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Our Research

Title of Study Contact Investigator Status
PREoperative therapy and Supportive Care in EarLy & Locally Advanced breast cancers – PreSCella Dr Tira Tan Jing Ying  On-going 
Outcomes of Mucinous Breast Cancer

Dr Ryan Ying-Cong Tan

Male Breast Cancer: Clinical, histopathological, treatment  and outcomes Dr Joshua Lim Cheng Hao  On-going 
 Radiation induced cardiotoxicity in breast cancer patients  Dr Ng Wee Loon On-going 
Investigating the role and impact of discordant hormone receptor status in newly diagnosed breast cancer patients  Dr Grace Kusumawidjaja On-going 
Retrospective review of imaging findings and surveillance outcomes after oncoplastic breast conserving surgery Dr Lester Leong Chee Hao  On-going 

Effects of housing value and medical subsidy on treatment and outcomes of breast cancer patients in Singapore: A retrospective cohort study. The Lancet Regional Health - Western Pacific 6 (2021) 10 0 065. F.Y. Wong, R.X. Wong, S. Zhou et al.


 Dr Wong Fuh Yong Full text

Contrasting Epidemiology and Clinicopathology of Female Breast Cancer in Asians vs the US Population. J Natl Cancer Inst. 2019 Dec 1;111(12):1298-1306. Lin CH, Yap YS, Lee KH, Im SA, Naito Y, Yeo W, Ueno T, Kwong A, Li H, Huang SM, Leung R, Han W, Tan B, Hu FC, Huang CS, Cheng AL, Lu YS; Asian Breast Cancer Cooperative Group.                


Dr Yap Yoon Sim 

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The impact of radiotherapy and histological risk factors on outcomes in malignant phyllodes tumors. Clin Breast Cancer.  2020 Dec;20(6):e695-e700. Wong RX, Koh YS, Wong FY, Kusumawidjaja G, Ng WL, Yeo RMC, Farid M, Sheng, Chan JY, Yan Z, Gudi MA, Tan PH


Dr Wong Ru Xin Abstract

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Human epidermal growth factor receptor 2 positive rates in invasive lobular breast carcinoma: The Singapore experience. World J Clin Oncol 2020; 11(5): 283-293. Ga-Jing Kee, Ryan Ying-Cong Tan, Sultana Rehena, Joycelyn Jie-Xin Lee, Ma Wai-Wai Zaw, Wei-Xiang Lian, Joe Yeong, Su-Ming Tan, Swee-Ho Lim, Benita Kiat-Tee Tan, Yoon-Sim Yap, Rebecca Alexandra Dent, Fuh-Yong Wong, Guek-Eng Lee

  Dr Ryan Ying-Cong Tan Full text
Patterns of relapse after neoadjuvant chemotherapy in breast cancer: implications for surveillance in clinical practice. Breast Cancer Res Treat. 2019 Aug;177(1):197-206.  Saw S, Lim J, Lim SH, Wong M, Lim C, Yap YS
Dr Yap Yoon Sim


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Validation of Modified Breast Graded Prognostic Assessment for breast cancer patients with brain metastases: extra-cranial disease progression is an independent risk factor. Ann Palliat Med 2019;8(4):390-400. Qingyuan Zhuang, Ru Xin Wong, Wei Xiang Lian, You Quan Li, Fuh Yong Wong

 Dr Zhuang Qingyuan Full text

Breast cancer risk in neurofibromatosis type 1 is a function of the type of NF1 gene mutation: a new genotype-phenotype correlation. Ian M Frayling, Victor-Felix Mautner, Rick van Minkelen, Roope A Kallionpaa, Safiye Aktaş, Diana Baralle, Shay Ben-Shachar, Alison Callaway, Harriet Cox, Diana M Eccles, Salah Ferkal, Holly LaDuca, Conxi Lázaro, Mark T Rogers, Aaron J Stuenkel, Pia Summerour, Ali Varan, Yoon Sim Yap, Ouidad Zehou, Juha Peltonen, Gareth D Evans, Pierre Wolkenstein, Meena Upadhyaya


  Dr Yap Yoon Sim Full text

Gestational breast cancer in Singapore women. Proceedings of the 2018 San Antonio Breast Cancer Symposium; 2018 Dec 4-8; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2019;79(4 Suppl):Abstract nr P4-10-12. QT Tan, FY Wong, VS Alcantara, R Ganguly and KW-J LohIn

  Dr Tan Qing Ting  Abstract

Breast cancer anatomic staging with biological risk Score is effective and simple to use. Melbourne International Breast Conference Oct 2018. WX Lian, RX Wong, YH Seow, YS Yap, JHC Lim, FY Wong

  Dr Wong Ru Xin

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Validation of the AJCC 8th prognostic system for breast cancer in an Asian healthcare setting. Breast. 2018 Apr 17;40:38-44. Wong RX, Wong FY, Lim J, Lian WX, Yap YS
  Dr Wong Ru Xin


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Surgery for early breast cancer in the extremely elderly leads to improved outcomes - An Asian population study. Breast. 2017 Dec; 36:44-48. Lee CM, Zheng H, Tan VK, Tan TJ, Kanesvaran R, Wong FY, Sim YR, Yong WS, Madhukumar P, Ong KW, Tan BK

A/Prof Benita Tan Kiat Tee


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Screening uptake differences are not implicated in poorer breast cancer outcomes among Singaporean malay women. J Breast Cancer. 2017 Jun;20(2):183-191. Wong Ru Xin, Li-lian Kwok, Wong Fuh Yong

Dr Wong Ru Xin Full text

Outcome after neoadjuvant chemotherapy in Asian breast cancer patients. Cancer Med. 2017 Jan; 6(1): 173–185. Li Yan Lim, Hui Miao, Joline S.J.Lim, Soo Chin Lee, Nirmala Bhoo-Pathy, Cheng Har Yip, Nur Aishah B.M.Taib, Patrick Chan, Ern Yu Tan, Swe Ho Lim, Geok Hoon Lim, Evan Woo, Yia Swam Tan, Jung Ah Lee, Mabel Wong, Puay Hoon Tan, Kong Wee Ong, Fuh Yong Wong, Yoon Sim Yap, Mikael Hartman


 Dr Yap Yoon Sim Full text

Clinicopathological characteristics and treatment outcomes in patients with stage I-III invasive Lobular carcinoma of the breast (ILC) treated at the National Cancer Centre Singapore. 2016 ASCO Annual Meeting. J Clin Oncol 2016 suppl; abstr. Joycelyn Jie Xin Lee, Fuh-Yong Wong, Benita Tan, Swee Ho Lim, Sze Huey Tan, Joanne YY Ngeow, Rebecca Alexandra Dent


 Dr Joycelyn Jie Xin Lee  Abstract

Prognostic role of adjuvant radiotherapy in triple-negative breast cancer: A historical cohort study.Int J Cancer. 2015 Nov 15;137(10):2504-12. Bhoo-Pathy N, Verkooijen HM, Wong FY, Pignol JP, Kwong A, Tan EY, Aishah Taib N, Nei WL, Ho GF, Tan B, Chan P, Lee SC, Hartman M, Yip CH, Dent R

Dr Rebecca Alexandra Dent   Full text