Clin Asst Prof Tan Wee Kiat Terence

​MBBS, FRCR (Clinical Oncology)(UK), FAMS

Senior Consultant

National Cancer Centre Singapore National Cancer Centre Singapore

Specialty: Radiation Oncology

Clinical Interests

Head & Neck, Uro-Oncology

Clinical Appointments

Visiting Consultant

NCCS Oncology Clinic @CGH

Academic Appointments

Clinical Asst Professor, Duke-NUS Medical School

About

Dr Tan is a Senior Consultant at the National Cancer Centre Singapore’s Division of Radiation Oncology. He is a graduate from the National University of Singapore and a Fellow of the Royal College of radiologist and a Fellow of the Academy of Medicine Singapore. Besides his local training, his clinical experience also comes from having had fellowships at the Mt Vernon Cancer Centre (UK), the Dr Daniel den Hoed Cancer Centre (Rotterdam), and the Gustav Roussy Institute (Paris). Dr Tan’s subspecialty interests are in Head & Neck and Uro- Oncology. He co-chair’s two of NCCS’ Cancer Service Line Development groups (Head & Neck, and Urology), and he is a Visiting Consultant to the Urology Departments in Singapore General Hospital and Changi General Hospital. Dr Tan is involved in clinical trials in Head & Neck, and in particular, Nasopharyngeal Cancers. Together with colleagues from the SGH Urology department, he pioneered the practice of Low Dose Rate Brachytherapy for Prostate Cancer in Singapore. High Dose Rate Brachytherapy for Prostate Cancer has since been added to the armamentarium of treatment options.

Education and Training

​MBBS, FRCR (Clinical Oncology)(UK), FAMS

Professional Appointments and Committee Memberships

  • ​Singapore Radiological Society, Member since 1989. Hon. Auditor 1998. 
  • Singapore Society of Oncology, Member since 1989. Treasurer 1999 & 2000. Organising chairman, ASM-AGM 2001.
  • Singapore General Hospital 150th Anniversary Celebrations, 1996. Celebrations for cancer survivors, Organising Committee, Secretary. 
  • UICC Workshop on Nasopharyngeal Cancer, 1998. Organising Committee, Chairman i/c Conference Facilities.
  • Concensus Conference on Uro-oncology, Singapore 1999. Organising committee 
  • Hepatobiliary subcommitee, National Cancer Centre 
  • Library committee, National Cancer Centre 
  • Head & neck data collection committee, National Cancer Centre 
  • Editorial Board, SingHealth Newsletter
  • Member, Advisory Committee on salt-cured and smoked food
  • Member, AM-SRS PET-CT guidelines sub-committee 
  • Member, Infection Control Committee, National Cancer Centre

Awards

  • ​Public Service Commission ‘Merit Bursary’ for Medicine, 1980
  • HMDP Fellowship for Radiotherapy (to attend The Royal College of Radiologists and to train under Professor Stanley Dische at the Mount Vernon Hospital Centre for Cancer Treatment, UK) September 1991 – October 1993, 1991
  • HMDP Fellowship in Radiation Oncology with special emphasis in Head and Neck, and Radiosurgery:
    Dept of Radiation Oncology, Dr Daniel den Hoed Cancer Centre, Rotterdam, Netherlands (3rd March – 5th May 1998)
    Leksell Gamma Knife Course, Elekta Instruments, Stockholm, Sweden and Graz University Hospital, Austria (8th June – 19th June 1998)
    Dept de Radiotherapie, Institut Gustave-Roussy, Villejuif Cedex, France (22nd June – 3rd September 1998), 1997
  • Best Poster (Varian Prize) ESTRO ’98, Edinburgh, 1998
  • Public Service Commission ‘Merit Bursary’ for Medicine, 1980
  • HMDP Fellowship for Radiotherapy (to attend The Royal College of Radiologists and to train under Professor Stanley Dische at the Mount Vernon Hospital Centre for Cancer Treatment, UK) September 1991 – October 1993, 1991
  • HMDP Fellowship in Radiation Oncology with special emphasis in Head and Neck, and Radiosurgery:
    Dept of Radiation Oncology, Dr Daniel den Hoed Cancer Centre, Rotterdam, Netherlands (3rd March – 5th May 1998)
    Leksell Gamma Knife Course, Elekta Instruments, Stockholm, Sweden and Graz University Hospital, Austria (8th June – 19th June 1998)
    Dept de Radiotherapie, Institut Gustave-Roussy, Villejuif Cedex, France (22nd June – 3rd September 1998), 1997
  • Best Poster (Varian Prize) ESTRO ’98, Edinburgh, 1998

