Clin Asst Prof Ng Yao Yi Kennedy

Dr Kennedy Ng is a Consultant Medical Oncologist at the National Cancer Centre Singapore, Clinical Assistant Professor at Duke-NUS Medical School, and Clinical Director at the Singapore General Hospital’s Division of Population Health and Integrated Care. He has a clinical and research interest in gastro-oesophageal, hepatobiliary, and pancreatic cancers.

His research bridges clinical care, policy and implementation, spanning health systems, health poli-cy and economics, and cancer screening and prevention. He leverages real-world data - from linked clinical registries, electronic health records and administrative datasets - to generate actionable evidence for service design, cost-effectiveness analyses, and policy evaluation. He has authored more than 30 peer-reviewed publications.

Dr Ng graduated MBBS (valedictorian) from the NUS Yong Loo Lin School of Medicine; obtained MRCP and MMed (NUS) in 2018; and received the Gordon Arthur Ransome Gold Medal. In 2022 he graduated as the top trainee of the Medical Oncology Specialist Programme. He was also awarded the Public Service Commission, Lee Kuan Yew Scholarship in 2024. As an Edward S. Mason and John F. Kennedy Fellow at the Harvard Kennedy School, he completed an MPA in 2025 and re-ceived the Raymond & Josephine Vernon Award for academic distinction and service.

He joined the SingHealth Internal Medicine Residency in 2016, served as Chief Resident (2018–2019), completed the Singapore Chief Resident Programme (2019), and received the Top Three SingHealth Chief Resident Award (2022). Passionate about reducing disparities in healthcare, he founded TriGen in 2020 to mobilise youth and community volunteers to support older adults.

• MPA (Harvard) 
• FAMS (S’pore) 
• MMed (Internal Medicine) (S’pore) 
• MRCP (UK) 
• MBBS (Hons) (S’pore)

• European Society of Medical Oncology, Member 
• Singapore Society of Oncology, Member 
• American Society of Clinical Oncology, Member 
• Society of Medical Decision Making, Member 
• NCCS Population Health Steering Committee, Secretariat Lead 
• SingHealth Internal Medicine Residency, Core Faculty 
• SingHealth Residency Leadership Programme, Core Faculty

• Raymond & Josephine Vernon Award for academic distinction and distinguished contribu-tion to the Edward S. Mason Program and Harvard Kennedy School (2025) 
• John F. Kennedy Fellow, Harvard Kennedy School (2025) 
• Lee Kuan Yew Scholarship, Public Service Commission, Singapore (2024)
• European Society of Medical Oncology, Leadership Generation Programme Awardee (Asia) (2022)
• Medical Oncology Exit Examination Book Prize (Top Trainee for Medical Oncology Specialist Examination) (2022)
• SingHealth Top 3 Chief Resident (2022)
• Singapore Health Quality Service Awards, HERO award (2021)
• SingHealth Medicine ACP Junior Educator Award (2021)
• SingHealth, Outstanding Resident Educator Award (RISE) (2021)
• SingHealth, Outstanding Resident Educator Award (RISE) (2019)
• G. A. Ransome Gold Medal (Top Candidate for Master of Medicine Internal Medicine) (2018)
• SingHealth, Outstanding Resident Award (RISE) (2018)
• SingHealth, Best House Officer (2017)
• Changi General Hospital, General Medicine Best House Officer (2017)
• Yong Loo Lin, Special Recognition Award (2017, 2019, 2020, 2021)
• Yong Loo Lin School of Medicine Dean’s List (2011-2016)
• AY2016 Lee Hsien Loong Award for Outstanding All-Round Achievement (2016)
• Lee Kuan Yew Gold Medal (2016)
• NUSS Medal for Outstanding Achievement (2016)
• Singapore Medical Association Medals (Silver) (2016)
• Gordon Arthur Ransome Medal and Prize in Internal Medicine (2016)
• Infectious Diseases Prize (2016)
• Lim Boon Keng Medal (2016)
• Wong Poi Kwong Medal (2016)
• Yeoh Khuan Joo Gold Medal and Prize (2016)
• Dermatological Society of Singapore Book Prize (2016)
• NSC-DSS VS Rajan Gold Medal and Book Prize (2016)
• Ivan Polunin Medal (2016)
• Nestle Nutrition Institute Prize (2016)
• Yong Loo Lin School of Medicine Excellence Awards (Leadership) (2015)
• Tan Choon Kim Book Prize (2014)
• Family Medicine Posting: 3rd Prize (2014)
• Robert Lin Memorial Medal (2013)
• Tan Choon Kim Medal (2012)
• Lee Foundation Professionalism Prize (2012)

