decisions.
At NCCS, the Cancer Genetics Service (CGS) provides genetic counselling to individuals with a personal and/or family history of cancer. If you have a personal or family history suspicious for a hereditary cause, you may want to discuss this with your general practitioner (GP). Your doctor may refer you to Cancer Genetics Service to speak with a genetic counsellor.
The exact cause of breast cancer is not fully understood, but research has shown that several factors can increase a person’s likelihood of developing the disease. Having risk factors does not mean someone will get breast cancer, many people diagnosed have no obvious risk factors. However, understanding these influences can help guide screening, lifestyle choices and discussions with your healthcare team.
These are factors that individuals cannot alter:
These factors relate to lifestyle choices or external influences that individuals may be able to change:

Diagnosing breast cancer involves understanding both the type of cancer present and the extent of its spread.
Breast cancer is broadly classified in two ways:
Staging describes how advanced the cancer is at the time of diagnosis. Earlier stages generally have better treatment outcomes, while more advanced cancers may require multiple forms of therapy.
Staging considers:
Understanding Key Stages
Tumour biology examines the characteristics of the cancer cells, which can influence how the cancer behaves and treatment options. Key features include:
Tumour biology helps to determine the most appropriate breast cancer treatment, including suitability for hormonal therapy, targeted therapy or other systemic treatments.
If you notice a lump or any concerning changes in your breast, medical evaluation is essential. Diagnosis usually involves imaging tests followed by a biopsy to confirm the presence of cancer.
A biopsy is required to confirm a cancer diagnosis. It involves removing cells or tissue samples for laboratory examination.

Breast cancer treatment often involves a combination of therapies. The recommended approach depends on several factors, including:
Navigating treatment choices can feel overwhelming. Many patients find it helpful to attend consultations with a family member or friend to support discussions and decision-making.
Breast cancer treatment is broadly divided into local therapy and systemic therapy.
Local therapy targets cancer in the breast and nearby lymph nodes. It includes:
These treatments focus on the specific area affected by cancer.
Systemic therapy uses medications that travel throughout the body to treat cancer cells wherever they may be. These include:
Treatment sequencing
1. Surgery
Surgery for breast cancer has two main components:
(1) surgery to the breast and (2) surgery to assess or remove lymph nodes.
I. Surgery to the Breast
Breast-Conserving Surgery (BCS)
Oncoplastic Breast-Conserving Surgery
For some patients, additional techniques may be used to maintain breast shape and minimise deformity. These include:
Image-Guided Localisation
If the tumour cannot be felt, imaging guidance (mammogram, ultrasound or MRI) is used to place a wire or marker to show the surgeon exactly where to operate.
II. Mastectomy
Breast Reconstruction
Reconstruction can restore breast shape using flap reconstruction where tissue from the abdomen, back, thigh or buttock is used to form a new breast. Examples include:
This is major surgery, often requiring multiple drains and a longer hospital stay.
Implant-based reconstruction
Silicone implants may be placed either:
Nipple-Sparing and Skin-Sparing Approaches
In selected patients, the skin or nipple may be preserved if tissue sampling confirms no cancer involvement. If later results reveal cancer cells, a minor follow-up procedure may be required.
III. Axillary (Lymph Node) Surgery
Sentinel Lymph Node Biopsy (SLNB)
SLNB identifies the first lymph nodes that cancer is likely to spread to. A dye or radioactive tracer is used to guide the surgeon. If no cancer is found in these nodes, further lymph node surgery is usually unnecessary.
Axillary Clearance
If cancer is present in the nodes, a full removal of underarm lymph nodes may be recommended. Side effects may include:
Complications of Surgery
All surgery carries risks, including:
A breast care nurse typically provides guidance on post-surgery wound care, drains, exercises and recovery planning.
Radiation therapy uses high-energy X-rays to destroy cancer cells in a specific area of the body. It reduces the risk of cancer returning in the treated area and is often used alongside surgery.
