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Home > For Researchers > Research Publications
 
Research Publications
 
1. Boyle P, Ariyaratne MA, Barrington R, Bartelink H, Bartsch G, Berns A, de Valeriola D, Dinshaw KA, Eggermont AM, Gray N, Kakizoe T, Karki BS, Kaslar M, Kerr DJ, Khayat D, Khuhaprema T, Kim IH, Martin-Moreno J, McVie G, Park JG, Philip T, Ringborg U, Rodger A, Seffrin Jr, Semiglazov V, Soo KC, Sun YT, Thomas R, Tursz T, Veronesi U, Wiestler O, Yoo KY, Zatonski W, Zhao P (2006) Tobacco: deadly in any form or disguise. Lancet 367(9524) : 1710-1712 (Impact factor:23.407)
2. Quek R, Lim ST, Tan EH (2006) Pneumoperitoneum following percutaneous lung biopsy. Lancet 368(9549) : 1794 (Impact factor:23.407)
3. Low WK, Toh ST, Wee J, Fook-Chong SM, Wang DY (2006) Sensorineural hearing loss after radiotherapy and chemoradiotherapy: a single, blinded, randomized study. J Clin Oncol 24(12) : 1904-1909 (Impact factor:11.81)
4. Toh CK, Gao F, Lim WT, Leong SS, Fong KW, Yap SP, Hsu AA, Eng P, Koong HN, Thirugnanam A, Tan EH (2006) Never-smokers with lung cancer: epidemiological evidence of a distinct disease entity. J Clin Oncol 24(15) : 2245-2251 (Impact factor:11.81)
5. Toh HC, Teo M, Ong KW, Lee V, Chan E, Lee AS, Vathsala A (2006) Use of sirolimus for Epstein-Barr virus-positive smooth-muscle tumour. Lancet Oncol 7(11) : 955-957 (Impact factor:7.855)
6. Chia WK, Lim YL, Greaves MW, Ang P (2006) Toxic epidermal necrolysis in patient with breast cancer receiving letrozole. Lancet Oncol 7(2) : 184-185 (Impact factor:7.855)
7. Hettinger K, Vikhanskaya F, Poh MK, Lee MK, de Belle I, Zhang JT, Reddy SA, Sabapathy K (2006) c-Jun promotes cellular survival by suppression of PTEN. Cell Death Differ 14(2) : 218-29 (Impact factor:7.785)
8. Bundy JG, Iyer NG, Gentile MS, Hu De, Kettunen M, Maia AT, Thorne NP, Brenton JD, Caldas C, Brindle KM (2006) Metabolic consequences of p300 gene deletion in human colon cancer cells. Cancer Res 66(15) : 7606-7614 (Impact factor:7.616)
9. Aggarwal A, Guo DL, Hoshida Y, Yuen ST, Chu KM, So S, Boussioutas A, Chen X, Bowtell D, Aburatani H, Leung SY, Tan P (2006) Topological and Functional Discovery in a Gene Co-expression Meta-Network of Gastric Cancer. Cancer Res 66(1) : 232-241 (Impact factor:7.616)
10. Ou K, Kesuma D, Ganesan K, Yu K, Soon SY, Lee SY, Goh XP, Hooi M, Chen W, Jikuya H, Ichikawa T, Kuyama H, Matsuo E, nishimura O, Tan P (2006) Quantitative profiling of drug-associated proteomic alterations by combined 2-nitrobenzenesulfenyl chloride (NBS) isotope labeling and 2DE/MS identification. J Proteome Res 5(9) : 2194-2206 (Impact factor:6.901)
11. Leong CT, Ong CK, Tay SK, Huynh H (2006) Silencing expression of UO-44 (CUZD1) using small interfering RNA sensitizes human ovarian cancer cells to cisplatin in vitro. Oncogene 26(6) : 870-880 (Impact factor:6.872)
12. Chin SF, Wang Y, Thorne NP, Teschendorff AE, Pinder SE, Vias M, Naderi A, Roberts I, Barbosa-Morais NL, Garcia MJ, Iyer NG, Kranjac T, Robertson JF, Aparicio S, Tavare S, Ellis I, Brenton JD, Caldas C (2006) Using array-comparative genomic hybridization to define molecular portraits of primary breast cancers. Oncogene 2006 Sep 25 : Epub ahead of print (Impact factor:6.872)
