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Clin Asst Prof Koh Puay Theng Tina

Clin Asst Prof Koh Puay Theng Tina


Senior Consultant

National Heart Centre Singapore

Specialty: Surgical Oncology, Thoracic Surgery

Clinical Interest: Thoracic Oncology

Clinical Appointments

  • Thoracic Surgeon SingHealth Duke-NUS Lung Centre
  • Senior Consultant SingHealth Duke-NUS Transplant Centre
  • Senior Consultant Department of Cardiothoracic Surgery National Heart Centre SingaporeNational Heart Centre Singapore
  • Senior Consultant Division of Surgery & Surgical Oncology National Cancer Centre SingaporeNational Cancer Centre Singapore
  • Senior Consultant Thoracic Surgery Sengkang General HospitalSengkang General Hospital


Clin Asst Prof Tina Koh obtained her medical degree from National University of Singapore in 2004.  After housemanship, during her medical officer rotation, she developed a keen interest in Cardiothoracic Surgery.  Hence she began her advanced surgical training in Cardiothoracic Surgery in the National Heart Centre Singapore (NHCS). After completion of her training and received a gold medal for her specialist exit examinations, she decided to pursue further in Thoracic Surgery.  She went to South Korea to train under the regional expert surgeon of Video-assisted Thoracoscopic (VATS) Surgery in Seoul National University Bundang Hospital.  Upon her return she work at the National Cancer Centre (NCC) as an Associate Consultant doing Thoracic surgery and became a Senior Consultant. With the increasing incidence and earlier detection of lung malignancy and hence surgical volume, she is setting up the Surgical Lung Cancer database.

She is also enthusiastic about undergraduate and post-graduate training.  She is a clinical educator in Yong Loo Lin Medical School.  In addition, she later joined NHCS as a Senior Consultant and is a member of the Chapter of Cardiothoracic Surgery.

Clin Asst Prof Koh's interests include lung cancer, mediastinal tumours, airway and pleural disease as well as benign conditions such as pneumothorax, with a main focus on minimally invasive thoracic surgeries.



Professional Appointments and Committee Memberships

  • ​Senior Consultant, Department of Cardiothoracic Surgery, National Heart Centre Singapore
  • Clinical Assistant Professor at Duke-NUS Medical School
  • Clinical Educator of Yong Loo Lin Medical School


Research Interests


  • Elucidating the genomic architecture of Asian EGFR-mutant lung adenocarcinoma through multi-region exome sequencing. Nahar R, Zhai W, Zhang T, Takano A, Khng AJ, Lee YY, Liu X, Lim CH, Koh TP, Aung ZW, Lim TKH, Veeravalli L, Yuan J, Teo ASM, Chan CX, Poh HM, Chua IML, Liew AA, Lau DPX, Kwang XL, Toh CK, Lim WT, Lim B, Tam WL, Tan EH, Hillmer AM, Tan DSW. Nat Commun. 2018 Jan 15;9(1):216.
  • Clonal MET Amplification as a Determinant of Tyrosine Kinase Inhibitor Resistance in Epidermal Growth Factor Receptor-Mutant Non-Small-Cell Lung Cancer. Lai GGY, Lim TH, Lim J, Liew PJR, Kwang XL, Nahar R, Aung ZW, Takano A, Lee YY, Lau DPX, Tan GS, Tan SH, Tan WL, Ang MK, Toh CK, Tan BS, Devanand A, Too CW, Gogna A, Ong BH, Koh TP, Kanesvaran R, Ng QS, Jain A, Rajasekaran T, Yuan J, Lim TKH, Lim AST, Hillmer AM, Lim WT, Iyer NG, Tam WL, Zhai W, Tan EH, Tan DSW. J Clin Oncol. 2019 Apr 10;37(11):876-884. 2019 Jan 24.
  • Two Cancers Arising from Different Mesenchymal Origins: An Unexpected Connection over Time and Space. N Putri, SM Lek, N Shannon, Koh T. 2019 Case Reports in Clinical Medicine 08(05):99-104
  • Bystander CD8+ T cells are abundant and phenotypically distinct in human tumour infiltrates. Simoni Y, Becht E, Fehlings M, Loh CY, Koo SL, Teng KWW, Yeong JPS, Nahar R, Zhang T, Kared H, Duan K, Ang N, Poidinger M, Lee YY, Larbi A, Khng AJ, Tan E, Fu C, Mathew R, Teo M, Lim WT, Toh CK, Ong BH, Koh TP, Hillmer AM, Takano A, Lim TKH, Tan EH, Zhai W, Tan DSW, Tan IB, Newell EW. Nature. 2018 May;557(7706):575-579. Epub 2018 May 16
  • Surgical Management of Metastatic Colorectal Cancer: A Single-Centre Experience on Oncological Outcomes of Pulmonary Resection vs Cytoreductive Surgery and HIPEC. Wong EYT, Tan GHC, Ng DWJ, Koh TP, Kumar M, Teo MCC. J Gastrointest Cancer. 2017 Dec;48(4):353-360
  • Large intrathoracic goiter: When sternotomy is unavoidable. Koh PT, Tan NC. Asian Cardiovasc Thorac Ann. 2016 Feb;24(2):207-10
  • Thoracoscopic visualization of a misdirected paravertebral catheter. Phoon P, Thong SY, Koh PT, Loh K. Can J Anaesth. 2015 Jul;62(7):830-1
  • Impact of Smoking and Brain Metastasis on Outcomes of Advanced EGFR Mutation Lung Adenocarcinoma Patients Treated with First Line Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors. Jain A, Lim C, Gan EM, Ng DZ, Ng QS, Ang MK, Takano A, Chan KS, Tan WM, Kanesvaran R, Toh CK, Loo CM, Hsu AA, Devanand A, Lim CH, Koong HN, Koh PT, Fong KW, Yap SP, Kim SW, Chowbay B, Oon L, Lim KH, Lim WT, Tan EH, Tan DS. PLoS One. 2015 May 8;10(5):e0123587

Research Trials

  • ​Surgical Lung Cancer Database