Radiation Therapy may be advised:
How Radiation Therapy Works
Treatment is usually delivered daily, five days per week, over 1 to 6 weeks.
Side Effects
Early effects (during or shortly after treatment)
These usually improve within weeks.
Late effects (months or years later)
Your doctor will discuss individual risks.
Intraoperative Radiation Therapy (IORT)
IORT delivers a single, concentrated dose of radiation during surgery, immediately after tumour removal. It is suitable only for selected patients undergoing breast-conserving surgery.
Benefits
Possible side effects
1. Chemotherapy
Chemotherapy uses anti-cancer drugs to kill cancer cells throughout the body.
It may be given:
Treatment is delivered in cycles over three to six months.
Common side effects
Side effects are usually temporary and can be managed with supportive care.
In some cases of triple negative breast cancer, chemotherapy may be combined with immunotherapy, which activates the immune system to target cancer cells.
2. Targeted Therapy
Targeted therapies act on specific proteins or pathways in cancer cells. The most well-known example is HER2-targeted therapy (such as trastuzumab).
These drugs are used for HER2-positive cancers and have significantly improved outcomes.
Side effects
Other targeted drugs (e.g., lapatinib, bevacizumab) may be used depending on the cancer’s characteristics.
3. Hormonal Therapy
Hormonal therapy is used for hormone receptor-positive breast cancer, where cancer growth is influenced by oestrogen or progesterone.
Tamoxifen: Often recommended for premenopausal women.
Possible effects include:
Aromatase Inhibitors (AIs): Used mainly in postmenopausal women (e.g., anastrozole, letrozole, exemestane).
Possible effects include:
Newer hormonal and targeted agents (e.g., SERDs, CDK4/6 inhibitors) are increasingly used for specific patient groups.
Regular follow-up is essential after treatment. Appointments usually include:
Patients should report:
Recovering after breast cancer surgery involves caring for the wound, managing care of drainage tubes that remove fluids and pain management. Understanding what to expect can help patients feel more confident and supported during this stage.
Most surgical wounds are closed with absorbable stitches, so stitch removal is usually not required.
Patients are taught how to care for their wounds, including:
A soft, flexible drain may be placed under the skin to remove any fluid that collects after surgery. Patients who do not undergo breast reconstruction typically go home with the drain still in place.
Patients are shown:
The drain is removed in clinic once the fluid reduces, usually within one to two weeks.
Seek medical help if you notice:
Your doctor will advise on any medications to be taken. There are usually no special dietary restrictions post-surgery, although eating nutritious food supports recovery.
Patients are encouraged to return to light daily activities as soon as possible . Most individuals who undergo, breast-conserving surgery and simple mastectomy can resume their normal routine shortly after surgery .
Those who have breast reconstruction will receive specific instructions, as recovery may take longer and heavy lifting or certain movements may need to be avoided.
To prevent shoulder stiffness and improve arm mobility, patients will be taught arm exercises to do post-surgery.
Benefits include:
Exercises are done daily, with several repetitions of each movement. Strenuous activities should be avoided for the first few weeks after surgery.
After lymph node surgery, the risk of lymphoedema (arm swelling) increases. Extra care is needed to protect the arm from injury and infection.
Patients may be recommended the following for lymphoedema management:
Some patients choose breast reconstruction, while others prefer not to undergo further surgery. For those who decide against reconstruction, breast prostheses offer a way to restore shape and balance.
Breast Prostheses
Breast forms come in different shapes, sizes and skin tones. Some fit inside specially designed bras while others adhere directly to the skin.
A prosthesis:
A prosthesis fitting can be arranged around six weeks after surgery. Soft padding may be used in the early healing phase.
When choosing a breast form, selecting a size and weight similar to the natural breast helps prevent back or neck strain.
Breast cancer is the most frequently diagnosed cancer among women. In Singapore, more than a quarter of cancers affecting women are breast cancers, with over 2,500 new cases detected each year.