Publications

  • Chua MLK, Hakansson AK, Ong EHW, Hong BH, Miao JJ, Sim AYL, Tan JSH, Tan KM, Lee GCJ, Low KP, Tuan JKL, Tan TWK, Wang MLC, Yeong JPS, Tan MCS, Lee LS, Kanesvaran R, Zhao X, Ho J, Spratt DE, Schaeffer EM, Tay KJ, Liu Y, Davicioni E, Khor LY.Transcriptomic analyses of localized prostate cancers of East Asian and North American men reveal race-specific luminal-basal and microenvironmental differences.Cancer Com-mun. 2023 Oct; 43(10):1164-1168 
  • Petit C, Lee A, Ma J, Lacas B, Ng WT, Chan ATC, Hong RL, Chen MY, Chen L, Li WF, Huang PY, Tan T, Ngan RKC, Zhu G, Mai HQ, Hui EP, Fountzilas G, Zhang L, Carmel A, Kwong DLW, Moon J, Bourhis J, Auperin A, Pignon JP, Blanchard P; MAC-NPC Collabora-tive Group.Role of chemotherapy in patients with nasopharynx carcinoma treated with radio-therapy (MAC-NPC): an updated individual patient data network meta-analysis.Lancet On-col. 2023 Jun; 24(6):611-623 
  • Poh SS, Tan BF, Yong FY, Fong KW, Wee JTS, Tan TWK, Chua MLK, Sommat K, Wang FQ, Soong YL.The impact of the COVID-19 pandemic on nasopharyngeal carcinoma pa-tients - a national cancer centre experience. Holist Integr Oncol. 2023 Jun; 2(1):17 
  • Ling ASM, Hankasson AK, Ong EHW, Lau ASY, Low KP, Wong TR, Tan N, Tan JSH, Tuan JKL, Tan TWK, Wang MLC, Tay KJ, Yeong JPS, Lee LS, Kanesvaran R, Tan MCS, Davi-cioni E, Khor LY, Chua MLK. Comparative genomic analyses between Asian and Caucasian prostate cancers in an 80,829 patient cohort. J Clin Oncol. 2022 Feb; 40(6_Suppl):273 
  • Li Y, Ong WS, Shwe MTT, Yit NLF, Quek SZH, Pang EPP, Looi WS, Nei WL, Wang MLC, Chua MLK, Tan TWK, Chua ET, Ng CT, Tuan JKL. Cardiovascular toxicities of androgen deprivation therapy in Asian men with localized pros-tate cancer after curative radiotherapy: a registry-based observational study. Cardiooncology. 2022 Mar; 8(1):4
  •  Lim VT, Gacasan AC, Tuan JKL, Tan TWK, Li Y, Nei WL, Looi WS, Lin X, Tan HQ, Chua EC, Pang EPP. Evaluation of inter- and intra-observer variations in prostate gland delineation using CT-alone versus CT/TPUS. Rep Pract Oncol Radiother. 2022 Mar; 27(1):97-103 
  • (68)Gallium-labelled PSMA-PET/CT as a diagnostic and clinical decision-making tool in Asian prostate cancer patients following prostatecto-my. Tan JSH, Goh CXY, Koh YS, Li Y, Tuan JKL, Chua ET, Tan TWK, Wang MLC, Lee LS, Tay KJ, Kanesvaran R, Toh CK, Tong AKT, Lam WWC, Chua MLK. Cancer Biol Med. 2019 Feb;16(1):157-166. doi: 10.20892/j.issn.2095-3941.2018.0288. 