13. Iyer NG, Xian J, Chin SF, Bannister AJ, Daigo Y, Aparicio S, Kouzarides T, Caldas C (2006) p300 is required for orderly G1/S transition in human cancer cells. Oncogene 2006 Jul 31 : Epub ahead of print (Impact factor:6.872)
14. Zhang DW, Jeang KT, Lee CGL (2006) P53 negatively regulates the expression of FAT10, a gene upregulated in various cancers. Oncogene 25(16) : 2318-2327 (Impact factor:6.872)
15. Siddique MM, Sabapathy K (2006) Trp53-dependent DNA-repair is affected by the codon 72 polymorphism. Oncogene 25(25) : 3489-3500 (Impact factor:6.872)
16. Phang BH, Sabapathy K (2006) The codon 72 polymorphism-specific effects of human p53 are absent in mouse cells: Implications on generation of mouse models. Oncogene 2006 Nov 20 : Epub ahead of print (Impact factor:6.872)
17. Ong CK, Leong C, Tan PH, Van T, Huynh H (2006) The role of 5’ untranslated region in translational suppression of OKL38 mRNA in hepatocellular carcinoma. Oncogene 2006 Aug 21 : Epub ahead of print (Impact factor:6.872)
18. Xiang X, Jada SR, Li HH, Fan L, Tham LS, Wong CI, Lee SC, Lim R, Zhou QY, Goh BC, Tan EH, Balram C (2006) Pharmacogenetics of OATP-C (SLC21A6) gene and the impact of *1b and *15 haplotypes on irinotecan disposition in Asian cancer patients. Pharmacogenet Genomics 16(9) : 683-691 (Impact factor:5.882)
19. Ren J, Kan A, Leong SH, Ooi LL, Jeang KT, Chong SS, Kon OL, Lee CG (2006) Fat10 plays a role in the regulation of chromosomal stability. J Biol Chem 281(16) : 11413-11421 (Impact factor:5.854)
20. Gough DJ, Sabapathy K, Ko EY, Arthur HA, Schreiber RD, Trapani JA, Clarke CJ, Johnstone RW (2007) A novel c-Jun-dependent signal transduction pathway necessary for the transcriptional activation of interferon gamma response genes. J Biol Chem 282(2) : 938-946 (Impact factor:5.854)
21. Balram C, Jada SR, Lim DWT (2006) Correspondence re: Cecchin et al., Carboxylesterase isoform 2 mRNA expression in peripheral blood mononuclear cells is a predictive marker of the irinotecan to SN38 activation step in colorectal cancer patients. Clin Cancer Res 2005;11:6901-7. Clin Cancer Res 12(6) : 1942 (Impact factor:5.715)
22. Yao X, Qian CN, Zhang ZF, Tan MH, Kort EJ, Yang XJ, Resau JH, Teh BT (200 ) Two distinct types of blood vessels in clear cell renal cell carcinoma have contrasting prognostic implications. Clin Cancer Res 13(1) : 161-169 (Impact factor:5.715)
23. Huynh H, Soo KC, Chow PK, Panasci L, Tran E (2006) Xenografts of human hepatocellular carcinoma: a useful model for testing drugs. Clin Cancer Res 12(14 Pt 1) : 4306-4314 (Impact factor:5.715)
24. Yu K, Ganesan K, Miller LD, Tan P (2006) A modular analysis of breast cancer reveals a novel low-grade molecular signature in estrogen receptor-positive tumors. Clin Cancer Res 12(11 Pt 1) : 3288-3296 (Impact factor:5.715)
25. Lim DWT, Jada SR, Balram C (2006) Correspondence re: Cecchin E et al., Carboxylesterase Isoform 2 mRNA Expression in Peripheral Blood Mononuclear Cells is a Predictive Marker of the Irinotecan to SN38 Activation Step in Colorectal Cancer Patients. Clin Cancer Res 11 : 6901-6907 (Impact factor:5.715)
