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Adj Assoc Prof Tan Ngian Chye

MBBS, M Med (Surgery), FRCSEd (Gen)

Senior Consultant

National Cancer Centre Singapore

Specialty: Surgical Oncology, Surgical Oncology

Sub-specialties: Head & Neck, Thyroid, Skin & Melanoma

Conditions Treated by this Doctor:
Head and Neck Cancer, Melanoma, Skin Cancer, Thyroid Cancer, Thyroid Diseases.

Clinical Appointments

  • Senior Consultant SingHealth Duke-NUS Head and Neck Centre
  • Senior Consultant Department of General Surgery Singapore General HospitalSingapore General Hospital
  • Senior Consultant Division of Surgical Oncology National Cancer Centre SingaporeNational Cancer Centre Singapore

Academic Appointments

  • Director
  • Adjunct Associate Professor SingHealth Duke-NUS Oncology Academic Clinical Programme
  • Director, Device Development SingHealth Duke-NUS Surgery Academic Clinical Programme
  • Physician Faculty Member


Dr Tan Ngian Chye completed his general surgical training in 2006 and went on to pursue sub-specialty training in both head and neck ablative surgery and reconstructive microsurgery. After completing his fellowship in head and neck surgical oncology with Professor Soo Khee Chee, he went on to do another fellowship in reconstructive microsurgery at Chang Gung Memorial Hospital, Taiwan. 

Currently, he is a Senior Consultant and Director, Education of the SingHealth Duke-NUS Head and Neck Centre. At the same time, he is the clinical lead for head & neck oncologic reconstruction and skin malignancies. Dr Tan is also a member of the NCCS Cancer Service Line development for nasopharyngeal carcinoma, thyroid cancer and head & neck cancers.



  • Fell, Roy Coll of Surg, Edinburgh, UNITED KINGDOM, Royal College of Surgeons, Edinburgh, 2007
  • Master of Medicine (Surgery), SINGAPORE, National University of Singapore, 2003
  • B of Med, B of Surg, SINGAPORE, National University of Singapore, 1999


Professional Appointments and Committee Memberships



  • Fellow, FRCSEd (Gen), Royal College of Surgeons of Edinburgh, United Kingdom 
  • Registered Specialist Medical Practitioner, Singapore Medical Council 
  • Fellow, FAMS, Academy of Medicine, Singapore 
  • Member, General Medical Council, United Kingdom 
  • Registered Medical Practitioner, Singapore Medical Council



  • RiSE Award 2017, Outstanding Faculty Award, Singapore Health Services, 2017
  • SKC Publish! Award 2015, Singapore Health Services, 2015
  • SingHealth Publish! Award 2014, Singapore Health Services, 2014 
  • SingHealth Publish! Award 2013, Singapore Health Services, 2013

Publications and Research Trials

  • Ong CJ, Shannon NB, Mueller S, Lek SM, QiuX, Chong FT, Li K, Koh KKN, Tay GCA, Skanthakumar T. Hwang JSG, Lim TKH, Ang MK, Tan DSW, Tan NC, Tan HK, Soo KC, Iyer NG. A three gene immunohistochemical panel serves as an adjunct to clinical staging of patients with head and neck cancer. Oncotarget. 2017 Jun 19. Doi: 10.18632/Oncotarget.18568. [Epud ahead of print] PMID : 28645105 
  • Thong P, Lee K, Toh HJ, DongJ, Tee CS, Low KP, Chang PH, Bhuvaneswari R, Tan NC, Soo KC. Early assessment of tumour response to photodynamic therapy using combined diffuse optical and diffuse correlation spectroscopy to predict treatment outcome. Oncotarget. 2017 Mar 21;8(12):19902-19913.doi: 10.18632/Oncotarget.15720. PMID: 28423634 
  • See A, Iyer NG, Tan NC, Teo C, Ng J, Soo KC, Tan HK Distant Metastasis as the sole initial manifestation of well-differentiated thyroid carcinoma Eur Arch Otorhinolaryngol. 2017 Jul; 274(7):2877-2882. PMID: 28382395 
  • Jang JH, Tan HK, Iyer NG, Soo KC, Tan NC Nasopharyngectomy with operating microscope: A case series Am J Otolaryngol. 2017 Jan-Feb; 38(1):82-86 doi: 10.1016/j.amjoto.2016.07.008 PMID 2783294 
  • Tian B, Iyer NG, Tan HK, Tay AC, Soo KC, Tan NC Novel technique of creating a seal for the vacuum-assisted closure system application in complex head and neck wounds. Head Neck 2016 Dec:38(12):E2523-E2526. Doi: 10.1002/hed.24563. PMID: 27534613 
  • Wee HE, Azhar R, Tang PY, Teo TH, Iyer NG, Tan HK, Tan NC Diagnostic Pitfall: Adenois cystic carcinoma of the tongue presenting as an isolated hypoglossal nerve palsy, case report and literature review. Int J Surg Case Rep. 2016;25:102-5. 
  • Ong W, Zhao R, Lui B, Tan W, Ebrahimi A, Clark JR, Soo KC, Tan NC, Tan HK, Iyer NG Prognostic Significance of Lymph Node Density in Squamous Cell Carcinoma of the Tongue. Head Neck 2016; April;38 Suppl 1:E859-66 (Article; e-Published Ahead of print) 
  • Lim SJ, Iyer NG, Ooi LL, Koong HN, Chung AY, Tan HK, Soo KC, Tan NC Metastasectomy for Metachronous Pulmonary and Hepatic Metastases from Nasopharyngeal Carcinoma: Report of 6 cases and review of the literature. Head Neck 2016; Feb;38(2):E37-40 (e-Published Ahead of Print) JIF: 2.641 
  • Koh PT, Tan NC Large Intrathoracic Goiter: When Sternotomy is Unavoidable. Asian Cardiovasc Thorac Ann 2016; Feb; 24(2):207-10 PMID: 26472934 
  • Tan NC, Lin PY, Kuo PJ, Tsai YT, Chen YC, Nguyen KT, Kuo YR An Objective Comparison Regarding Rate of Fistula and Stricture Among Anterolateral Thigh, Radial Forearm, and Jejunal Free Tissue Transfers in Circumferential Pharyngo-esophageal Reconstruction Microsurgery 2015; 35(5):345-349 (Article; e-Published Only (Never in Print) JIF: 2,421

Research Trials

  • Towards an intuitive robot-assisted device for dexterous microsurgical task. Principal Investigator, SUTD-Surgery ACP Strategic Joint Research Fund (Apr 2016 – Apr 2017) 
  • High intensity focused ultrasound ablation of benign thyroid nodules using erosion mechanism, Principal Investigator, NTU-Surgery Academic Clinical Program (ACP) Strategic Joint Research Fund (Mar 2016 – Feb 2017) 
  • Oral and pharyngo-cutaneous fistula occlusion device: Development and prototype. Principal Investigator, Surgery Academic Clinical Program (ACP) Seed Grant, (Jan 2016 – Mar 2017) 
  • Lyt:iT-open deep cavity surgical lighting. Principal Investigator, National Health Innovation Centre (HNIC) Innovation to develop I2D Grant (Jan 2016- Dec 2017) 
  • Photodyamic diagnosis and therapy of early oral carcinoma using Chlorin e6-EGFR antibody conjugated gold nanoparticles. Co PI, NCCRF Seed Grant (Jul 2014 – Jan 2018) 
  • Targeted therapy by combining photodynamic therapy with antiangiogenic nimotuzmab for improving outcome of cancer treatment. Co-PI, NMRC CSIRG (11 Dec 2012 – Dec 2017)