• Cancer Screening, Early Detection, and Prevention 
• Health Economics and Health Policy 
• Gastro-Esophageal Cancer 
• Liver cancer 
• Biliary tract cancer 
• Pancreatic cancer

• Zhao JJ*, Ng Yao Yi Kennedy*, Sundar R, Klempner SJ. Checkpoint inhibitor benefit in perioperative gastro-esophageal cancer: A meta-analysis of phase III trials. Cancer Treatment Reviews. 2025;140:103002. doi:10.1016/j.ctrv.2025.103002 *Co-first authors. (IF 10.5) 
• Masuda, Y., Fong, K. L., Yeo, D., Yeo, C., Chue, K. M., Araba, S. B., Lim, C. W., Yeung, B., Lee, J., Lin, J., Chia, C., Ng, M., Kennedy Yao Yi Ng, Samol, J., Chia, D., Teh, J. L., Sundar, R., Yong, W. P., Tan, H. L., Mu-ro, K., … Tan, J. et al. Asia Pacific Gastroesophageal Cancer Congress (APGCC) 2024 consensus statement on stage 2 and 3 locally advanced gastric and Siewert 3 junctional adenocarcinoma. J Gastroenterol (2025). https://doi.org/10.1007/s00535-025-02266-4 (IF 6.9) 
• Anna Ho Yin Chan, Yun Zhao, Hwee Leong Tan, Darren Weiquan Chua, Kennedy Yao Yi Ng, Suat Ying Lee, Joycelyn Jie Xin Lee, David Tai, Brian Kim Poh Goh, Ye Xin Koh. Clinical Outcomes of Neoadjuvant Therapy Versus Upfront Surgery in Resectable Pancreatic Cancer: Systematic Review and Meta-analysis of Latest Randomized Controlled Trials. Ann Surg Oncol (2025). https://doi.org/10.1245/s10434-024-16674-y (IF 3.4) 
• Soh, N.H., Yau, C.R.Z., Low, X.Z., .. Kennedy Yao Yi Ng, et al. Prehabilitation Outcomes in Surgical Oncolo-gy Patients Undergoing Major Abdominal Surgery: A Meta-analysis of Randomized Control Trials. Ann Surg Oncol (2024). https://doi.org/10.1245/s10434-024-16527-8 (IF 3.4) 
• Ng Yao Yi Kennedy*, Teo AEK*, Tan SH, Tan JJE, Tay DSH, Lee AWX, Ang AJS, Wong LWJ, Choo SP, Toh HC, Lee SY, Lee JJX, Tai DW. Impact of Antibiotics and Chronic Medications on Efficacy of Immune Check-point Inhibitors in Patients With Hepatocellular Carcinoma. Asia Pac J Clin Oncol. 2024 Nov 27. doi: 10.1111/ajco.14139. Epub ahead of print. PMID: 39601254. *Co-first authors. 
• Kee W, Ng Yao Yi Kennedy, Liong SZ, Zhou S, Chee SK, Lim CW, Lam JYC, Tan JTH, Ong HS, Chan WH, et al. Real-World Outcomes for Localised Gastro-Oesophageal Adenocarcinoma Cancer Treated with Perioperative FLOT and Prophylactic GCSF Support in a Single Asian Centre. Cancers. 2024; 16(21):3697. https://doi.org/10.3390/cancers16213697 (IF: 5.2) *Co-first authors. 
• Jaryl Jia Hao Boey, Kennedy Yao Yi Ng, Cindy Krisnadi, Darren Wan-Teck Lim, Mei-Kim Ang, Response to fam-Trastuzumab-Deruxtecan in patients with metastatic HER2-positive salivary duct carcinoma: A case series, Oral Oncology, Volume 146, 2023, 106566, ISSN 1368-8375 (IF: 5.97) *Co-first authors.
• Ng Kennedy Yao Yi, Tan S, H, Tan J, J, E, Tay D, S, H, Lee A, W, X, Ang A, J, S, Wong L, W, J, Choo S, P, Tai D, W, -M, Lee J, J, X: Impact of Immune-Related Adverse Events on Efficacy of Immune Checkpoint In-hibitors in Patients with Advanced Hepatocellular Carcinoma. Liver Cancer 2021. doi: 10.1159/000518619 (IF: 12.43) 
