Clin Assoc Prof Preetha Madhukumar

Dr Madhukumar is a Senior Consultant surgeon in Singhealth Duke-NUS Breast Centre under Divi-sion of Surgical Oncology. She obtained her MBBS and Master of Surgery degree from India. She obtained FRCS from Royal College of surgeons, Glasgow in 1998. She started working in Singapore from 1999 and obtained her FAMS and specialist accreditation in Surgery in 2004.

Since then she was working in Department of General Surgery, Singapore General Hospital (SGH) before joining National Cancer Centre Singapore, Department of Surgical Oncology. Her main in-terest is in breast cancer surgery including screening and detection, surgical management and follow up. She is also senior consultant in the trauma service under Division of General Surgery, SGH. Apart from the clinical interest she is very active in the educational field. She is a pioneer fellow of AMEI.

She is actively involved in teaching medical students, residents, fellows and allied health professionals. She is also actively involved in breast cancer research activities.

• FAMS; Academy of Medicine, Singapore, 2004 
• FRCS; Royal College of Surgeons, Glasgow, 1998 
• MS (General Surgery); Government Medical College, Trivandrum, Kerala University, 1993 
• M.B,B.S; Government Medical College, Trivandrum, Kerala University, 1990
  

• Programme Director, SingHealth Post-graduate Year 1(PGY1) Programme, SGH 
• Co-Chair, Joy at Surgical Services Workgroup 
• Deputy Vice-Chair, Undergraduate Education, DSSO 
• Chairperson, Wellbeing Committee, DSSO 
• College Master, DUKE NUS 
• Member, National ATLS Committee 
• Director, SingHeath ATLS Centre 
• Member, Graduate Medical Education Committee, SingHealth

• Singapore Health Quality Service Awards 2022 –Superstar Award (Clinician Merit) 
• Singapore Health Quality Service Awards 2020 
• Outstanding Faculty Award 2019/2020, Residency in SingHealth Excels (RiSE) Awards, Sep 2020 
• Service With A Heart Award Quality Service Award, SGH 2011 
• Outstanding Faculty for Advocacy (Surgery) Faculty Appreciation Award 2011 Duke NUS
• Care Excellence award, NCC 2011 
• NUS YLLSoM Clinical Faculty Scheme; Dean’s Award, NUS 2010/11

• SLN biopsy after neo adjuvant chemotherapy: Surgical trial 
• A multi-center, randomized, double-blinded, parallel group, placebo controlled trial to evaluate the efficacy and safety of activated recombinant factor VII (rFVII/NovoSeven/Niastase) in severely injured trauma patients with bleeding refractory to standard treatment