26. Lim SG, Wai CT, Lee YM, Dan YY, Sutedja DS, Wee A, Suresh S, Wu YJ, Machin D, Lim CC, Fock KM, Koay E, Bowden S, Locarnini S, Ishaque SM (2006) A randomized, placebo-controlled trial of thymosin-alpha1 and lymphoblastoid interferon for HbeAg-positive chronic hepatitis B. Antivir Ther 11(2) : 245-253 (Impact factor:5.286)
27. Lal S, Rao Jada S, Xiang X, Lim WT, Lee EJ, Balram C (2006) Pharmacogenetics of target genes across the warfarin pharmacological pathway. Clin Pharmacokinet 45(12) : 1189-1200 (Impact factor:5.195)
28. Huynh H, Soo KC, Chow PK, Tran E (2007) Targeted inhibition of the extracellular signalregulated kinase kinase pathway with AZD6244 (ARRY-142886) in the treatment of hepatocellular carcinoma.. Mol Cancer Ther 6(1) : 138-46 (Impact factor:5.171)
29. Ty A, See SJ, Khoo JBK, Rao J, Wong MC (2006) Oligodendroglial tumor chemotherapy using “decreased-dose-intensity” PCV: a singapore experience. Neurology 66(2) : 247- 249 (Impact factor:4.947)
30. Fong CL, Mok CL, Hui KM (2006) Intramuscular immunization with plasmid coexpressing tumour antigen and Flt-3L results in potent tumour regression. Gene Ther 13(3) : 245- 256 (Impact factor:4.836)
31. Oh WK, Tay MH, Huang J (2007) Is there a role for platinum chemotherapy in the treatment of patients with hormone-refractory prostate cancer?. Cancer 109(3) : 477-86 (Impact factor:4.8)
32. Olivo M, Ali-Seyed M (2007) Apoptosis signalling mechanisms in human cancer cells induced by Calphostin-PDT.. Int J Oncol 30(3) : 537-48 (Impact factor:4.7)
33. Tong WM, Lee MK, Galendo D, Wang ZQ, Sabapathy K (2006) Aflatoxin-B exposure does not lead to p53 mutations but results in enhanced liver cancer of Hupki (human p53 knock-in) mice. Int J Cancer 23 Mar 2006 : Epub ahead of print (Impact factor:4.7)
34. Lai PS, Cheah PY, Kadam P, Chua CL, Lie DK, Li HH, Eu KW, Seow-Choen F, Lee AS (2006) Overexpression of RB1 transcript is significantly correlated with 13q14 allelic imbalance in colorectal carcinomas. Int J Cancer 119(5) : 1061-1066 (Impact factor:4.7)
35. Marcom PK, Isaacs C, Harris L, Wong ZW, Kommarreddy A, Novielli N, Mann G, Tao Y, Ellis MJ (2006) The combination of letrozole and trastuzumab as first or second-line biological therapy produces durable responses in a subset of HER2 positive and ER positive advanced breast cancers. Breast Cancer Res Treat 2006 Aug 8 : Epub ahead of print (Impact factor:4.643)
36. Wong NS, Kahn HJ, Zhang L, Oldfield S, Yang LY, Marks A, Trudeau Me (2006) Prognostic significance of circulating tumour cells enumerated after filtration enrichment in early and metastatic breast cancer patients. Breast Cancer Res Treat 99(1) : 63-69 (Impact factor:4.643)
37. Wang B, Wang B, Ngoi S, Wang J, Chong SS, Lee CG (2006) The promoter region of the MDR1 gene is largely invariant, but different single nucleotide polymorphism haplotypes affect MDR1 promoter activity differently in different cell lines. Mol Pharmacol 70(1) : 267-276 (Impact factor:4.612)
38. Chong VF, Zhou JY, Khoo JB, Chan KL, Huang J (2006) Correlation between MR imagingderived nasopharyngeal carcinoma tumor volume and tNM system. Int J Radiat Oncol Biol Phys 64(1) : 72-76 (Impact factor:4.556)
