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Dutasteride

Drug Class: Commonly Known As: Category:
5 Alpha Reductase Inhibitor Duodart

Dutasteride - What is it for

​It is used to treat benign prostatic hyperplasia (enlarged prostate), a non-cancerous growth of the prostate gland, caused by overproduction of a hormone called dihydrotestosterone. It lowers dihydrotestosterone, and thus shrinks the prostate and relieves the symptoms. Therefore, this medication is for use in men only. It may take up to 6 months or more for you to notice an effect. 

As the prostate enlarges, it can lead to urinary problems such as difficulty in passing urine and frequent visits to the toilet. It can also cause the flow of urine to be slower and weaker. If left untreated, there is a risk that the urine flow may be completely blocked (acute urinary retention) and this requires immediate medical treatment.

Dutasteride can be used alone or with another medication called Tamsulosin to treat enlarged prostate. 

This medication may also be used for other conditions. Check with your healthcare professional
if you are unsure why you are given this medication.

Dutasteride - Side Effects, Precautions, and Contraindications

What side effects can Dutasteride cause?

  • ​Unable to get or keep an erection firm enough to have sexual intercourse
  • Decreased libido (sex drive); less desire to have sex
  • Difficulty with ejaculation
  • Dizziness when taken in combination with tamsulosin

These side effects may disappear after a while if you continue to take the medication. If not, they usually go away after stopping the medication. Discuss with your doctor if you are unsure or these side effects become bothersome to you.

The symptoms of a drug allergy include one or more of the following:

  • Swollen face/eyes/lips/tongue
  • Difficulty in breathing
  • Itchy skin rashes over your whole body

Changes in your breast tissue such as lumps, pain, enlargement or nipple discharge.

If you experience any of these symptoms, you should stop your medication and see your healthcare professional immediately.

Before taking Dutasteride, what precautions must I follow?

  • ​Use a condom during sexual intercourse as your semen could contain the medication. If your partner is or may be pregnant, you must avoid exposing her to your semen as it may affect the normal development of the baby’s sex organs.
  • Avoid donating blood during treatment or for 6 months after you stopped the treatment as there may be a risk that your blood may be given to a pregnant female transfusion recipient.

Inform your healthcare professional if:

  • You are allergic to this medication or any of the other ingredients of this medication
  • You have heart or liver problem

What food or medicine must I avoid when I take Dutasteride?

​Inform your healthcare professional if you are taking or intend to take any other medication, supplements, traditional medications or herbal remedies.

Dutasteride - Dosage and How to Use

How should Dutasteride be used?

  • ​Do not stop taking your medication without checking with your healthcare professional.
  • You may take this medication with or without food.
  • This medication should be swallowed whole; do not chew or open as contact with the contents of the capsules may make your mouth or throat sore.
  • This medication should not be touched or handled by pregnant women or women who are of childbearing age as the active ingredient of the medication (Dutasteride) can be absorbed through the skin. If contact with a leaking capsule occurs, wash the area immediately with soap and water as the medication may negatively affect the development of the fetus.

What should I do if I miss a dose?

​If you forget to take a dose, take it as soon as you remember. Then take your next dose at the usual time. Do not take two doses to make up for the missed dose.

What should I do if I overdose?

Dutasteride - Handling

How should I handle Dutasteride safely?

Dutasteride - Storage

How should I store Dutasteride?

Keep away from children;#Keep in a cool, dry place, away from direct sunlight;#

​Keep away from pregnant women and women who are of childbearing age.

How should I dispose of Dutasteride safely?

​Pack this medication into a black trash bag and seal it tightly before throwing into the rubbish chute or bin.

Dutasteride - Additional Information

  • Updated on Monday, September 30, 2019
  • Article contributed by PSS National Medication Information Workgroup PSS National Medication Information Workgroup

    The information provided is not intended as medical advice. Terms of use. Information provided by SingHealth

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