• Tan HJ, Tan PH, Leong LCH, Tan VKM, Tan BKT, Lim SZ, Preetha M, Wong CY, Yong WS, Sim Y. Encapsulated papillary carcinoma of the breast: An institutional case series and literature review. Cancer Med. 2023;00:1-9. doi:10.1002/cam4.5855 
• Tan HQ, Ong HH, Arjunan MK, Tan TJ, Tan RYC, Lee GSX, Lim EH, Ng R, Yeo RMC, Lim LFWT, Zhang Z, Yang CSH, Wong RX, Ooi GSK, Leong LCH, Tan SM, Madhukumar P, Sim Y, Tan VKM, Yeong J, Wong FY, Cai Y, Nei WL, JBCR, Ai3. Multi-center evaluation of artificial intelligent imaging and clinical models for predicting neoadjuvant chemotherapy response in breast cancer. Breast Cancer Research and Treatment https://doi.org/10.1007/s10549-022-06521-7 
• Hui Jun LIM, Lester Chee Hao LEONG, Yah Yuen TAN, Eugene Mun Wai ONG, Veronique Kiak Mien TAN, Sue Zann LIM, Evan Kok Yen WOO, Yien Sien LEE, Yirong SIM, Preetha MADHUKUMAR, Benita Kiat Tee TAN, Llewellyn Shao-jen SIM, Tammy Hui Lin MOEY, Thida WIN, Geok Hoon LIM. Savi Scout Wireless Localisation of the Breast and Axillary Lesions: Lessons Learned from Singapore's Early Experience. SMJ 2022 
• Sim Y, Lim C, Phyu N, Tan KTB, Chew LST, Wong CY, Madhukumar P, Yong WS, Lim SZ, Hamzah JLB, Tan SY, Chay WY, Wong FY, Tan PH and Tan VKM. The Impact of Statin Use and Breast Cancer Recurrence - A Retrospective Study in Singapore. Front. Oncol. 12:835320. doi: 10.3389/fonc.2022.835320 
• Loo SY, Toh LP, Xie WH, Pathak E, Tan W, Ma S, Lee MY, Shatishwaran S, Yeo JZZ, Yuan J, Ho YY, Peh EKL, Muniandy M, Torta F, Chan J, Tan TJ, Sim Y, Tan V, Tan B, Madhukumar P, Yong WS, Ong KW, Wong CY, Tan PH, Yap YS, Deng LW, Dent R, Foo R, Wenk MR, Lee SC, Ho YS, Lim EH, Tam WL. Fatty acid oxidation is a druggable gateway regulating cellular plasticity for driving metastasis in breast cancer. Sci Adv. 2021 Oct 8;7(41):eabh2443. doi: 10.1126/sciadv.abh2443. Epub 2021 Oct 6. 
• Lim SZ, Kusumawidjaja G, Mohd Ishak HM, Tan BKT, Tan SY, Hamzah JL, Madhukumar P, Yong WS, Wong CY, Sim Y, Lim GH, Lim SH, Tan SM, Wong FY, Tan VKM. Outcomes of Stage I and II Breast Cancer with Nodal Micrometastases Treated with Mastectomy with-out Axillary Therapy Breast Cancer Res Treat. 2021 Oct;189(3):837-843. doi: 10.1007/s10549-021-06341-1. Epub 2021 Aug 3 
• CCY Ng,D Nasir, BN Loke, TKY Tay, AA Thike, V Rajasegaran, W Liu, JY Lee, P Guan, AH Lim, KTE C, MA Gudi, P Madhukumar, BKT Tan, VKM Tan, CY Wong, WS Yong, GH Ho, KW Ong, International Fibroepithelial Consortium, GWC Yip, BH Bay, P Tan, BT Teh, PH Tan. Genetic differences between benign phyllodes tumors and fibroadenomas re-vealed through targeted next generation sequencing. Modern Pathology. https://doi.org/10.1038/s41379-021-00787-w 
• Wong FY, Wong RX, Zhou S, Ong WS, Pek PP, Yap YS, Tan BKT, Ngeow JYY, Tan VKM, Sim Y, Tan SM, Lim SH, Madhukumar P, Tan TJY, Loh KWJ, Ong MEH, Wong TH, Joint Breast. Effects of housing value and medical subsidy on treatment and outcomes of breast cancer patients in Singapore: A retrospective cohort study. Lancet. 2020 Dec 8; 6(100065). doi: https://doi.org/10.1016/j.lanwpc.2020.100065. 
• Tay THC, Ng WY, Ong KW, Wong CY, Tan BKT, Yong WS, Madhukumar P, Tan VKM, Lim SZ, Sim Y. Impact of hormonal status on ductal carcinoma in situ of the breast: Out-come and prognostic factors. Breast J. 2020; 26: 937– 945. https://doi.org/10.1111/tbj.13738 
• Loke SY, P Munusamy, Koh GL, Chan CHT, P Madhukumar, Thung JL, Tan BKT, Ong KW, Yong WS, Sim Y, Oey CL, Lim SZ, Chan PMY, Ho JTS, Khoo JBK, Wong JSL, Thng CH, Chong BK, Tan EY, Tan VKM, Lee ASG. A circulating miRNA signature for stratification of breast lesions among women with abnormal screening mammograms (Manuscript). MDPI Cancers 2019 
• Nasir NDM , Ng CCY, Rajasegaran V, Wong SF, Liu W, Ng GXP, Lee JY, Guan P, Lim JQ, Thike AA, Koh VCY, Loke BN, Chang KTE, Gudi MA, Lian DWQ, Madhukumar P, Tan BKT, Tan VK, Wong CY, Yong WS, Ho GH, Ong KW. International Fibroepithelial Consor-tium, Patrick Tan P, The BT, Tan PH. Genomic characterisation of breast fibroepithelial le-sions in an international cohort. Journal of Pathology DOI: 10.1002/path.5333 12. Hamzah JLB, Tan BKT, Tan VK, Madhukumar P, Lim SZ, Sim Y, Yong WS, Lee ZJ, Ong KW. A pilot study comparing Sentimag/Sienna versus standard modality for sentinel lymph node identification in patients with breast cancer. The Breast Journal Oct 2019 DOI: 10.1111/tbj.13660 
• Sim Y, Ng GXP, Ng CCY, Rajasegaran V, Wong SF, Liu W, Guan P, Nagarajan S, Ng WY, Thike AA, Lim JCT, Nasir NDB, Tan VK, Madhukumar P, Yong WS, Wong CY, Tan BKT, Ong KW, The BT, Tan PH. A Novel Genomic Panel as an Adjunctive Diagnostic Tool for the Characterization and Profiling of Breast Fibroepithelial Lesions (Manuscript). BMC Medical Genomics (Open) Oct 2019 
• Sim Y, Tan VKM, Sidek NAB, Chia DKA, Tan BKT, Madhukumar P, Yong WS, Wong CY, Ong KW. Bilateral breast cancers in an Asian population, and a comparison between syn-chronous and metachronous tumours. ANZ J Surg. 2018 Oct; 88(10): 982-987. doi: 10/1111/ans.14773. Epub 2018 Aug 23. 
• Ng YY, Tan VK, Pek WS, Chang JH, Sim Y, Ong KW, Yong WS, Madhukumar P, Wong CY, Ong YS, Tan BK, Tan BKT. Surgical and oncological safety of nipple-sparing mastec-tomy in an Asian population. Breast Cancer. Breast Cancer. 2019 Mar; 26(2): 165-171. doi: 10.1007/s12282-018-0908-y. Epub 2018 Sep 14.