39. Kang KB * Wang TT, * Woon CT, * Cheah ES, * Moore XL, * Zhu C,, Wang TT. Woon CT, Cheah ES, Moore XL, Zhu C, Wong MC (2007) # Wang TT, # Woon CT, # Cheah ES, # Moore XL, # Zhu C, # Wang TT, # Enhancement of glioblastoma radioresponse by a selective COX-2 inhibitor celecoxib: inhibition of tumor angiogenesis with extensive tumor necrosis.. Int J Radiat Oncol Biol Phys 67(3) : 888-96 (Impact factor:4.556)
40. Goh AS, Chung AY, Lo RH, Lau TN, Yu SW, Chng M, Satchithanantham S, Loong SL, Ng DC, Lim BC, Connor S, Chow PK (2007) A novel approach to brachytherapy in hepatocellular carcinoma using a phosphorous(32) ((32)P) brachytherapy delivery device-a first-in-man study.. Int J Radiat Oncol Biol Phys 67(3 : 786-92 (Impact factor:4.556)
41. Whiteman M, Chu SH, Siau JL, Rose P, Sabapathy K, Schantz JT, Cheung NS, Spencer JP, Armstrong JS (2007) The pro-inflammatory oxidant hypochlorous acid induces bax-dependent mitochondrial permeabilisation and cell death through AIF-/EndoG-dependent pathways.. Cell Signal 19(4) : 705-714 (Impact factor:4.398)
42. Deyrup AT, Lee VK, Hill CE, Cheuk W, Toh HC, Kesavan S, Chan EW, Weiss SW (2006) Epstein-Barr virus-associated smooth muscle tumors are distinctive mesenchymal tumors reflecting multiple infection events: a clinicopathologic and molecular analysis of 29 tumors from 19 patients. Am J Surg Pathol 30(1) : 75-82 (Impact factor:4.377)
43. Cao X, Eu KW, Kumarasinghe MP, Li H, Loi C, Cheah PY (2006) Mapping of hereditary mixed polyposis syndrome (HMPS) to chromosome 10q23 by genomewide high-density single nucleotide polymorphism (SNP) scan and identification of BMPR1A loss of function. J Med Genet 43(3) : e13 (Impact factor:4.33)
44. Wong AS, Soo RA, Lu JJ, Loh KS, Tan KS, Hsieh WS, Shakespeare TP, Chua ET, Lim HL, Goh BC (2006) Paclitaxel, 5-fluorouracil and hydroxyurea concurrent with radiation in locally advanced nasopharyngeal carcinoma. Ann Oncol 17(7) : 1152-1157 (Impact factor:4.319)
45. Soo R, Wu J, Aggarwal A, Tao Q, Hsieh W, Putti T, Tan K, Soon W, Lai Y, Mow B, Hsu S, Loh K, Tan L, Tan P, Goh BC (2006) Celecoxib reduces microvessel density in patients treated with nasopharyngeal carcinoma and induces changes in gene expression.. Ann Oncol 17(11): 1625-1630 (Impact factor:4.319)
46. Rodrigues F, Sarkar-Tyson M, Harding SV, Sim SH, Chua HH, Lin CH, Han X, Karuturi RK, Sung K, Yu K, Chen W, Atkins TP, Titball RW, Tan P (2006) A Global Map of Growth Regulated Gene Expression in Burkholderia pseudomallei, the Causative Agent of Melioidosis. J Bacteriol 2006 Sep 22 : Epub ahead of print (Impact factor:4.167)
47. Ihrlund LS, Hernlund E, Viktorsson K, Panaretakis T, Barna G, Sabapathy K, Linder S, Shoshan MC (2006) Two distinct steps of Bak regulation during apoptotic stress signaling: Different roles of MEKK1 and JNK1. Exp Cell Res 7 Mar 2006 : Epub ahead of print (Impact factor:4.148)
48. Soo KC, Wee J, Tan EH (2006) Reply: Surgery vs chemoRT for locally advanced operable head and neck cancers. Br J Cancer 94(10) : 1546-1547 (Impact factor:4.115)
49. Krubasik D, Iyer NG, English WR, Ahmed AA, Vias M, Roskelley C, Brenton JD, Caldas C, Murphy G (2006) Absence of p300 induces cellular phenotypic changes characteristic of epithelial to mesenchyme transition. Br J Cancer 95(2) : 245 (Impact factor:4.115)
