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Lenvatinib

Drug Class: Commonly Known As: Category:
Multi-Kinase Inhibitor Lenvima® Cancer-related

Lenvatinib - What is it for

Lenvatinib is a medication used to treat certain types of advanced cancers e.g. thyroid, kidney and liver.

Lenvatinib - Side Effects, Precautions, and Contraindications

What side effects can Lenvatinib cause?

  • Nausea, vomiting, diarrhea or stomach discomfort
  • Decreased appetite and weight loss
  • Tiredness
  • Headache
  • Joint and muscle ache
  • Palms of the hands or soles of the feet may become numb, sore, red or dry
  • Increased blood pressure
    Monitor your blood pressure closely. Discuss a proper follow-up plan with your doctor.
  • Mouth sore or ulcer
    Keep your mouth clean by brushing your teeth and rinsing your mouth after every meal.
  • Voice hoarseness

Inform your doctor if any of the following occurs:

  • Rapid heartbeat or chest pain or shortness of breath
  • Sudden swelling of both legs and feet
  • Yellowing of the eyes or skin and dark-tea coloured urine
  • Unusual weakness, tiredness or light-headedness
  • Pain while urinating
  • Unusual muscle cramps or numbness
  • Severe diarrhea, nausea, vomiting or abdominal pain
  • Signs of unusual bleeding: bruising, black sticky stools

Before taking Lenvatinib, what precautions must I follow?

  • Inform your doctor or pharmacist if you have any other medical conditions e.g. heart problems, high blood pressure.
  • Do not take medications and supplements without informing your doctor or pharmacist.
  • Use effective birth control during and for at least one month after stopping treatment with Lenvatinib. Inform your doctor if you or your partner, plan for or suspect pregnancy.

What food or medicine must I avoid when I take Lenvatinib?

Lenvatinib - Dosage and How to Use

How should Lenvatinib be used?

Lenvatinib is taken once daily at about the same time, with or without food.
It should be swallowed whole with water. If you have difficulty swallowing the capsules, inform your doctor or pharmacist.

What should I do if I miss a dose?

If you miss a dose of Lenvatinib, take it as soon as you can if it is within 12 hours of the missed dose. However if more than 12 hours have passed, skip the missed dose and go back to your usual dosing time. Do not double the dose.

What should I do if I overdose?

If you overdose on this medication, inform your doctor immediately.

Lenvatinib - Handling and Storage

How should I handle Lenvatinib safely?

Do not crush, chew or open the capsules.

How should I store Lenvatinib?

Keep away from children;#Keep in a cool, dry place, away from direct sunlight;#Store at room temperature;#

How should I dispose of Lenvatinib safely?

Lenvatinib - Additional Information

  • Updated on Tuesday, September 25, 2018
  • This article is contributed by Department of Pharmacy National Cancer Centre Singapore

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