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Fluoroquinolone​s

Drug Class: Commonly Known As: Category:
Fluoroquinolones Adult, Children

Fluoroquinolone​s - What is it for

​Fluoroquinolones belong to a class of antibiotic, and is used to treat infections.​

Fluoroquinolone​s - Side Effects, Precautions, and Contraindications

What side effects can Fluoroquinolone​s cause?

​Common side effects include:

  • Dizziness, insomnia, nervousness, drowsiness. If you experience these symptoms, do not drive or operate any machinery.
  • Gastrointestinal side effects including nausea, vomiting and abdominal pain. It is advisable to take the medication after food if you experience such side effects.
  • Your skin may also become more sensitive to sunlight or UV (ultraviolet light) while taking fluoroquinolones. Avoid exposure to strong sunlight (tanning) or artificial UV lights such as sunbed.

There are some potentially serious, but less common side effects that may be experienced. Seek medical advice immediately, even though you are no longer taking the drug if the side effects below occur.

  • Peripheral neuropathy typically presented as pain, burning, tingling, numbness, weakness or a change in sensation to light touch, pain or temperature. The onset of peripheral neuropathy after starting fluoroquinolones therapy is usually rapid and may persist for a few days.
  • Pain and swelling in the joints and tendinitis. The pain may present as early as the first 48 hours of taking the treatment or up to several months after end of treatment. At first sign of any pain and inflammation of joints, stop taking and rest the painful area.
  • Eyesight changes e.g. blur vision, sensation of flashing light, appearance of floaters.
  • Behavioural changes e.g. agitation, nervousness, disorientation, disturbances in attention, memory impairment and delirium.
  • Low blood sugar (hypoglycaemia), particularly in the elderly or those on diabetic medications, which may present as unusual hunger, weakness , sweating or trembling.

Stop the medication immediately if you experience any severe allergic reactions like skin rash, swelling of the eyes and lips or difficulty breathing.​​

Before taking Fluoroquinolone​s, what precautions must I follow?

​Inform your health care professional if you have history of epilepsy or conditions that predispose to seizures or glucose-6-phosphate dehydrogenase (G6PD) deficiency before starting the medication.

What food or medicine must I avoid when I take Fluoroquinolone​s?

Fluoroquinolone​s - Dosage and How to Use

How should Fluoroquinolone​s be used?

​Fluoroquinolones are prescribed by the doctor to treat infections. They are usually taken either once or twice a day.

Fluoroquinolones can be taken with or without food. Fluoroquinolones should be spaced at least 2 hours apart from antacids, calcium and iron-containing medications or food to avoid impairing the absorption of the medication.

What should I do if I miss a dose?

​If you miss the dose, take it as soon as you remember. However, if it is close to the next timing that you are supposed to take your next dose, skip the previous dose and take the next dose at your usual timing. Do not take double the dose.​

What should I do if I overdose?

Fluoroquinolone​s - Handling

How should I handle Fluoroquinolone​s safely?

Fluoroquinolone​s - Storage

How should I store Fluoroquinolone​s?

Keep away from children;#Keep in a cool, dry place, away from direct sunlight;#Store at room temperature;#

How should I dispose of Fluoroquinolone​s safely?

Fluoroquinolone​s - Additional Information

​Click here for more information on Fluoroquinolones used as Antibiotics. 

  • Tags: Levofloxacin, Ciprofloxacin
  • Updated on Thursday, January 25, 2018
  • Article contributed by Pharmacy Department KK Women's and Children's Hospital

    The information provided is not intended as medical advice. Terms of use. Information provided by SingHealth

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