Assoc Prof Dent’s primary research interest is in the field of breast cancer, focusing on locally advanced breast cancer and triple-negative breast cancers. She is principal investigator for several clinical trials for the treatment of preoperative and advanced breast cancer. She serves on a number of scientific committees at ASCO, ESMO and ESMO Asia.
Dr .Daniel Tan is a Senior Consultant with the Division of Medical Oncology at National Cancer Centre Singapore (NCCS) and a Clinician-Scientist Fellow at Genome Institute of Singapore. His main area of interest is in thoracic, head and neck malignancies. He currently leads the phase I unit (Experimental Cancer Treatment Unit, ECRU) where he is the principal investigator for multiple biomarker-driven early phase clinical trials including first-in-human studies.
One of the principal investigators heading the Cancer Therapeutics Research Laboratory at NCCS, Dr Tan’s current research interests include rational application of “omics” technologies to unravel drug resistance in cancer therapeutics and accelerating the development of novel agents and biomarkers in the clinic. His research has won multiple international awards, including European Society of Medical Oncology Congress Travel Award, American Society of Clinical Oncology (ASCO) Merit Awards and an ASCO Young Investigator Award. Recent awards include the SingHealth Publish! Award (Medical Research) and SingHealth GCEO Outstanding Clinician – Researcher Award.
Dr. Tan has served on the International Association for Study of Lung Cancer (IASLC) education committee since 2013 and is the Chairman of the IASLC Education Committee. As the current chair of the education committee, he has been active in developing the IASLC medical oncology education syllabus. He is also appointed Adjunct Associate Professor at Duke-NUS Medical School. Currently, he serves as Associate Editor on Journal of Thoracic Oncology, and is a member of the IASLC molecular database taskforce.
Dr. Ann Toh is passionate about palliative and supportive care. Babies, children, adolescents and young adults hold special place in her heart. She spent the initial years of her working life after graduation training in KKWCH paediatric medicine subsequently passing her MRCPCH locally in 2015. She was subsequently mentored by Dr. Chong Poh Heng, Director and founder of STARPALs, the local paediatric home hospice for children.
Dr. Toh was involved training and education for paediatric palliative care for STARPALS nurses training during her time there and also involved in training and education for doctors, nurses and allied healthcare staff of Assisi hospice in preparation to the setting of up its paediatric ward. Dr. Toh has work in both home hospice and inpatient hospice paediatric palliative care settings and was involved in the setting up of the Assisi hospice paediatric ward when opened in 2017.
Her experience in palliative care include managing patients in various palliative care settings including Assisi hospice, NCCS Department of Palliative and Supportive care, Bright vision Hospital palliative ward and HCA hospice care (adult services). Dr. Toh is a current member of the LCPC Care of the Vulnerable Babies advisory committee and actively participated in the development of the Guidance for Comfort and Supportive Care of Vulnerable Babies published in 2018. Her research interests include grief and bereavement in adolescent and young adult and paediatric palliative care and humanism in healthcare professionals education.
Extent-of-care discussions are a crucial, it allows wishes to be honoured and preferences to be executed. However, these often-painful conversations are challenging for patients, families and the healthcare professionals who care for them, this is particularly so when the patient is a child, adolescent or young adult. Health care professionals working with paediatric oncology patients often find themselves navigators for the patients and families who and need to grapple with the tangled complex web of emotions, life experiences and stark reality of illness and loss. Based on simple lessons gleaned from her journey with her patients and their families, and various PEARLS she has inherited from colleagues of her multidisciplinary team, Dr. Toh shares principles that have guided her in her conversations with young patients and their families facing terminal illness and death.
Dr. Yu subspecialised in reproductive endocrinology and spent 9 months in Australia in training. She headed clinical work in IVF, menopause and gynaecological endocrinology since 1993. She was also Head of Department of Obstetrics & Gynaecology 1997 to 2003. She has many research interests in her subspecialty and was the pioneer of intrafallopian tube catheterisation, growth hormone augmentation in IVF, egg donation programme and ovarian tissue transplantation in SGH.
