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Our Research



Title of Study Contact Investigator Status
Multimodal Integration of Data for Breast Cancer Risk Prediction (2024)
Dr Wong Fuh Yong
Dr Ryan Ying-Cong Tan ​
Ongoing

 Abstract
Clinicopathological characteristic of HER2 low breast cancers in the Singapore population (2023)
​Dr Mihir Gudi
​Ongoing

Abstract
​Inflammatory breast cancer in Singapore and validation of a diagnostic score (2023)
​Dr Sim Yirong
​Ongoing

Abstract
Economic evaluation of a risk-based breast cancer screening approach in Singapore (2023)
Dr Wong Fuh Yong
Dr Li Jingmei ​
Ongoing

Abstract
Patient characteristics and breast cancer outcomes (2023)
​Dr Ryan Ying-Cong Tan
​Ongoing

Abstract
Assessing the effect and outcome of axillary radiotherapy in patients with cN0 disease who are then yN0 but have evidence of treatment effect in the nodes post neoadjuvant chemotherapy on sentinel lymph node biopsy (2023)
​Dr Faye Lim
​Ongoing

Abstract
Axillary management of breast cancer patients with isolated chest wall recurrence after mastectomy (2022)
​Dr Lim Geok Hoon
​Ongoing

Abstract
Review of ductal carcinoma in-situ and invasive carcinoma in breast fibroepithelial lesions (2022)
​Dr Tan Si Ying
​Ongoing

Abstract
BCS vs mastectomy: Long-term efficacy for primary operable in-situ and early stage breast cancers (2022)
​Dr Sarbina Ng
​Ongoing

Abstract
A study to evaluate clinical-radiological-pathological concordance in patients with invasive lobular carcinoma of the breast (2022)
​Dr Sarbina Ng
​Ongoing

Abstract
A quantitative and qualitative study of factors influencing delayed presentation, diagnosis and treatment of breast cancer patients who present with locally-advanced or metastatic disease (2022)
​Dr Sarbina Ng
Ongoing

Abstract
Encysted papillary carcinoma of the breast: an institutional case series and literature review (2021)
​Dr Sim Yirong
​Ongoing

Abstract
Use of cyclin-dependent kinase (CDK) 4/6 inhibitors in treatment of metastatic breast cancer patients in Singapore (2021)
Dr Lim Hsuen Elaine 
 Ongoing




Retrospective study on outcomes in metaplastic breast cancer (2021)
​Dr Nelson Yit Ling Fung 

Prof Tan Puay Hoon



 Ongoing




Improving Breast Cancer Risk Prediction in Singapore Women with a Hybrid Machine-Learning Model (2021)
Dr Ryan Ying-Cong Tan

Dr Veronique Tan

Dr Wong Fuh Yong
Ongoing

AI-driven Survival Modelling in Breast Cancer (2021)​Dr Wong Fuh Yong

​On-going

Abstract

Survival outcomes of Advanced Breast Cancer Patients in Singapore (2020)

Dr Rachel Sim Hui Zhen

Dr Yap Yoon Sim ​

​On-going

Abstract

PREoperative therapy and Supportive Care in EarLy & Locally Advanced breast cancers – PreSCella Dr Tira Tan Jing Ying  On-going 
Outcomes of Mucinous Breast Cancer

Dr Ryan Ying-Cong Tan

On-going 
Investigating the role and impact of discordant hormone receptor status in newly diagnosed breast cancer patients  Dr Grace Kusumawidjaja

On-going 

Abstract

Retrospective review of imaging findings and surveillance outcomes after oncoplastic breast conserving surgery Dr Lester Leong Chee Hao 

On-going 

Abstract

Correlation of Neutrophil-Lymphocyte and Albumin-Globulin Ratios With Outcomes in Patients With Breast Cancer Undergoing Neoadjuvant Chemotherapy or Upfront Surgery. J Breast Cancer. 2024 Apr;27(2):e9. https://doi.org/10.4048/jbc.2023.0242. Yang SH, Tey Min Li, Zhou Siqin, Phyu Nitar, Hanis M, Sim Yirong, Grace K, Chay WY, Wong FY, Wong RX.

