Clin Assoc Prof Yong Wei Sean

MBBS, FRCS (Gen Surg)(Glas), FRCS (Gen Surg)(Ed), FAMS

Deputy Chairman & Senior Consultant

National Cancer Centre Singapore National Cancer Centre Singapore

Specialty: Surgery & Surgical Oncology, General Surgery

Conditions Treated By This Doctor

Clinical Interests

Breast, Breast Surgery, Surgical Oncology

Clinical Appointments

Senior Consultant

Breast Surgery

Deputy Chairman & Senior Consultant

Division of Surgery & Surgical Oncology

Academic Appointments

Clinical Assoc Professor, Duke-NUS Medical School

About

Dr Yong Wei Sean graduated from NUS and subsequently trained in general surgery, obtaining FRCS in 1997. He developed a special interest in breast surgical oncology and did a fellowship in Toronto, Canada in 2002/03.

Dr Yong is currently practicing breast and general surgery, performing diagnostic breast biopsies, therapeutic breast cancer surgery including skin sparing mastectomy and sentinel lymph node biopsy. He also has interest in sentinel node biopsy for melanoma.

Education and Training

  • MBBS
  • FRCS (Gen Surg)(Glas)
  • FRCS (Gen Surg)(Ed)
  • FAMS

Professional Appointments and Committee Memberships

  • Senior Consultant, Surgical Oncology, NCCS 
  • Adjunct Associate Professor, NUS Yong Loo Lin School of Medicine 
  • Clinical Associate Professor, Duke-NUS Medical School 
  • Clinical Physician Faculty Member, SingHealth General Surgery Residency Programme

Awards

  • Singapore Health Quality Service Awards 2023 –Star Award 
  • Singapore Health Quality Service Awards 2022 –Star Award 
  • 2021 Long Service Medal (NCCS) 
  • 2020 Singapore Health Quality Service Awards 
  • 2019 Dean’s Award for Teaching Excellence in AY2018/2019 
  • Singapore Health Quality Service Awards 2018, Star Award 
  • NUS Special Recognition Award: Role Model to Medical Graduating Class of 2016 
  • 2014 Long Service Award (NCCS) – 20 years 
  • 2012-13 Best Tutor for Surgery (SGH) 
  • 2011-12 NUS Certificate of Award: Best Tutor for Surgery (SGH) 
  • 2010 Service With a Heart Award (SGH) 
  • 2008 Singapore Medical Journal: 2008 Recognition Award for Reviewing with Distinction 
  • 2008 Excellent Service Award (GOLD) 
  • 2007/ 2008 Dean’s Award for Teaching Excellence for Academic Year (NUS) 
  • 2007 Singapore Medical Journal: 2007 Recognition Award for Reviewing with Distinction 
  • 2007 HealthCare Humanity Award 
  • 2005 Sir James Fraser Travelling Fellowship (RCS Edinburgh) 
  • 2005 Minister for Health Award, Tsunami Relief, Indonesia 
  • 2002/3 HMDP (Ministry of Health) 
  • 1986-1987 ASEAN scholar  
  • AM Lead 3rd Cohort 2017/18 
  • HaPEE 4 modules (2016 – 2018)

