Lim Geok Hoon, Lim Swee Ho, Lee Jung Ah, Pang Siyan Jinne, Tan Qing Ting, Yan Ziyan

Axillary management of breast cancer patients with isolated chest wall recurrence after mastectomy

Abstract Disclosures
Abstract:
Breast cancer is the most common cancer affecting women worldwide. Despite advances in medical treatment, isolated loco-regional breast cancer recurrences can still occur at a rate of 10-35%. In patients with treatable isolated local chest wall recurrence after mastectomy, the NCCN guidelines on the axillary management of those patients are unclear. Though sentinel lymph node biopsy (SLNB) is possible and may be considered, there is limited data on its usefulness. We aimed to determine if axillary restaging surgery was required in this group of patients who developed operable isolated chest wall recurrences after mastectomy. We had recently published our results for KKH patients and found that axilla restaging surgery can be safely omitted with no increased axillary recurrences on medium term follow-up. WE hope to further validate our findings by carrying out a retrospective multicenter study to recruit more patients.
In this study, patients with bilateral cancers, concurrent regional or distant metastases, patients without surgery for their chest wall recurrences will be excluded. The demographics, pathological data and second recurrences will be collected from the database and compared between patients with axillary lymph node dissection (ALND), SLNB and no axillary operation.

We aim to determine if axillary restaging surgery was required in this group of patients who developed operable isolated invasive chest wall recurrences after mastectomy.

Joint Breast Cancer Registry Singapore