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Lugol's Iodine (for MIBG scan)

Drug Class: Commonly Known As: Category:
Anti-Thyroid Medicine Lugol's Iodine Adult, Children

Lugol's Iodine (for MIBG scan) - What is it for

​This medication is used to protect the thyroid gland after radioactive iodine treatment or during medical scans using radioisotopes such as MIBG scans. The medication works by blocking the thyroid gland from absorbing the radioactive iodine into the thyroid.

This medication may also be used to prepare the thyroid gland for surgical removal, and to treat certain overactive thyroid conditions (e.g. hyperthyroidism, thyroid storm).

Lugol's Iodine (for MIBG scan) - Side Effects, Precautions, and Contraindications

What side effects can Lugol's Iodine (for MIBG scan) cause?

​Common side effects include:

  • Nausea, vomiting, stomach discomfort
  • Diarrhoea
  • Metallic taste, burning or pain in the mouth, increased salivation

Rare but serious side effects include:

  • Severe abdominal pain
  • Severe nausea, vomiting or diarrhoea

The symptoms of a drug allergy include one or more of the following:

  • Swollen face, eyes, lip, tongue
  • Difficulty in breathing
  • Itchy skin rashes over your whole body

If you experience any of these symptoms, you should stop your medication and see your healthcare professional immediately.

Before taking Lugol's Iodine (for MIBG scan), what precautions must I follow?

​Inform your healthcare professional if:

  • You are allergic to potassium iodide, iodine or any of the other ingredients of this medication
  • You are pregnant, or planning to become pregnant or breastfeeding
  • You have severe problems with your kidneys
  • You are taking any other medications, including supplements, traditional medications and herbal remedies

What food or medicine must I avoid when I take Lugol's Iodine (for MIBG scan)?

​Some medications should also be avoided prior to MIBG scan. These include amlodipine, nifedipine, salbutamol, oxymetazoline, pseudoephedrine, promethazine, tramadol, caffeine, and certain antipsychotics.

This list is non-exhaustive, do consult your doctor or pharmacist for more information.

Lugol's Iodine (for MIBG scan) - Dosage and How to Use

How should Lugol's Iodine (for MIBG scan) be used?

The usual dose of Lugol’s iodine is a very small amount, measure the correct dose carefully using the 1mL-syringe supplied by pharmacist. Further dilute the measured dose with water, juice or milk before administering, to improve the taste and minimize stomach upset.

For MIBG scan: This medication should be started 1 day before your MIBG  dye injection and continued for a total of 5 days.

Routine schedule for MIBG scan:
Sunday: Start Lugol’s Iodine solution and continue for a total of 5 days
Monday: MIBG dye injection
Tuesday: Rest day
Wednesday and Thursday: MIBG scan

What should I do if I miss a dose?

​If you forget to take a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose. Then take your next dose at the usual time. Do not take two doses to make up for the missed dose.

What should I do if I overdose?

Lugol's Iodine (for MIBG scan) - Handling

How should I handle Lugol's Iodine (for MIBG scan) safely?

Lugol's Iodine (for MIBG scan) - Storage

How should I store Lugol's Iodine (for MIBG scan)?

Keep away from children;#Keep in a cool, dry place, away from direct sunlight;#Store at room temperature;#

How should I dispose of Lugol's Iodine (for MIBG scan) safely?

​Pack this medication into a black trash bag and seal it tightly before throwing into the rubbish chute or bin.

Lugol's Iodine (for MIBG scan) - Additional Information

  • Updated on Wednesday, March 24, 2021
  • Article contributed by Pharmacy Department KK Women's and Children's Hospital

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