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Dr Ang Soo Fan

Dr Ang Soo Fan


Senior Consultant

National Cancer Centre Singapore

Specialty: Medical Oncology

Clinical Interest: Upper Gastrointestinal

Conditions Treated by this Doctor:
Oesophagus Cancer, Stomach Cancer.

Clinical Appointments

  • Senior Consultant Division of Medical Oncology National Cancer Centre SingaporeNational Cancer Centre Singapore

Academic Appointments

  • Clinical Lecturer


​Dr Ang Soo Fan holds dual appointments in National Cancer Centre Singapore and Penang Adventist Hospital since 2012. He is also a clinical lecturer at Yong Loo Lin School of Medicine Singapore. He was awarded with Bachelor of Medicine and Surgery (MBBS) in University of Malaya, Malaysia in 2001, membership of Royal College of Physicians of Edinburgh, United Kingdom in 2007 and obtained specialist accreditation for Medical Oncology, Academy of Medicine, Singapore in 2011.

He sub –specializes in gastrointestinal cancers and has a research interest in liver cancer and personalized treatments. He has been an invited speaker in both local and international seminars and conferences on his research. For example, he spoke about Choosing the Best First Line Combination Therapy for Metastatic Colorectal Cancer at the Colorectal Cancer Symposium earlier this year in Sri Lanka. He also talked about Management of borderline resectable liver only metastases in CRC during the Roche Oncology Scientific Meeting (ROSM) in March 2015. 


​M.B.B.S (2001)

Professional Appointments and Committee Memberships

​Professional Appointment

  • 2012 - Current  Consultant, Penang Adventist Hospital Consul
  • 2012 - Current  Department of Medical Oncology, National Cancer Centre

Committee Memberships

  • 2011  Fellow of Academy of Medicine Singapore (FAMS)
  • 2010   Fellow of American Society of Clinical Oncology (ASCO)
  • 2008  Member of Singapore Society of Oncology (SSO)
  • 2007  Member of Royal Colleges of Physicians of Edinburgh (UK)


  • ​2011/12 Singapore Health Quality Service Award
  • 2006 Klang General Hospital Excellence Service Award

Research Interests


  • The Singapore Liver Cancer Recurrence (SLICER) Score for relapse prediction in patients with surgically resected hepatocellular carcinoma. Ang SF, Ng ES, Li H, Ong YH, Choo SP, Ngeow J, Toh HC, Lim KH, Yap HY, Tan CK, Ooi LL, Cheow PC, Chung AY, Chow PK, Foo KF, Tan MH. PLoS One. 2015 Apr 1
  • Minimal clinically important difference (MCID) for the functional assessment of cancer therapy: Cognitive function (FACT-Cog) in breast cancer patients. Cheung YT, Foo YL, Shwe M, Tan YP, Fan G, Yong WS, Madhukumar P, Ooi WS, Chay WY, Dent RA, Ang SF, Lo SK, Yap YS, Ng R, Chan A. J Clin Epidemiol. 2014; Epub 2014 Mar 18.
  • Adoptive T-cell transfer and chemotherapy in the first-line treatment of metastatic and/or locally recurrent nasopharyngeal carcinoma. Chia WK, Teo M, Wang WW, Lee B, Ang SF, Tai WM, Chee CL, Ng J, Kan R, Lim WT, Tan SH, Ong WS, Cheung YB, Tan EH, Connolly JE, Gottschalk S, Toh HC. Mol Ther. 2014 Jan;22(1):132-9
  • Identification of serum monocyte chemoattractant protein-1 and prolactin as potential tumor markers in hepatocellular carcinoma. Soo-Fan Ang, Wang WW, Kumar R, Heah C, Utama A, Tania NP, Li H, Tan SH, Poo D, Choo SP, Chow WC, Tan CK, Toh HC. PLoS One. 2013 Jul 18
  • Effects of Chemotherapy and Psychosocial Distress on Perceived Cognitive Disturbances in Asian Breast Cancer Patients.  Yin Ting Cheung, Maung Shwe, Wai Keung Chui, Wen Yee Chay, Soo-Fan Ang, Rebecca Alexandra Dent, Yoon Sim Yap, Soo Kien Lo, Raymond Chee Hui Ng, and Alexandre Chan. The Annals of Pharmacotherapy. Ann Pharmacother. 2012 Dec; 46(12):1645-55.
  • Activity of Thalidomide and Capecitabine in Advanced Hepatocellular Carcinoma with poorer liver function. Soo-Fan Ang, Sze-Huey Tan, Han-Chong Toh, Donald YH Poon, Simon YK Ong, Kian-Fong Foo, Su-Pin Choo. Am J Clin Oncol. 2012 Jun; 35(3):222-7
  • Infectious Causes of Cancer. 2010. Salubris, NCCS’s public Newsletter, Singapore
  • Latest Treatment Options for Liver Cancer. 2009. Medical Grapevine, Singapore
  • EBV-specific T cells in combination with chemotherapy show promising activity in the front-line treatment of patients with advanced nasopharyngeal carcinoma. Submitted to Science Translational Medicine on 18.7.2013
  • Protein expression of cancer-testis antigens in hepatocellular carcinoma from Singapore and correlation with clinical characteristics and outcomes. Soo-Fan Ang, Geoffrey Y. Ku, Han-chong Toh, Sze-Huey Tan, Giulio Spagnoli, Denise Frosina, Nicole Hanson, Jodie Tassello and Achim A. Jungbluth. Cancer Immunity 2012

Research Trials

  • Primary Investigator: Starts 2012: A Multicentre, Randomized, Open-Label, Phase III Clinical Trial Of Gemcitabine And Carboplatin Followed By Epstein-Barr Virus-Specific Autologous Cytotoxic T Lymphocytes Versus Gemcitabine And Carboplatin As First Line Treatment For Advanced Nasopharyngeal Carcinoma Patients (JPEC Reference No: 11-13-0398)
  • Co-I: Starts Jan 2012: Phase III Multi-Centre Open-Label Randomised Controlled Trial of Selective Internal Radiation Therapy (SIRT) Vesus Sorafenib in Locally Advanced Hepatocellular Carcinoma (SIRveNIB)
  • Co-I: Starts Dec 08 ASCOT: Aspirin for Dukes C And High Risk Dukes B Colon Cancer – An International Multi-Centre, Double Blind, Randomized Placebo Controlled Phase III Trial (07-32-LGI)
  • Co-I: A Phase 1/2 Study of AZD6244 in Combination with Sorafenib in Advanced Hepatocellular Carcinoma
  • Co-I: Pyridoxine study for patients starting on capecitabine as single-agent chemo.
  • Co-I: Identification of potential biomarkers in early resectable hepatocellcular carcinoma
  • Co-I: Randomised Phase II Trial of Neoadjuvant Weekly Paclitaxel Plus Carboplatin Compared to Weekly Paclitaxel Alone Followed in Both Arms by Doxorubicin and Cyclophosphamide for Operable or Locally Advanced Basal-like Subtype Breast Cancer Correlating BRCA-1 mRNA and Protein Expression with Carboplatin Response