Dr Johnny Ong
Dr Chua Yang Chong
Dr Nicholas Shannon
Ng Wai Har
Tan Qiu Xuan
Dr Amit Jain
Dr Tan Ngian Chye
The Laboratory of Applied Human Genetics was conceived 3 years ago under theleadership of Prof. Teo and Asst. Prof. Ong. Asst. Prof. Ong pursued his PhD at the University of Cambridge, UK, as an NRF-MOH Research Scholar in 2009. As a returning scientist with an aspiration to become a surgeon–scientist, he quickly resumed cancer research and has been under the mentorship of Prof. Kon since 2016.
Our laboratory is an interdisciplinary laboratory, with a specific focus on peritoneal and sarcoma malignancies. The dual-hatting of surgeon–scientists in the Division of Surgical Oncology gives our laboratory an intrinsic advantage by combining our clinical practice with laboratory research, effectively paving the way for bench-to-bedside translational research. Our laboratory’s area of expertise harnesses this advantage, allowing for a) multi-sampling of surgically collected samples to correct for intra-tumoral heterogeneity, b) rapid transfer of tissues to prevent degradation, and c) generation of in vivo mouse models of human samples. Our approach to solving clinical questions with translational relevance and addressing hypotheses is illustrated in Figure 1.
Since its inception, our laboratory has been awarded seven grants, including two National Medical Research Council (NMRC) grants. The team has also receivednumerous awards, including International Conference Travel Award, Best OralPresentation Award, Young Investigator Award, Distinguished Young Researcher Award, and an NMRC Transition Award. Despite our infancy, we have onepublication with an impact factor >5 and two manuscripts currently under review.Our team’s present work is expected to be published in the next 18 months in a journal with an impact factor >10.
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11 Hospital Drive, Singapore 169610 +65 6436 8000