Back To Search Results

Prof Teoh Tiong Ghee

MD, MSc, MRCPI, FRCOG

Senior Consultant

KK Women's and Children's Hospital

Specialty: Obstetrics ＆ Gynaecology

Clinical Interest: Maternal Fetal Medicine

Clinical Appointments

Director, Maternal and Child Global Health and Care Transformation Division of Obstetrics ＆ Gynaecology KK Women's and Children's Hospital
Senior Consultant Obstetrics ＆ Gynaecology KK Women's and Children's Hospital

Profile

Education

FRCOG 2006
MD 1997
Maternal & Fetal Medicine Subspecialist University of Toronto 1996
Subspecialist Maternal & Fetal Medicine 1996
MRCPI 1993
MRCOG 1992
MSc 1991 Trinity College, University of Dublin
MB BCh BAO 1987 Royal College of Surgeons, National University of Ireland

Professional Appointments and Committee Memberships

Professor of Obstetrics, Imperial College London

Awards

Research Interests

Publications

Microbial-driven preterm labour involves crosstalk between the innate and adaptive immune response.
Chan D, Bennett PR, Lee YS, Kundu S, Teoh TG, Adan M, Ahmed S, Brown RG, David AL, Lewis HV, Gimeno-Molina B, Norman JE, Stock SJ, Terzidou V, Kropf P, Botto M, MacIntyre DA, Sykes L.
Nat Commun. 2022 Feb 21;13(1):975. doi: 10.1038/s41467-022-28620-1.
PMID: 35190561
Direct on-swab metabolic profiling of vaginal microbiome host interactions during pregnancy and preterm birth.
Pruski P, Correia GDS, Lewis HV, Capuccini K, Inglese P, Chan D, Brown RG, Kindinger L, Lee YS, Smith A, Marchesi J, McDonald JAK, Cameron S, Alexander-Hardiman K, David AL, Stock SJ, Norman JE, Terzidou V, Teoh TG, Sykes L, Bennett PR, Takats Z, MacIntyre DA.
Nat Commun. 2021 Oct 13;12(1):5967. doi: 10.1038/s41467-021-26215-w.
PMID: 34645809
The interaction between vaginal microbiota, cervical length, and vaginal progesterone treatment for preterm birth risk.
Kindinger LM, Bennett PR, Lee YS, Marchesi JR, Smith A, Cacciatore S, Holmes E, Nicholson JK, Teoh TG, MacIntyre DA.
Microbiome. 2017 Jan 19;5(1):6.
Relationship between vaginal microbial dysbiosis, inflammation, and pregnancy outcomes in cervical cerclage.
Kindinger LM, MacIntyre DA, Lee YS, Marchesi JR, Smith A, McDonald JA, Terzidou V, Cook JR, Lees C, Israfil-Bayli F, Faiza Y, Toozs-Hobson P, Slack M, Cacciatore S, Holmes E, Nicholson JK, Teoh TG, Bennett PR.
Sci Transl Med. 2016 Aug 3;8(350):350ra102. doi: 10.1126/scitranslmed.aag1026
The effect of gestational age and cervical length measurements in the prediction of spontaneous preterm birth in twin pregnancies: an individual patient level meta-analysis.
Kindinger LM, Poon LC, Cacciatore S, MacIntyre DA, Fox NS, Schuit E, Mol BW, Liem S, Lim AC, Serra V, Perales A, Hermans F, Darzi A, Bennett P, Nicolaides KH, Teoh TG.
BJOG. 2016 May;123(6):877-84. doi: 10.1111/1471-0528.13575. Epub 2015 Sep 1. Review.PMID:26333191
READ MORE:
Pregnancy and neonatal outcomes in COVID-19: study protocol for a global registry of women with suspected or confirmed SARS-CoV-2 infection in pregnancy and their neonates, understanding natural history to guide treatment and prevention.
Banerjee J, Mullins E, Townson J, Playle R, Shaw C, Kirby N, Munnery K, Bourne T, Teoh TG, Dhanjal M, Poon L, Wright A, Lees C.
BMJ Open. 2021 Jan 29;11(1):e041247. doi: 10.1136/bmjopen-2020-041247.
PMID: 33514576
Rapid quality improvement in a preterm birth clinic care pathway during the COVID-19 pandemic.