  • Clinical and Dosimetric Predictors of Physician and Patient Reported Xerostomia Following Intensity Modulated Radiotherapy (IMRT) for Nasopharyngeal Cancer (NPC) – A Prospec-tive Cohort Analysis Sommat K, Hussain A, Ong WS, Yit NLF, Khoo JBK, Soong YL, Wee JTS, Fong KW, Tan TWK. Radiother Oncol. 2019 Jun 29;138:149-157. doi: 10.1016/j.radonc.2019.05.023. 
  • Comparison of radiomics tools for image analyses and clinical prediction in nasopharynx cancer. Liang ZG, Tan HQ, Zhang F, Rui Tan LK, Lin L, Lenkowicz J, Wang H, Wen Ong EH, Kusumawidjaja G, Phua JH, Gan SA, Sin SY, Ng YY, Tan TW, Soong YL, Fong KW, Park SY, Soo KC, Wee JT, Zhu XD, Valentini V, Boldrini L, Sun Y, Chua ML Br J Radiol. 2019 Oct;92(1102):20190271. doi: 10.1259/bjr.20190271. Epub 2019 Aug 27. 
  • 68Gallium-labelled PSMA-PET/CT as a diagnostic and clinical decision-making tool in Asian prostate cancer patients following prostatectomy Janice S.H. Tan, Charles X.Y. Goh, Yen Sin Koh, Youquan Li, Jeffrey K.L. Tuan, Eu Tiong Chua, Terence W.K. Tan, Michael L.C. Wang, Lui Shiong Lee6, Kae Jack Tay, Ravindran Kanesvaran, Chee Keong Toh, Aaron K.T. Tong, Winnie W.C. Lam, Melvin L.K. Chua Cancer Biol Med 2019. doi: 10.20892/j.issn.2095-3941.2018.0288 
  • Induction Chemotherapy plus Concurrent Chemoradiotherapy in Endemic Nasopharyngeal Carcinoma: Individual Patient Data Pooled Analysis of Four Randomized Tri-als. Clin Cancer Res. 2018 Apr 15;24(8):1824-1833. Epub 2018 Feb 5. Chen YP, Tang LL, Yang Q, Poh SS, Hui EP, Chan ATC, Ong WS, Tan T, Wee J, Li WF, Chen L, Ma BBY, Tong M, Tan SH, Cheah SL, Fong KW, Sommat K, Soong YL, Guo Y, Lin AH, Sun Y, Hong MH, Cao SM, Chen MY, Ma J. 
  • Prognostic Model for Stratification of Radioresistant Nasopharynx Carcinoma to Curative Salvage Radiotherapy. J Clin Oncol. 2018 Mar 20;36(9):891-899. Epub 2018 Feb 7. Li YQ, Tian YM, Tan SH, Liu MZ, Kusumawidjaja G, Ong EHW, Zhao C, Tan TWK, Fong KW, Sommat K, Soong YL, Wee JTS, Han F, Chua MLK. 
  • Thyroid V40 Predicts Primary Hypothyroidism After Intensity Modulated Radiation Therapy for Nasopharyngeal Carcinoma. Sommat K, Ong WS, Hussain A, Soong YL, Tan T, Wee J, Fong KW. Int J Radiat Oncol Biol Phys. 2017 Jul 1;98(3):574-580. doi: 10.1016/j.ijrobp.2017.03.007. Epub 2017 Mar 14. 
  • A 13-Year Single Institutional Experience with Definitive Radiotherapy in Hypopharyngeal Cancer. Sommat K, Yong SK, Fong KW, Tan TW, Wee JT, Soong YL. Ann Acad Med Singapore. 2017 Jan;46(1):32-36. 
  • Comparison of Circulating Tumour Cells and Circulating Cell-Free Epstein-Barr Virus DNA in Patients with Nasopharyngeal Carcinoma Undergoing Radiotherapy. Vo JH, Nei WL, Hu M, Phyo WM, Wang F, Fong KW, Tan T, Soong YL, Cheah SL, Sommat K, Low H, Ling B, Ng J, Tan WL, Chan KS, Oon L, Ying JY, Tan MH. Sci Rep. 2016 Dec;6(1):13. Epub 2016 Dec 19.