Dr. Yu participated in many research projects with and without pharmaceutical sponsorships. She was in the Institutional Review Board for 10 years culminating as the deputy chairman from 2005 to 2009.
Ovarian and sperm function can be damaged by surgery, radiation or chemotherapy thus affecting the future fertility of these men and women.The sperms and ovaries of young adults can be affected by tumours, radiation or chemotherapy as a result of malignancies. Bone marrow transplants involving whole body irradiation can be a treatment for malignant and non malignant conditions and usually cause permanent damage to the gametes.
Fertility preservation in young men involve mainly sperm freezing from masturbation.
Fertility preservation in young women comprise of oocyte freezing , embryo freezing or ovarian tissue freezing. All these techniques require IVF procedures and support. Fertility preservation also can be supported by hormonal treatment although this is not well evidenced.Awareness of the urgent need for referral for fertility preservation amongst healthcare workers is imperative. Counselling and team approach is important for decision for fertility preservation and may even involve parents of the affected person.
This discipline of fertility preservation has become more important in this decade as more young adults survive their medical conditions and expect to lead normal lives in the future.
Dr. Toh Chee Keong graduated from the National University of Singapore (NUS) in 1995. He received several scholarships and academic medals, including the Gibb’s gold medal and Dean’s list in its first year of inception. Dr. Toh completed his Masters of Medicine in Internal Medicine in 2000. He also obtained his membership at the Royal College of Physicians in the same year.
Dr. Toh received his advanced specialty training at the National Cancer Centre Singapore (NCCS). Under the Health Manpower Development Program, he was involved in drug screening research at Burnham Institute for Medical Research. In addition, he had a clinical attachment at the University of California, San Diego Cancer Centre.
Passionate in his field, Dr. Toh believes in sharing his knowledge with future generations of doctors. He has received grants from SingHealth Foundation and National Medical Research Council. Through his research and clinical works, he has published many papers in journals and written several book chapters. He is also involved in many clinical trials conducted in NCCS.
Dr. Toh has special interests in thoracic oncology and genitourinary oncology.
Dr. Prasad Iyer is a Consultant from the Children’s Cancer Centre, at KK Women's and Children's Hospital, Singapore. After completing his post-graduate training in Paediatrics in India, he went to the United Kingdom and completed his advanced specialist training in Manchester. He complemented this training with a further four years in paediatric and adolescent oncology at The Great North Children’s Hospital (Royal Victoria Infirmary) Newcastle (UK) and was conferred the Fellowship of the Royal College of Paediatrics and Child Health.
His area of clinical interests includes teenage and adolescent cancers. Besides treating paediatric and adolescent solid tumours he also manages leukaemias, lymphomas and has a keen interest in cellular therapy. He is actively involved as a teaching faculty in all three medical schools in Singapore and has an active interest in clinical research.
Management of Complex Oncology Draining Wound
To outline innovative options for managing draining oncology wounds and fistulae, and:• Constructing access windows or ports • Isolating drains or fistula• Securing drains and tubes• Containment of complex draining wounds
End of Life Skin Failure Versus Pressure Injury
To describe the clinical presentations of pressure injuries and end of life skin failure in end of life care.
Overcoming Challenges Associated with Malignant Wounds
Malignant wounds are evidence of the progression of disease and present significant challenges the presentation will include management of comfort, aesthetics, exudate, malodour, infection, bleeding.
Ms Lee Kim Hua
Senior Nurse Clinician (APN), National Cancer Centre Singapore
Ms Lee Kim Hua is a Senior Nurse Clinician (APN) at the National Cancer Centre Singapore. She obtained her Master of Science in Nursing (Acute Care Nurse Practitioner Programme with Oncology Minor) from the University of Pennsylvania, USA, in 2012 and a Bachelor of Health Science in Nursing from the University of Sydney, Australia in 2003.
She has practiced in the area of oncology for 15 years in the outpatient infusion unit. She is actively involved in reviewing and managing patients undergoing chemotherapy as well as patients with central venous catheters and external drainage catheters.
Senior Nurse Clinician and Advanced Practice Nurse (APN), National Cancer Centre Singapore
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