Zarasvand S, Bayar E, Adan M, Mountain K, Lewis H, Joash K, Teoh TG, Bennett PR, Das S, Sykes L.
BMJ Open Qual. 2020 Dec;9(4):e001049. doi: 10.1136/bmjoq-2020-001049.
PMID: 33372041
First Trimester Circulating MicroRNA Biomarkers Predictive of Subsequent Preterm Delivery and Cervical Shortening.
Cook J, Bennett PR, Kim SH, Teoh TG, Sykes L, Kindinger LM, Garrett A, Binkhamis R, MacIntyre DA, Terzidou V.
Sci Rep. 2019 Apr 10;9(1):5861. doi: 10.1038/s41598-019-42166-1
Cerclage position, cervical length and preterm delivery in women undergoing ultrasound indicated cervical cerclage: A retrospective cohort study.
Cook JR, Chatfield S, Chandiramani M, Kindinger L, Cacciatore S, Sykes L, Teoh T, Shennan A, Terzidou V, Bennett PR.
PLoS One. 2017 Jun 1;12(6)
Vaginal progesterone prophylaxis for preterm birth (the OPPTIMUM study): a multicentre, randomised, double-blind trial.
Norman JE, Marlow N, Messow CM, Shennan A, Bennett PR, Thornton S, Robson SC, McConnachie A, Petrou S, Sebire NJ, Lavender T, Whyte S, Norrie J; OPPTIMUM study group.
Lancet. 2016 May 21;387(10033):2106-16. doi: 10.1016/S0140-6736(16)00350-0. Epub 2016 Feb 24. PMID:26921136
Sulfasalazine augments a pro-inflammatory response in interleukin-1β-stimulated amniocytes and myocytes.
Sykes L, Thomson KR, Boyce EJ, Lee YS, Rasheed ZB, MacIntyre DA, Teoh TG, Bennett PR.
Immunology. 2015 Dec;146(4):630-44. doi: 10.1111/imm.12534. Epub 2015 Nov 3. PMID:26395271
The vaginal microbiome during pregnancy and the postpartum period in a European population.
MacIntyre DA, Chandiramani M, Lee YS, Kindinger L, Smith A, Angelopoulos N, Lehne B, Arulkumaran S, Brown R, Teoh TG, Holmes E, Nicoholson JK, Marchesi JR, Bennett PR.
Sci Rep. 2015 Mar 11;5:8988. doi: 10.1038/srep08988. PMID:25758319
Management of hypertriglyceridaemia-induced acute pancreatitis in pregnancy.
Amin T, Poon LC, Teoh TG, Moorthy K, Robinson S, Neary N, Valabhji J.
J Matern Fetal Neonatal Med. 2015 May;28(8):954-8. doi: 10.3109/14767058.2014.939064. Epub 2014 Aug 5. PMID:25072837
Characterization of neutrophil subsets in healthy human pregnancies.
Ssemaganda A, Kindinger L, Bergin P, Nielsen L, Mpendo J, Ssetaala A, Kiwanuka N, Munder M, Teoh TG, Kropf P, Müller I.
PLoS One. 2014 Feb 13;9(2):e85696. doi: 10.1371/journal.pone.0085696.
Anti-inflammatory prostaglandins for the prevention of preterm labour, Reproduction In Press.
Sykes L, Macintyre DA, Teoh TG, Bennett PR, 2014
The CRTH2 agonist Pyl A prevents lipopolysaccharide-induced fetal death but induces preterm labour.
Sykes L, Herbert BR, Macintyre DA, Hunte E, Ponnampalam S, Johnson MR, Teoh TG, Bennett PR. Immunology. 2013 Jul;139(3):352-65. doi: 10.1111/imm.12085
Chemoattractant receptor homologous to the T helper 2 cell (CRTH2) is not expressed in human amniocytes and myocytes.
Sykes L, Lee Y, Khanjani S, Macintyre DA, Yap XJ, Ponnampalam S, Teoh TG, Bennett PR.
PLoS One. 2012;7(11):e50734. doi: 10.1371/journal.pone.0050734. Epub 2012 Nov 30.
Time interval from elective removal of cervical cerclage to onset of spontaneous labour.
Alabi-Isama L, Sykes L, Chandiramani M, Patel S, Rai R, Bennett PR, Teoh TG.
Eur J Obstet Gynecol Reprod Biol. 2012 Dec;165(2):235-8. doi: 10.1016/j.ejogrb.2012.09.005. Epub 2012 Sep 25.
The Th1:th2 dichotomy of pregnancy and preterm labour.
