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Vinorelbine (Oral)

Drug Class: Commonly Known As: Category:
Vinca Alkaloid Navelbine® Cancer-related

Vinorelbine (Oral) - What is it for

It is a medicine used in the treatment of certain types of cancer e.g. non-small cell lung cancer and advanced breast cancer.

Vinorelbine (Oral) - Side Effects, Precautions, and Contraindications

What side effects can Vinorelbine (Oral) cause?

  • Nausea and vomiting
    There are medicines available, which may prevent or decrease these side effects. If you are given these medicines, take them as directed.
  • Constipation with abdominal cramping
  • Mild to moderate fatigue or weakness
  • Muscle pain
  • Decreased white blood cells, red blood cells and platelets
    This may increase your chances of getting infections, bruising or bleeding and feeling tired.
  • Temporary hair loss may occur several weeks after treatment
  • Numbness, tingling or burning sensation on fingers and toes may occur after several treatments

Inform your doctor if any of the following occurs:

  • Fever of 38°C or higher, sore throat, severe mouth sore
  • Unusual bruising, bleeding or black tarry stools
  • Chest pain, sudden onset or gradual worsening of cough or breathlessness
  • Severe constipation not relieved by laxatives, with severe abdominal pain
  • Yellowing of the eyes or skin and dark tea-coloured urine
  • Allergic reaction e.g. rashes, facial swelling

Before taking Vinorelbine (Oral), what precautions must I follow?

  • Inform your doctor or pharmacist if you:
      • Have any other medical conditions e.g. heart problems.
      • Are taking any long-terms medicines or supplements, and if you plan to start any new ones.
      • Plan to have any vaccination or just had one, especially yellow fever vaccination.
  • Effective birth control measures are recommended for both men and women during and up to 3 months after treatment with Vinorelbine. Inform your doctor if you plan to or suspect that you are pregnant.
  • Do not breastfeed while taking Vinorelbine. Inform your doctor if you have any intentions to.

What food or medicine must I avoid when I take Vinorelbine (Oral)?

Vinorelbine (Oral) - Dosage and How to Use

How should Vinorelbine (Oral) be used?

It is a capsule taken by mouth, after food and swallowed whole with water. Do not chew or suck the capsule. Take the exact number of capsules, according to the schedule instructed by your doctor.

If vomiting occurs soon after a dose, please check with your doctor if you require a repeat dose.

What should I do if I miss a dose?

​If you miss a dose of Vinorelbine, contact your doctor for further instructions on what to do.

What should I do if I overdose?

​If you overdose on this medicine, inform your doctor immediately.

Vinorelbine (Oral) - Handling and Storage

How should I handle Vinorelbine (Oral) safely?

Do not crush, chew or suck the capsule.

How should I store Vinorelbine (Oral)?

Keep away from children;#Keep in a cool, dry place, away from direct sunlight;#Store in the refrigerator. Do not freeze.;#

How should I dispose of Vinorelbine (Oral) safely?

Vinorelbine (Oral) - Additional Information

  • Updated on Tuesday, October 17, 2017
  • This article is contributed by Department of Pharmacy National Cancer Centre Singapore

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