• Ng Yao Yi Kennedy, Wong LWJ, Ang AJS, Lee AWX, Tay DSH, Tan JJE, Tan SH, Choo SP, Tai DW, Lee JJX. Immune checkpoint inhibitors and tyrosine kinase inhibitors in patients with advanced hepatocellular car-cinoma: Does the sequence matter? Asia Pac J Clin Oncol. 2022 Aug 10. doi: 10.1111/ajco.13837. Epub ahead of print. PMID: 35950298. (IF: 1.926) 
• Ng Kennedy Yao Yi, Chow EWX, Jiang B, Lim C, Goh BKP, Lee SY, Teo JY, Tan DMY, Cheow PC, Ooi LLPJ, Chow PKH, Lee JJX, Kam JH, Koh YX, Jeyaraj PR, Tan EK, Choo SP, Chan CY, Chung AYF, Tai D. Re-sected pancreatic adenocarcinoma: An Asian institution's experience. Cancer Rep (Hoboken). 2021 Oct;4(5):e1393. doi: 10.1002/cnr2.1393. Epub 2021 May 3. PMID: 33939335; PMCID: PMC8551988. (IF: 0.768) 
• Wanyi Kee*, Kennedy Yao Yi Ng*, Joycelyn Jie Xin Lee, Daniel Shao Weng Tan. Myasthenia gravis and my-ocarditis after administration of pembrolizumab in a patient with metastatic non-small cell lung cancer and re-sected thymoma. Clinical Lung Cancer, 2021. *Co-first authors. (IF: 4.84) 
• Ng Yao Yi Kennedy, Wong LWJ, Ang AJS, Tan SH, Choo SP, Tai DW, Lee JJX. Real-world efficacy and safe-ty of immune checkpoint inhibitors in advanced hepatocellular carcinoma: Experience of a tertiary Asian Center. Asia Pac J Clin Oncol. 2020 Sep 1. doi: 10.1111/ajco.13454. (IF: 2.601) 
• Ng Yao Yi Kennedy, Zhou S, Tan SH, Ishak NDB, Goh ZZS, Chua ZY, Chia JMX, Chew EL, Shwe T, Mok JKY, Leong SS, Lo JSY, Ang ZLT, Leow JL, Lam CWJ, Kwek JW, Dent R, Tuan J, Lim ST, Hwang WYK, Gri-va K, Ngeow J. Understanding the Psychological Impact of COVID-19 Pandemic on Patients With Cancer, Their Caregivers, and Health Care Workers in Singapore. JCO Glob Oncol. 2020 Oct;6:1494-1509. doi: 10.1200/GO.20.00374. (IF: 1.768) 
• Soundararajan A, Lim JX, Ngiam NHW, Tey AJ-Y, Tang AKW, Lim HA, … Ng Yao Yi Kennedy*. (2023) Smartphone ownership, digital literacy, and the mediating role of social connectedness and loneliness in im-proving the wellbeing of community-dwelling older adults of low socio-economic status in Singapore. PLoS ONE 18(8): e0290557. (IF: 3.75) *Corresponding author. 
• Goh, Z.Z.S., Ho, Mh.R., Ng Yao Yi Kennedy, et al. Using the Actor-Partner Interdependence Model to explore the psychological impact of COVID-19 on anxiety in dyads of patients with cancer and caregivers. Int.J. Behav. Med. (2023). (IF: 2.229) 
• Ngiam NHW, Yee WQ, Teo N, Yow KS, Soundararajan A, Lim JX, Lim HA, Tey A, Tang KWA, Tham CYX, Tan JPY, Lu SY, Yoon S, Ng Yao Yi Kennedy*, Low LL*. Building Digital Literacy in Older Adults of Low Socioeconomic Status in Singapore (Project Wire Up): Nonrandomized Controlled Trial. J Med Internet Res 2022;24(12):e40341. (IF: 7.08) *Co-corresponding author. 
• Lu SY, Yoon S, Yee WQ, Heng Wen Ngiam N, Ng KYY, Low LL. Experiences of a Community-Based Digital Intervention Among Older People Living in a Low-Income Neighborhood: Qualitative Study. JMIR Aging 2024;7:e52292. (IF: 4.9)