Sykes L, MacIntyre DA, Yap XJ, Teoh TG, Bennett PR.
Mediators Inflamm. 2012;2012:967629. doi: 10.1155/2012/967629. Epub 2012 Jun 7. Review.
Changes in the Th1:Th2 cytokine bias in pregnancy and the effects of the anti-inflammatory cyclopentenone prostaglandin 15-deoxy-Δ(12,14)-prostaglandin J2.
Sykes L, MacIntyre DA, Yap XJ, Ponnampalam S, Teoh TG, Bennett PR.
Mediators Inflamm. 2012;2012:416739. doi: 10.1155/2012/416739. Epub 2012 May 29.
Nuclear factor kappa B activation occurs in the amnion prior to labour onset and modulates the expression of numerous labour associated genes.
Lim S, MacIntyre DA, Lee YS, Khanjani S, Terzidou V, Teoh TG, Bennett PR.
PLoS One. 2012;7(4):e34707. doi: 10.1371/journal.pone.0034707. Epub 2012 Apr 2.
Prevention of preterm labour via the modulation of inflammatory pathways
Macintyre DA, Sykes L, Teoh TG, Bennett PR
J Matern Fetal Neonatal Med. 2012 Mar 13
Targeting immune activation in the prevention of pre-term labor, US Obstetrics and Gynecology, Sykes L, Macintyre DA, Teoh TG, et al., 2011, Vol:6, ISSN:1754-6168, Pages:103-109
Endocrine problems in pregnancy
Amin A, Robinson S, Teoh TG
Postgrad Med J. 2011 Feb : 87 (1024) : 116-24. Epub 2010 Nov 16
Obesity in Pregnancy: a major healthcare issue
Tsoi E, Shaikh H, Robinson S, Teoh TG
Postgrad Med J. 2010 Oct:86 (1020): 617-23
Ultrasound-indicated cerclage for prevention of preterm delivery in primiparas following treatment of cervical intraepithelial neoplasia
Taher SE; Chandiramani M; Soutter P; Arulkumaran S; Eliahoo J; Teoh T; Hassan S; McIndoe A; Shennan A; Bennett PR. (09 Sep 2009). OP25.05:. Ultrasound Obstet Gynecol. 34:144-144.
Management of maternal obesity prior to and during pregnancy.
Shaikh H, Robinson S, Teoh TG.
Semin Fetal Neonatal Med. 2009 Nov 27 Epub ahead of print PMID: 19945927
Anorectal symptoms during pregnancy: how important is trimester?
Unadkat SN, Leff DR, Teoh TG, Rai R, Darzi AW, Ziprin P.
Int J Colorectal Dis. 2010 Mar;25(3):375-9.PMID: 19921218
A randomized controlled trial of cervical scanning vs history to determine cerclage in women at high risk of preterm birth (CIRCLE trial).
Simcox R, Seed PT, Bennett P, Teoh TG, Poston L, Shennan AH.
Am J Obstet Gynecol. 2009 Jun;200(6):623.e1-6. Epub 2009 Apr 19.PMID: 19380124
Vitamin D deficiency and supplementation during pregnancy.
Yu CK, Sykes L, Sethi M, Teoh TG, Robinson S.
Clin Endocrinol (Oxf). 2009 May;70(5):685-90. Epub 2008 Sep 2.PMID: 18771564
A cost-effectiveness analysis of delayed sphincteroplasty for anal sphincter injury.
Tan EK, Jacovides M, Khullar V, Teoh TG, Fernando RJ, Tekkis PP.
Colorectal Dis. 2008 Sep;10(7):653-62. Epub 2008 Mar 15.PMID: 18355373
The effect of restorative proctocolectomy on sexual function, urinary function, fertility, pregnancy and delivery: a systematic review.
Cornish JA, Tan E, Teare J, Teoh TG, Rai R, Darzi AW, Paraskevas P, Clark SK, Tekkis PP.
Dis Colon Rectum. 2007 Aug;50(8):1128-38. Review.PMID: 17588223
Arginase activity mediates reversible T cell hyporesponsiveness in human pregnancy.
Kropf P, Baud D, Marshall SE, Munder M, Mosley A, Fuentes JM, Bangham CR, Taylor GP, Herath S, Choi BS, Soler G, Teoh TG, Modolell M, Müller I.
Eur J Immunol. 2007 Apr;37(4):935-45.PMID: 17330821
Laparoscopic versus open colposuspension for urodynamic stress incontinence.