Research Interests

  • Sentinel lymph node biopsy in breast cancer
  • Melanoma

Publications

  • Tan HJ, Tan PH, Leong LCH, et al. Encapsulated papillary carcinoma of the breast: An insti-tutional case series and literature review. Cancer Med. 2023;00:1-9. doi:10.1002/cam4.5855 
  • Lim JSH, Sim Y, Ngeow J, Yuen J, Tan VKM, Tan BKT, Yong WS, Wong CY, Lim SZ, Hamzah JLB, Tan SY, Wong FY, Madhukumar P. Male breast cancer: a Singapore perspec-tive. ANZ J Surg. 2022 Apr 25. doi: 10.1111/ans.17737. Epub ahead of print. PMID: 35470542. 
  • Ho PJ, Ho WK, Khng AJ, Yeoh YS, Tan BK, Tan EY, Lim GH, Tan SM, Tan VKM, Yip CH, Mohd-Taib NA, Wong FY, Lim EH, Ngeow J, Chay WY, Leong LCH, Yong WS, Seah CM, Tang SW, Ng CWQ, Yan Z, Lee JA, Rahmat K, Islam T, Hassan T, Tai MC, Khor CC, Yuan JM, Koh WP, Sim X, Dunning AM, Bolla MK, Antoniou AC, Teo SH, Li J, Hartman M. Overlap of high-risk individuals predicted by family history, and genetic and non-genetic breast cancer risk prediction models: implications for risk stratification. BMC Med. 2022 Apr 26;20(1):150. doi: 10.1186/s12916-022-02334-z. PMID: 35468796; PMCID: PMC9040206. 
  • Sim Y, Lim C, Phyu N, Tan KTB, Chew LST, Wong CY, Madhukumar P, Yong WS, Lim SZ, Hamzah JLB, Tan SY, Chay WY, Wong FY, Tan PH and Tan VKM. The Impact of Statin Use and Breast Cancer Recurrence - A Retrospective Study in Singapore. Front. Oncol. 12:835320. doi: 10.3389/fonc.2022.835320 
  • Lim JT, Koh JJE, Ho PJ, Liu J, Lim SH, Tan EY, Tan BKT, Tan VKM, Tan SM, Yong WS, Hartman M, Chen C. Impact of Subsidy on the Use of Personalized Medicine in Breast Can-cer. Value Health Reg Issues. 2022 Jan 29;29:108-115. doi: 10.1016/j.vhri.2021.10.002. Epub ahead of print. 
  • Bong TSH, Tan JKT, Ho JTS, Tan PH, Lau WS, Tan TM, Wong JSL, Tan VKM, Tan BKT, Madhukumar P, Yong WS, Lim SZ, Wong CY, Ong KW, Sim Y. Atypical Ductal Hyperplas-ia of the Breast on Core Needle Biopsy: Risk of Malignant Upgrade on Surgical Excision. J Breast Cancer. 2022 Feb;25(1):37-48. doi: 10.4048/jbc.2022.25.e7. PMID: 35199500; PMCID: PMC8876544. 
  • Chiam M, Ho CY, Quah E, Chua KZY, Ng CWH, Lim EG, Tan JRM, Wong RSM, Ong YT, Soong YL, Kwek JW, Yong WS, Loh KWJ, Lim C, Mason S, Krishna LKR. Changing self-concept in the time of COVID-19: a close look at physician reflections on social media. Philos Ethics Humanit Med. 2022 Jan 26;17(1):1. doi: 10.1186/s13010-021-00113-x. PMID: 35078488; PMCID: PMC8789479. 
  • Loo SY, Toh LP, Xie WH, Pathak E, Tan W, Ma S, Lee MY, Shatishwaran S, Yeo JZZ, Yuan J, Ho YY, Peh EKL, Muniandy M, Torta F, Chan J, Tan TJ, Sim Y, Tan V, Tan B, Madhukumar P, Yong WS, Ong KW, Wong CY, Tan PH, Yap YS, Deng LW, Dent R, Foo R, Wenk MR, Lee SC, Ho YS, Lim EH, Tam WL. Fatty acid oxidation is a druggable gateway regulating cellular plasticity for driving metastasis in breast cancer. Sci Adv. 2021 Oct 8;7(41):eabh2443. doi: 10.1126/sciadv.abh2443. Epub 2021 Oct 6. 
  • Choo PZQ, Loh AHL, Selvarajan S, Tan PH, Tan VKM, Yong WS, Leong LCH. Breast-related extranodal Rosai-Dorfman disease presenting as subcutaneous masses with thick hy-perechoic rim, with review of the literature. Breast J. 2021 Aug 31. doi: 10.1111/tbj.14286. Epub ahead of print. 
  • Lim SZ, Kusumawidjaja G, Mohd Ishak HM, Tan BKT, Tan SY, Hamzah JL, Madhukumar P, Yong WS, Wong CY, Sim Y, Lim GH, Lim SH, Tan SM, Wong FY, Tan VKM. Outcomes of Stage I and II Breast Cancer with Nodal Micrometastases Treated with Mastectomy with-out Axillary Therapy. Breast Cancer Res Treat. 2021 Oct;189(3):837-843. doi: 10.1007/s10549-021-06341-1. Epub 2021 Aug 3. 
  • CCY Ng,D Nasir, BN Loke, TKY Tay, AA Thike, V Rajasegaran, W Liu, JY Lee, P Guan, AH Lim, KTE C, MA Gudi, P Madhukumar, BKT Tan, VKM Tan, CY Wong, WS Yong, GH Ho, KW Ong, International Fibroepithelial Consortium, GWC Yip, BH Bay, P Tan, BT Teh, PH Tan. Genetic differences between benign phyllodes tumors and fibroadenomas re-vealed through targeted next generation sequencing. Modern Pathology. https://doi.org/10.1038/s41379-021-00787-w 
  • Hamzah JL, Tan BKT, Tan VKM, Preetha M, Lim SZ, Sim YR, Yong WS, Lee ZJ, Ong KW. A Pilot Study Comparing Sentimag/Sienna Versus Standard Modality for Sentinel Lymph Node Identification in Patients With Breast Cancer. Breast J. 2020 May; 26(5): 1074-1077 doi: 10.1111/tbj 13660 
  • Impact of hormonal status on ductal carcinoma in situ of the breast: Outcome and prognostic factors. Tay THC, Ng WY, Ong KW, Wong CY, Tan BKT, Yong WS, Madhukumar P, Tan VKM, Lim SZ, Sim Y Breast J. 2020; 26: 937– 945. https://doi.org/10.1111/tbj.13738 
  • Loke SY, P Munusamy, Koh GL, Chan CHT, P Madhukumar, Thung JL, Tan BKT, Ong KW, Yong WS, Sim Y, Oey CL, Lim SZ, Chan PMY, Ho JTS, Khoo JBK, Wong JSL, Thng CH, Chong BK, Tan EY, Tan VKM, Lee ASG. A circulating miRNA signature for stratification of breast lesions among women with abnormal screening mammograms (Manuscript). MDPI Cancers 2019 
  • Nasir NDM , Ng CCY, Rajasegaran V, Wong SF, Liu W, Ng GXP, Lee JY, Guan P, Lim JQ, Thike AA, Koh VCY, Loke BN, Chang KTE, Gudi MA, Lian DWQ, Madhukumar P, Tan BKT, Tan VK, Wong CY, Yong WS, Ho GH, Ong KW. Genomic characterisation of breast fibroepithelial lesions in an international cohort. International Fibroepithelial Consortium, Patrick Tan P, The BT, Tan PH. Journal of Pathology DOI: 10.1002/path.5333