Most breast lumps, however, are not cancerous. Many are benign changes linked to natural hormonal cycles.
No. A bruise or injury does not cause cancer. Injury may lead to temporary scar tissue, which can look abnormal on imaging, but symptoms should ease within a few weeks. If symptoms persist, speak to your doctor.
The majority of breast lumps are benign. It is estimated that only one in ten breast lumps turn out to be cancer. Lumps become more concerning with age, so any changes should be assessed by a doctor.
Most benign lumps remain harmless. The key is to ensure that the breast lump is examined by a doctor and accurately diagnosed as benign.
Most benign issues do not recur, but some women may develop new benign breast lumps over time.
No single test is perfect, if you feel a lump that is not visible on mammography, your doctor may recommend further investigational tests such as ultrasound, MRI or a biopsy.
Early breast cancer is often highly treatable. Your doctor will discuss the diagnosis and explain the most appropriate treatment options.
If your symptoms are thought to be hormonal, you may wait until after your next period to reassess. If you are still concerned, you can return to your doctor for further checks or request a second medical opinion.
A strong family history may increase your risk, especially if close relatives were diagnosed at a young age. Speak with your doctor, who may refer you to a breast specialist or discuss genetic assessment.
Some treatments, including chemotherapy and hormonal therapy, may cause temporary or permanent changes to your menstrual cycle. Women nearing menopause may stop having periods altogether.
Pregnancy after treatment may be possible, but timing is important. Some doctors recommend waiting one to two years before conceiving. Always seek advice from your treating doctor before planning a pregnancy.
The decision depends on tumour size, breast size, cancer type and patient preference. Some women opt for mastectomy for cosmetic or medical reasons, particularly when reconstruction is planned.
Modern mammography uses very low radiation doses and is considered safe for regular screening.
Most breast lumps are benign. Seeing a doctor promptly will give you peace of mind and ensures treatment is started early, if needed.
A small proportion of breast cancers are inherited. Your risk depends on the number of affected relatives and their ages at diagnosis. Screening and guidance are available.
Many women treated for breast cancer go on to live long, healthy lives. Your doctor can advise on what to expect based on your diagnosis.
Not always. The type of surgery recommended depends on breast size, tumour size and tumour location. Breast-conserving surgery may be possible for many women.
Most side effects from chemotherapy and radiation therapy are temporary and can be managed by your clinical care team.
Some breast cancers grow in response to female hormones such as oestrogen. Hormonal therapy blocks or reduces these effects, helping to prevent recurrence.
Tamoxifen is a commonly used tablet that blocks the action of oestrogen. Other medicines may be prescribed depending on the tumour biology and menopausal status of the patient.
Possible effects include:
More serious complications such as blood clots or changes to the uterus lining are rare but require monitoring.
Only cancers with hormone receptors (oestrogen or progesterone receptors) respond to hormonal therapy.
Breast forms come in different shapes, sizes and skin tones. They are designed to match your natural breast and support posture and comfort.
Most prostheses can be gently washed and stored in their protective case when not in use.
Reconstruction recreates the shape of the removed breast using implants or your own tissue. It can be done during the mastectomy or later. Your surgeon will advise on suitable options.
Gentle activity, such as walking, is encouraged. Your care team will advise when to resume your exercise regime.
Yes. Regular mammograms of the remaining breast are important. You should also continue monthly self-checks.
You may breastfeed from the unaffected breast. Breastfeeding from the treated breast may be affected after mastectomy or radiation therapy.
A lumpectomy generally will not affect breastfeeding, although radiation therapy may reduce milk production. A biopsy does not affect your ability to breastfeed.
Arm exercises help to prevent shoulder stiffness, promote lymphatic flow to manage swelling and support the recovery of normal arm movement.
Your doctor will advise when you can start light exercise after surgery to restore strength and flexibility.