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Drug Class: Commonly Known As: Category:
Alkylating Agent Temodal® Cancer-related

Temozolomide - What is it for

Temozolomide is a medicine that is used for the treatment of brain tumours.​​

Temozolomide - Side Effects, Precautions, and Contraindications

What side effects can Temozolomide cause?

  • Nausea and vomiting
    Your doctor may prescribe certain medicines to help prevent or manage this; take them accordingly as instructed. Where possible, taking Temozolomide at bedtime may also help to reduce nausea or vomiting.
  • Fatigue
  • Headache
  • Constipation
  • Decreased blood cells
    This may increase your chances of getting infections, bruising or bleeding and feeling tired.

Inform your doctor if any of the following occurs:

  • Fever of 38°C or higher, chills, cough, sore throat,
  • Unusual bruising, bleeding or black stools
  • Yellowing of the eyes or skin, dark tea-coloured urine and severe abdominal pain
  • Allergic reactions - hives or rashes, facial swelling, breathing difficulty

Before taking Temozolomide , what precautions must I follow?

  • Effective birth control measures are recommended for both men and women during and up to 6 months after treatment with Temozolomide. Inform your doctor if you plan to or suspect that you are pregnant.
  • Do not breastfeed. Inform your doctor if you intend to breastfeed.

What food or medicine must I avoid when I take Temozolomide ?

Temozolomide - Dosage and How to Use

How should Temozolomide be used?

Temozolomide is a capsule, to be taken by mouth at the same time of the day.
Take it on an empty stomach, at least one hour before food.

If your child is unable to swallow the capsule, you may open the capsule and dissolve the contents in apple juice or applesauce.

What should I do if I miss a dose?

​​If you miss a dose of Temozolomide, contact your doctor for further instructions on what to do.

What should I do if I overdose?

If you overdose on this medicine, inform your doctor immediately.

Temozolomide - Handling

How should I handle Temozolomide safely?

Do not crush or chew the capsules. 

Take precautions to avoid cytotoxic exposure: wear gloves and mask when handling the capsules, and open the capsules in a still-air room (if applicable)

Temozolomide - Storage

How should I store Temozolomide ?

;#Keep away from children;#Keep in a cool, dry place, away from direct sunlight;#Store at room temperature;#

How should I dispose of Temozolomide safely?

Temozolomide - Additional Information

  • Updated on 10/12/2017 12:00:00 AM
  • Article contributed by Department of Pharmacy National Cancer Centre Singapore
The information provided is not intended as medical advice. Terms of use. Information provided by SingHealth


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