Tan E, Tekkis PP, Cornish J, Teoh TG, Darzi AW, Khullar V.
Neurourol Urodyn. 2007;26(2):158-69. Review.PMID: 17252603
A meta-analysis on the influence of inflammatory bowel disease on pregnancy.
Cornish J, Tan E, Teare J, Teoh TG, Rai R, Clark SK, Tekkis PP.
Gut. 2007 Jun;56(6):830-7. Epub 2006 Dec 21. Review.PMID: 17185356
Obesity in pregnancy.
Yu CK, Teoh TG, Robinson S.
BJOG. 2006 Oct;113(10):1117-25. Epub 2006 Aug 10. Review.PMID: 16903839
Glucose production in the human placenta.
Leonce J, Brockton N, Robinson S, Venkatesan S, Bannister P, Raman V, Murphy K, Parker K, Pavitt D, Teoh TG, Regan L, Burchell A, Steer P, Johnston DG.
Placenta. 2006 Apr;27 Suppl A:S103-8. Review.PMID: 16618444
Expression of Gsalpha, connexion-43, connexion-26, and EP1, 3 and 4 receptor myometrium of prelabor singleton versus multiple gestations & the effects of mechanical stretch & steroids on Gsalpha
Lyall F, Lye S, Teoh TG, Robson S. J Soc Gynecol Investig. 2002. Sep-Oct;9(5):299-307.
Uterine artery Doppler in predicting pregnancy outcome in women with antiphospholipid syndrome.
Venkat-Raman N, Backos M, Teoh TG, Lo WT, Regan L.
Obstet Gynecol. 2001 Aug;98(2):235-42.PMID: 11506839
Congenital absence of portal vein in the fetus: a case report.
Venkat-Raman N, Murphy KW, Ghaus K, Teoh TG, Higham JM, Carvalho JS.
Ultrasound Obstet Gynecol. 2001 Jan;17(1):71-5.PMID: 11244661
Umbilical artery blood flow velocity in pregnancies complicated by systemic lupus erythematosus.
Farine D, Granovsky-Grisaru S, Ryan G, Seaward PG, Teoh TG, Laskin C, Ritchie JW.
J Clin Ultrasound. 1998 Oct;26(8):379-82.PMID: 9783243
Corticotropin-releasing hormone and proopiomelanocortin-derived peptides are present in human myometrium.
Clifton VL, Telfer JF, Thompson AJ, Cameron IT, Teoh TG, Lye SJ, Challis JR.
J Clin Endocrinol Metab. 1998 Oct;83(10):3716-21.PMID: 9768689 [PubMed - indexed for
The role of fetal karyotyping from unconventional sources
Teoh TG, Ryan G, Johnson J, Winsor EJ.
Am J Obstet Gynecol. 1996 Oct;175(4 Pt 1):873-7.PMID: 8885739
The management of female infertility by tubal microsurgical reconstruction: a ten year review.
Teoh TG, Kondaveeti U, Darling MR.
Ir J Med Sci. 1995 Jul-Sep;164(3):212-4.PMID:
Investigations of vascular responses of human umbilical vessels in normal and pre-eclamptic pregnancies Breslin E, Teoh T G, Docherty J R.
Clinical Experimental Hypertension. Pt. B: Hypertension in Pregnancy 1993; (3): 463-75.
Amniotomy in labor
Teoh TG, Robson MS, Boylan PC
N Eng J Med. 1993 Sep 16; 329 (12): 886-7
Ultrasound diagnosis of occipito-posterior position in labour
Fitzpatrick C F, Teoh TG, Darling MR
J Obstet Gnaecol 1992; 12: 281-2
Measurement of amniotic fluid volume in early labour is a useful admission test.
Teoh TG, Gleeson RP, Darling MR.
Br J Obstet Gynaecol. 1992 Oct;99(10):859-60. PMID: 1420003
Snuffles in infants--infection or autonomic dysfunction.
Teoh TG, Fox GP, Matthews TG.
Ir J Med Sci. 1992 Feb;161(2):44-5.PMID: 1517053
Tattoos in pregnant women; an important clinical sign.
Fitzpatrick C, Teoh TG, Darling MR.
Ir Med J. 1991 Dec-1992 Jan;84(4):130-1. PMID: 1817122

Research Trials

GRACE: Global Research Consortium of Artificial Intelligence in Cardiotocography (CTG) for Enhanced Maternal-Fetal Outcome

Tags: Obstetrics ＆ Gynaecology, Maternal Fetal Medicine