50. Wang Z, Sew PH, Ambrose H, Ryan S, Chong SS, Lee EJ, Lee CG (2006) Nucleotide sequence analyses of the MRP1 gene in four populations suggest negative selection on its coding region. BMC Genomics 7 : 111 (Impact factor:4.092)
51. Jaichandran S, Yap ST, Khoo AB, Ho LP, Tien SL, Kon OL (2006) In Vivo Liver Electroporation: Optimization and Demonstration of Therapeutic Efficacy. Hum Gene Ther 2 Feb 2006 : Epub ahead of print (Impact factor:4.079)
52. Wang GY, Ho IA, Sia KC, Miao L, Hui KM, Lam PY (200 ) Engineering of an improved cell cycle regulatable HSV-1 amplicon vector with enhanced transgene expression in proliferating cells yet attenuated activities in resting cells. Hum Gene Ther Mar 200 : epub ahead of print (Impact factor:4.079)
53. Lim LC, Tan MH, Eng C, Teh BT, Rajasoorya RC (2006) Thymic carcinoid in multiple endocrine neoplasia 1: genotype-phenotype correlation and prevention. J Intern Med 259(4) : 428-432 (Impact factor:4.04)
54. Gao F, Tan SB, Machin D, Wong NS (2007) Confirmation of double-peaked time distribution of mortality for Asian breast cancer patients in a population-based study.. Breast Cancer Res 9(2) : R21[Epub] (Impact factor:4.026)
55. Chen W, Salto-Tellez M, Palanisamy N, Ganesan K, Hou Q, Tan LK, Sii LH, Ito K, Tan B, Wu J, Tay A, Tan KC, Ang E, Tan BK, Tan PH, Ito Y, Tan P (2007) Targets of genome copy number reduction in primary breast cancers identified by integrative genomics.. Genes Chromosomes Cancer 46(3) : 288-301 (Impact factor:3.937)
56. Lee CI, Leong SH, Png AE, Choo KW, Syn C, Lim DT, Law Hy, Kon OL (2006) An isothermal method for whole genome amplification of fresh and degraded DNA for comparative genomic hybridization, genotyping and mutation detection. DNA Res 13(2) : 77-88 (Impact factor:3.896)
57. Thong PSP, Olivo M, Kho KW, Harris M, Soo KC Laser Confocal Endomicroscopy as a Novel Technique for Fluorescence Diagnostic Imaging of the Oral Cavity. J Biomed Opt 12(1) : 014007 (Impact factor:3.557)
58. Yap KPL, Ang P, Lim IHK, Ho GH, Lee ASG (2006) Detection of a novel Alu-mediated BRCA1 exon 13 duplication in Chinese breast cancer patients and implications for genetic testing. Clin Genet 70(1) : 80-82 (Impact factor:3.276)
59. Thumboo J, Wee HL, Cheung YB, Machin D, Luo N, Fong KY (2006) Development of a Smiling Touchscreen multimedia program for HRQoL assessment in subjects with varying levels of literacy. Value Health 9(5) : 312-319 (Impact factor:3.211)
60. Zhou Y, Tang K, Law HY, Ng IS, Lee CGL, Chong SS (2006) FMR1 CGG repeat patterns and flanking haplotypes in three Asian populations and their relationship with repeat instability. Ann Hum Genet 70(Pt 6) : 784-796 (Impact factor:3.192)
61. Goh BK, Ooi LL, Tan YM, Cheow PC, Chung YF, Chow PK, Wong WK (2006) Clinico-pathological features of cystic pancreatic endocrine neoplasms and a comparison with their solid counterparts. Eur J Surg Oncol 32(5) : 553-556 (Impact factor:3.184)
62. Toh CK, Gao F, Lim WT, Leong SS, Fong KW, Yap SP, Hsu AA, Eng P, Koong HN, Thirugnanam A, Tan EH (200 ) Differences between small-cell lung cancer and non-small-cell lung cancer among tobacco smokers.. Lung Cancer 2007 Jan 30 : Epub ahead of print (Impact factor:3.172)