Dr Shi Hui Yang​ Full text​
​Determining the Need for Metastatic Staging in Patients with Bilateral Breast Cancers. Curr. Oncol.2024, 31, 1936–1946. https://doi.org/10.3390/curroncol31040145. Alcantara VS, Chan SMZ, Wong FY, Allen JC, Lim GH.
​Dr Lim Geok Hoon
Full text
How Asian Breast Cancer Patients Experience Unequal Incidence of Chemotherapy Side Effects: A Look at Ethnic Disparities in Febrile Neutropenia Rates. Cancers 2023, 15, 3590. https://doi.org/10.3390/cancers15143590. Lim ZL, Ho PJ, Hartman M, Tan ET, Riza NKBM; Lim EH; Nitar P; Joint Breast Cancer Registry (JBCR); Wong FY; Li J.
Dr Li Jingmei
Dr Lim Hsuen Elaine​
Full text
Modern-era radiotherapy and ischaemic heart disease-related mortality outcomes in Asian breast-cancer patients. Contemp Oncol (Pozn) 2022; 26 (1): 59–68. Ling Fung Nelson Yit, Choon Ta Ng, Fuh Yong Wong, Zubin Master, Siqin Zhou, Wee Loon Ng.
​Dr Ng Wee Loon
Full text
Male breast cancer: a Singapore perspective. ANZ J Surg 2022; 92(6):1440-1446. Joshua S. H. Lim, Yirong Sim, Joanne Ngeow,Jeanette Yuen, Veronique K. M. Tan, Benita Kiat Tee Tan, Wei-Sean Yong, Chow Yin Wong,Sue Zann Lim, Julie Liana B. Hamzah,Si Ying Tan,Fuh Yong Wong, Preetha Madhukumar.
​Dr Joshua Lim Sheng HaoFull text
The Impact of Statin Use and Breast Cancer Recurrence - A Retrospective Study in Singapore. Front. Oncol. 2022 Front. Oncol. 2022; 12: 835320. Sim Y, Lim C, Phyu N, Tan KTB, Chew LST, Wong CY, Madhukumar P, Yong WS, Lim SZ, Hamzah JLB, Tan SY, Chay WY, Wong FY, Tan PH,Tan VKM.
Dr Sim Yirong​
Full text​
HER2 expression, copy number variation and survival outcomes in HER2-low non-metastatic breast cancer: an international multicentre cohort study and TCGA-METABRIC analysis. BMC Med 2022; 20: 105. Tan R, Ong WS, Lee KH, Lim AH, Park S, et al. 
Dr Ryan Ying-Cong Tan
Full text
Multi-center evaluation of artificial intelligent imaging and clinical models for predicting neoadjuvant chemotherapy response in breast cancer. Breast Cancer Res Treat 2022; 10.1007/s10549-022-06521-7. Tan HQ, Hian OH, Kumaran AM, Tan TJ, Cong TRY, et al.
Dr Nei Wen Long​
​Full text

Effects of housing value and medical subsidy on treatment and outcomes of breast cancer patients in Singapore: A retrospective cohort study. The Lancet Regional Health - Western Pacific 6 (2021) 10 0 065. F.Y. Wong, R.X. Wong, S. Zhou et al.


 


 Dr Wong Fuh Yong Full text

Contrasting Epidemiology and Clinicopathology of Female Breast Cancer in Asians vs the US Population. J Natl Cancer Inst. 2019 Dec 1;111(12):1298-1306. Lin CH, Yap YS, Lee KH, Im SA, Naito Y, Yeo W, Ueno T, Kwong A, Li H, Huang SM, Leung R, Han W, Tan B, Hu FC, Huang CS, Cheng AL, Lu YS; Asian Breast Cancer Cooperative Group.                


 

Dr Yap Yoon Sim 

Full text

The impact of radiotherapy and histological risk factors on outcomes in malignant phyllodes tumors. Clin Breast Cancer.  2020 Dec;20(6):e695-e700. Wong RX, Koh YS, Wong FY, Kusumawidjaja G, Ng WL, Yeo RMC, Farid M, Sheng, Chan JY, Yan Z, Gudi MA, Tan PH



 

