Asst Prof Sim Yirong

About

Dr. Sim Yirong graduated with a medical degree and PhD from the University of Cambridge in 2009, and obtained her fellowship with Royal College of Surgeons Edinburgh in 2016. She did her Advanced Breast Surgery Fellowship (Oncoplastic Surgery and Translational Research) at Seoul National University Hospital from 2019-2020, under the Healthcare Manpower Development Programme (HMDP). Her focus and interests are in breast cancer research and in education. 

She is currently a Senior Consultant at the Department of Breast Surgery in Singapore General Hospital and National Cancer Centre Singapore, and is the Director of Research for the SingHealth Duke-NUS Breast Centre.

Education and Training

• MB BChir (Cantab)
• MA (Cantab)
• PhD (Cantab)
• MMed (Gen Surg)
• FRCS (Edin)
  

Professional Appointments and Committee Memberships

• Director of Research, SingHealth Duke-NUS Breast Centre
• Core Faculty and Physician Faculty Member, SingHealth General Surgery Residency Pro-gramme

Awards

• SingHealth Service with a Heart Award, 2023
• SingHealth Quality Service Awards
  
• 2022 (Star award), 
• 2020, 
• 2019 (Silver)
  
• SingHealth Long Service Award, Long Service Award, 2021
• NCCS Research Publication Award Q1 2022
• Healthcare Manpower Development Programme (HMDP) Fellowship Award in Advanced Breast Surgery Fellowship – Oncoplastic Surgery and Translational Research, 2018
• Residency in Singhealth Excels (RiSE) Award Winners, Inspiring Resident Educator Award, 2014
  

Research Interests

Grants

• Population-based, Unified, Learning System for Enhanced and Sustainable Health (PULSES) Grant, 2023
• NCCS Cancer Research Fund, 2021
• Surgery ACP Quality Improvement Project Award, 2018
• Surgery ACP Surgeon-Scientist Strategic Start-up (S4G) Grant, 2016
  

Publications

1. Y Sim, C Lim, N Phyu, KTB Tan, LST Chew, CY Wong, P Madhukumar, WS Yong, SZ Lim, JL Bte Hamzah, SY Tan, WY Chay, FY Wong, PH Tan, VKM Tan. study in Singapore. Frontiers in Oncolo-gy. 2022. 12:835320.  Doi:10.3389/fonc.2022.835320 The Impact of Statin Use and Breast Cancer Recurrence – a Retrospective 
   
2. Sim Y, Ng GXP, Ng CCY, Rajasegaran V, Wong SF, Liu W, Guan P, Nagarajan S, Ng WY, Thike AA, Lim JCT, Nasir NDB, Tan VK, Madhukumar P, Yong WS, Wong CY, Tan BKT, Ong KW, The BT, Tan PH. A Novel Genomic Panel as an Adjunctive Diagnostic Tool for the Characterization and Profil-ing of Breast Fibroepithelial Lesions – BMC Medical Genomics (Open) 2019. 12(1):142. Doi:10.1186/s12920-019-0588-2
   
3. Sim Y,  VKM Tan, N Azleen, GH Ho, CY Wong, P Madhukumar, BKT Tan, WS Yong, KW Ong. Bilat-eral Breast Cancers in an Asian Population, and a Comparison between Synchronous and Meta-chronous Tumours.  ANZ Journal of Surgery 2018; 88(10):982-987
   
4. Sim Y, Tan VKM, Ho GH, Wong CY, Madhukumar P, Tan BKT, Yong WS, Ng YYR, Ong KW. Contra-lateral prophylactic mastectomy in an Asian population: A single institution review. The Breast. 2014; 23 (1): 56-62
5. Choo ALE, Sim LSJ, Sittampalam K, Tan WC, Tay AZE, Nadarajah R, Tan VKM, Sim Y. Breast Me-tastasis from Endometrial Clear Cell Carcinoma: A Case Report and Review of the Literature. Frontiers in Oncology (2022) 12:1070744. Doi:10.3389/fonc.2022.1070744
   
6. Tan HJ, Tan PH, Leong LCH, Tan VKM, Tan BKT, Lim SZ, Madhukumar P, Wong CY, Yong WS, Sim Y.  Encapsulated Papillary Carcinoma of the Breast: An Institutional case series and literature re-view.  Cancer Medicine. 2023. 12(10):11408-11416. Doi:10.1002/cam4.5855
   
7. Bong TS, Tan JK, Ho JT, Tan PH, Lau WS, Tan TM, Wong JS, Tan VK, Tan BK, Madhukumar P, Yong WS, Lim SZ, Wong CY, Ong KW, Sim Y. Atypical Ductal Hyperplasia of the Breast on Core Needle Biopsy: Risk of Malignant Upgrade on Surgical Excision. J Breast Cancer. 2022. Feb;25(1):37-48. doi: 10.4048/jbc.2022.25.e7. PMID: 35199500; PMCID: PMC8876544.
   
8. JJ Chan, Y Sim, SGW Ow, JSJ Lim, G Kusumawidjaja, Q Zhuang, TX Wong, FY Wong, VKM Tan, TJY Tan. The Impact of COVID-19 on recommendations for Breast cancer care: The Singapore Expe-rience. Endocr Relat Cancer. 2022. Sep 27(9): R307-R327. Doi:10.1530/ERC-20-0157. PMDI:32544879.
   
9. Tay THC, Ng WY, Ong KW, Wong CY, Tan BKT, Yong WS, Madhukumar P, Tan WKM, Lim SZ, Sim Y. Impact of hormonal status on ductal carcinoma in situ of the breast: Outcome and prognostic factors. Breast J. 2020; 26: 937– 945. https://doi.org/10.1111/tbj.13738
   
10. Lim SZ, Kusumawidjaja G, Mohd Ishak HM, Tan BKT, Tan SY, Hamzah JL, Madhukumar P, Yong WS, Wong CY, Sim Y, Lim GH, Lim SH, Tan SM, Wong FY, Tan VKM. Outcomes of Stage I and II Breast Cancer with Nodal Micrometastases Treated with Mastectomy without Axillary Therapy. Breast Cancer Res Treat. 2021 Oct;189(3):837-843. doi: 10.1007/s10549-021-06341-1. Epub 2021 Aug 3.
    
11. Wong FY, Wong RX, Zhou S, Ong WS, Pek PP, Yap YS, Tan BKT, Ngeow JYY, Tan VKM, Sim Y, Tan SM, Lim SH, Madhukumar P, Tan TJY, Loh KWJ, Ong MEH, Wong TH, Joint Breast Cancer Registry. Effects of housing value and medical subsidy on treatment and outcomes of breast cancer pa-tients in Singapore: A retrospective cohort study. Lancet. 2020 Dec 8; 6(100065). doi: https://doi.org/10.1016/j.lanwpc.2020.100065.