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Specialised Units

Animal Holding Unit

The Animal Facility supports oncology research, mainly in vivo tumor studies. Aims include pursuit of innovations in cancer therapy and diagnostic tests, developing novel cancer diagnostics, molecular and cell biology of cancer, genomic-based personalised treatment in oncology and gene therapy.

NCCS Animal Facility is licensed by Animal & Veterinary Service (AVS) and is fully accredited by Association for Assessment and Accreditation of Laboratory Animal Care International (AAALAC). The SingHealth IACUC oversees the animal care and use program while NCCS Research Biosafety Committee (RBC) provides institutional oversight to our biological agents work. A comprehensive occupational health & safety program is rolled out to our researchers and husbandry staff.

Our facility is a specific pathogen free (SPF) barrier facility with a differential pressurization system. It houses mice in individually ventilated cages and controlled environment. The facility serves only the animal research investigators from NCCS.

Biohazard Rooms

We have a negative pressure facility for virus propagation. It is equipped with biological safety cabinets which serve as an added precaution against biological agents. These rooms are equipped with individual air-conditioning system, ultraviolet and HEPA filters (which take care of the exhaust air). Ventilation is controlled to provide negative pressure with respect to the adjacent ante room.

Good Manufacturing Practice Rooms

The GMP facility comprises four production suites, configured with one Class B and three Class C suites. This facility is actively utilized to produce cellular therapy products for early phase (up to phase II) cancer immunotherapy clinical trials. It is also used for the final preparation of immune therapeutic agents (such as cancer vaccines, for all phases of clinical studies).

Collaborative Laboratory

The collaborative laboratory is available for aspiring scientists who are just starting their research work. Core equipment such as Incubators, Microplate Readers and the whole range of equipments required for histological work (refer to Histology Capabilities) are provided along with bench space. The availability of bench space allows scientists to work on small projects before obtaining enough results for successful applications for bigger grants.