Dr Wong Ru Xin Abstract

  Full text  

Human epidermal growth factor receptor 2 positive rates in invasive lobular breast carcinoma: The Singapore experience. World J Clin Oncol 2020; 11(5): 283-293. Ga-Jing Kee, Ryan Ying-Cong Tan, Sultana Rehena, Joycelyn Jie-Xin Lee, Ma Wai-Wai Zaw, Wei-Xiang Lian, Joe Yeong, Su-Ming Tan, Swee-Ho Lim, Benita Kiat-Tee Tan, Yoon-Sim Yap, Rebecca Alexandra Dent, Fuh-Yong Wong, Guek-Eng Lee


  Dr Ryan Ying-Cong Tan Full text
Patterns of relapse after neoadjuvant chemotherapy in breast cancer: implications for surveillance in clinical practice. Breast Cancer Res Treat. 2019 Aug;177(1):197-206.  Saw S, Lim J, Lim SH, Wong M, Lim C, Yap YS
Dr Yap Yoon Sim

Abstract

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Validation of Modified Breast Graded Prognostic Assessment for breast cancer patients with brain metastases: extra-cranial disease progression is an independent risk factor. Ann Palliat Med 2019;8(4):390-400. Qingyuan Zhuang, Ru Xin Wong, Wei Xiang Lian, You Quan Li, Fuh Yong Wong


 Dr Zhuang Qingyuan Full text

Gestational breast cancer in Singapore women. Proceedings of the 2018 San Antonio Breast Cancer Symposium; 2018 Dec 4-8; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2019;79(4 Suppl):Abstract nr P4-10-12. QT Tan, FY Wong, VS Alcantara, R Ganguly and KW-J LohIn


  Dr Tan Qing Ting  Abstract

Breast cancer anatomic staging with biological risk Score is effective and simple to use. Melbourne International Breast Conference Oct 2018. WX Lian, RX Wong, YH Seow, YS Yap, JHC Lim, FY Wong
 

  Dr Wong Ru Xin

 Full text
Validation of the AJCC 8th prognostic system for breast cancer in an Asian healthcare setting. Breast. 2018 Apr 17;40:38-44. Wong RX, Wong FY, Lim J, Lian WX, Yap YS
  Dr Wong Ru Xin

Abstract

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Surgery for early breast cancer in the extremely elderly leads to improved outcomes - An Asian population study. Breast. 2017 Dec; 36:44-48. Lee CM, Zheng H, Tan VK, Tan TJ, Kanesvaran R, Wong FY, Sim YR, Yong WS, Madhukumar P, Ong KW, Tan BK

A/Prof Benita Tan Kiat Tee

Abstract

Full text

Screening uptake differences are not implicated in poorer breast cancer outcomes among Singaporean malay women. J Breast Cancer. 2017 Jun;20(2):183-191. Wong Ru Xin, Li-lian Kwok, Wong Fuh Yong

Dr Wong Ru Xin Full text

Outcome after neoadjuvant chemotherapy in Asian breast cancer patients. Cancer Med. 2017 Jan; 6(1): 173–185. Li Yan Lim, Hui Miao, Joline S.J.Lim, Soo Chin Lee, Nirmala Bhoo-Pathy, Cheng Har Yip, Nur Aishah B.M.Taib, Patrick Chan, Ern Yu Tan, Swe Ho Lim, Geok Hoon Lim, Evan Woo, Yia Swam Tan, Jung Ah Lee, Mabel Wong, Puay Hoon Tan, Kong Wee Ong, Fuh Yong Wong, Yoon Sim Yap, Mikael Hartman


 

 Dr Yap Yoon Sim Full text

Clinicopathological characteristics and treatment outcomes in patients with stage I-III invasive Lobular carcinoma of the breast (ILC) treated at the National Cancer Centre Singapore. 2016 ASCO Annual Meeting. J Clin Oncol 2016 suppl; abstr. Joycelyn Jie Xin Lee, Fuh-Yong Wong, Benita Tan, Swee Ho Lim, Sze Huey Tan, Joanne YY Ngeow, Rebecca Alexandra Dent


 

 Dr Joycelyn Jie Xin Lee  Abstract

Prognostic role of adjuvant radiotherapy in triple-negative breast cancer: A historical cohort study.Int J Cancer. 2015 Nov 15;137(10):2504-12. Bhoo-Pathy N, Verkooijen HM, Wong FY, Pignol JP, Kwong A, Tan EY, Aishah Taib N, Nei WL, Ho GF, Tan B, Chan P, Lee SC, Hartman M, Yip CH, Dent R


Dr Rebecca Alexandra Dent   Full text