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COVID-19 Vaccination for NCCS Patients

Vaccination guidelines for people with cancer

According to the latest Ministry of Health guidelines, COVID-19 vaccination is recommended for cancer patients, including those on active cancer treatment.

All the categories below apply to Pfizer-BioNTech/Comirnaty, Moderna and Sinovac-CoronaVac COVID-19 vaccines, based on data currently available. These recommendations may change as more data becomes available locally and globally.

Allow Vaccination

​Active cancer not on treatment with chemotherapy, radiotherapy or immunotherapy CAN be vaccinated at any available vaccination site.

Active cancer not on treatment is defined as:

a) Not on any treatment in the past 3 months AND

b) No planned treatment in the next 2 months.

​Persons on cancer hormonal therapy CAN be vaccinated at any available vaccination site.
​Persons with a history of cancer, who are in remission, CAN be vaccinated at any available vaccination site.

​Persons on active cancer treatment:

  • Chemotherapy
  • Radiation therapy or
  • Immunotherapy

CAN be considered for vaccination, after assessment by their primary oncologist on the eligibility. The primary oncologist will write a memo which the patient can take along with them to any available vaccination site to get vaccinated.


If you are a NCCS patient, there are two ways to get the COVID-19 vaccination:

i) If you are currently NOT on active cancer treatment with chemotherapy, radiation therapy or immunotherapy, you should register at www.vaccine.gov.sg for vaccination at any available vaccination site as part of the national COVID-19 vaccination programme.

Patients on endocrine therapy alone, can also register for vaccination at any available vaccination site .

ii) If you ARE CURRENTLY on active cancer chemotherapy, radiation therapy or immunotherapy (OR have received these treatments in the past 3 months or planned to receive these treatments in the next 2 months), and wish to be vaccinated, please seek your doctor’s advice at your next NCCS outpatient clinic consultation. Your doctor will discuss with you the risk and benefits of COVID-19 vaccination while you are on active cancer treatment and assess your eligibility to have the vaccination based on your clinical condition. If assessed to be eligible and you wish to proceed with vaccination, your doctor will write you a memo which you can take along to any available vaccination site to get vaccinated.

Frequently Asked Questions

  1. Why do cancer patients need to take three doses of the COVID-19 vaccine as part of their initial vaccination?

    Cancer patients may have a blunted immune response to vaccination, and may not develop good protection against the virus with two vaccine doses. There is evidence that they would benefit from a third dose of the vaccine as it helps to develop a more protective immune response.

    Three doses of COVID-19 vaccination are recommended by the Ministry of Health for persons who are immunocompromised (e.g. cancer patients on active treatment with chemotherapy and immunosuppressive therapy) as part of the enhanced primary vaccination course.

    Cancer patients should receive a third dose of the vaccine two months after their second dose as part of an enhanced primary vaccine course of vaccination.

    With the high number of cases in the community, cancer patients are encouraged to get vaccinated. Vaccination can reduce the risk of severe complications or death from COVID-19 infection, and this is particularly important for cancer patients who may be at higher risk should infection occur.

  2. I am currently on active cancer treatment - how and when should I get the third dose?

    For persons who are immunocompromised, it is recommended that you receive a third dose of the same mRNA vaccine you received for the first two doses. The third dose of the vaccine should be taken two months after your second dose.

    Please consult your doctor about the optimal timing of your vaccination if you are on active cancer treatment.

  3. I am currently on active cancer treatment and waiting for my treatment to be completed before taking my third dose. What precautions should I take?

    Patients who are on active cancer treatment can take COVID-19 vaccines safely. However, your doctor may sometimes advise delaying vaccination to a time when the vaccine may be more effective (e.g. after completion of aggressive cancer treatment).  Please discuss with your doctor on the optimal timing of your third dose.

    While waiting to get your vaccination, you are strongly advised to avoid crowded places where the risk of exposure to infection is high, and to strictly adhere to safe management measures, such as wearing a face mask, frequent handwashing with soap, safe distancing, only going out for essentials, using TraceTogether and seeking prompt medical attention if feeling unwell.

  4. I have completed three doses of the COVID-19 vaccine as part of my initial vaccination. Do I need to receive a fourth booster dose?

    Cancer patients who are immunocompromised and have completed the 3-dose enhanced primary vaccination series are recommended to receive a fourth booster dose of a mRNA vaccine, six months later.

    Please discuss with your doctor on the optimal timing of your fourth booster dose.
    * All individuals aged 30 years and above are recommended to receive a booster dose. Refer to MOH FAQs for more information.

  5. Does my fourth booster dose have to be of the same brand as my first three doses? Is it safe to mix vaccines?

    The Expert Committee on COVID-19 Vaccination has recommended that for the booster dose, the two mRNA vaccines (Pfizer-BioNTech or Moderna) can be used interchangeably, regardless of which one was taken for the initial three doses.

     

    General questions on safety and efficacy of vaccines for cancer patients

            
  6. Why is the COVID-19 vaccination now being recommended for cancer patients, including those currently on cancer treatment?
             
    The Ministry of Health, Chapters of Medical Oncologists & Radiation Oncologists, College of Physicians of the Academy of Medicine, Singapore; and international guidelines recommend cancer patients, including those currently on active cancer treatment get COVID-19 vaccination. 

    This is because cancer patients are at increased risk of severe complications from COVID-19 infection. Vaccination protects cancer patients against COVID-19 infection and can reduce the risk of severe complications, should infection occur.

    In addition to vaccination, which is an important measure, patients should strictly adhere to safe management measures, such as wearing mask, frequent handwashing with soap, only going out for essentials, using TraceTogether and seeking prompt medical attention if feeling unwell.

  7. How do we know that COVID-19 vaccines are safe for cancer patients?

    There is currently no evidence of any safety signals or increased rates of adverse events from mRNA-based COVID-19 vaccines for cancer patients.


  8. What are the risks and benefits of getting COVID-19 vaccination?

    Cancer patients are at increased risk of severe complications from COVID-19 infections. Vaccination protects patients against COVID-19 infection and can reduce the risk of severe complications, should infection occur.

    Please seek your doctor’s advice at your next NCCS outpatient clinic consultation. Your doctor will discuss with you the risk and benefits of COVID-19 vaccination while you are on active cancer treatment and assess your eligibility to have the vaccination based on your clinical condition.

  9. How should I get COVID-19 vaccination if I am currently on active cancer treatment?

    At your next NCCS outpatient clinic consultation, please consult your doctor about COVID-19 vaccination. Your doctor will discuss with you the risk and benefits of vaccination while you are on active cancer treatment and assess your eligibility to have the vaccination based on your clinical condition. If assessed to be eligible, your doctor will write you a memo which you can take along to any available vaccination site to get vaccinated.

  10. Can I choose which COVID-19 vaccine I take?

    National Vaccination Centres currently use either the Pfizer-BioNTech/Comirnaty, Moderna and Sinovac-CoronaVac COVID-19 vaccines, which are approved by MOH. Each vaccination site will only administer one type of COVID-19 vaccine.

  11. Will I get a vaccination certificate?          

    A printed card will be given to you after your first and second vaccinations. In addition, you can access your vaccination records via Singpass online on Health Hub.

    Healthcare professionals (e.g. doctors at the hospitals, polyclinics and GPs) taking care of you can access your vaccination records through the National Electronic Health Records (NEHR) system.

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