63. Ang BT, Wong J, Lee KK, Wang E, Ng I (2006) Temporal changes in cerebral tissue oxygenation with cerebrovascular pressure reactivity in severe traumatic brain injury. J Neurol Neurosurg Psychiatry 2006 Oct 6 : Epub ahead of print (Impact factor:3.122)
64. Chin WW, Lau W, Ramaswamy B, Heng PW, Olivo M (2006) Chlorin e6 polyvinylpyrrolidone as a fluorescent marker for fluorescence diagnosis of human bladder cancer implanted on the chick chorioallantoic membrane model. Cancer Lett 245(1-2) : 127-33 (Impact factor:3.049)
65. Du Hy, Bay BH, Mahendran R, Olivo M (2006) Hypericin-mediated photodynamic therapy elicits differential interleukin-6 response in nasopharyngeal cancer. Cancer Lett 235(2) : 202-208 (Impact factor:3.049)
66. Pook SH, Toh CK, Mahendran R (2006) Combination of thiol antioxidant Silibinin with Brostallicin is associated with increase in the anti-apoptotic protein Bcl-2 and decrease in caspase 3 activity. Cancer Lett 238(1) : 146-152 (Impact factor:3.049)
67. Zhang C, Kong D, Tan MH, Pappas DL Jr, Wang PF, Chen J, Farber L, Zhang N, Koo HM, Weinreich M, Williams BO, Teh BT (2006) Parafibromin inhibits cancer cell growth and causes G1 phase arrest. Biochem Biophys Res Commun 350(1) : 17-24 (Impact factor:3)
68. Ho IA, Hui KM, Lam PY (2006) Targeting proliferating tumor cells via the transcriptional control of therapeutic genes. Cancer Gene Ther 13(1) : 44-52 (Impact factor:3)
69. Zhou Q, Bun Cheung Y, Rao Jada S, Teck Lim W, Kuo WL, Gray JW, Lee AS, Balram C (2006) EGFR Intron 1 Polymorphism in Asian Populations and its Correlation with EGFR Gene Expression and Amplification in Breast Tumor Tissues. Cancer Biol Ther 5(11) : 1445- 1449 (Impact factor:2.981)
70. Manivasager V, Yee KK, Heng PW, Soo KC, Olivo M (2006) A study comparing endogenous protoporphyrin IX induced by 5-ALA and ALA-methyl ester with exogenous PpIX and PpIX dimethyl ester in photodynamic diagnosis of human nasopharyngeal carcinoma xenografts. Int J Oncol 29(4) : 997-1002 (Impact factor:2.681)
71. Lee AT, Lee CG (200 ) Oncogenesis and transforming viruses: the hepatitis B virus and hepatocellularcarcinoma--the etiopathogenic link. Front Biosci 12 : 234-45 (Impact factor:2.623)
72. Gan SU, Kon OL, Calne RY (2006) Genetic engineering for haemophilia A. Expert Opin Biol Ther 6(10) : 1023-1030 (Impact factor:2.553)
73. Cheung YB, Goh C, Thumboo J, Khoo KS, Wee J (2006) Quality of life scores differed according to mode of administration in a review of three major oncology questionnaires. J Clin Epidemiol 59(2) : 185-191 (Impact factor:2.538)
74. Yip JL, Aung T, Wong TY, Machin D, Khaw PT, Khaw KT, Seah S, Foster PJ (2007) Socioeconomic status, systolic blood pressure and intraocular pressure: the Tanjong Pagar Study.. Br J Ophthalmol 91(1) : 56-61 (Impact factor:2.459)
75. Ha TC * Lyons-Wall PM, * Moore De, * Tattam BN, * Boyages J, * Ung OA, Ha TC., Lyons-Wall PM, Moore De, Tattam BN, Boyages J, Ung OA, Taylor RJ (2006) Phytoestrogens and indicators of breast cancer prognosis.. Nutr Cancer 56(1) : 3-10 (Impact factor:2.426)
76. Nolan WP, Aung T, Machin D, Khaw PT, Johnson GJ, Seah SK, Foster PJ (2006) Detection of narrow angles and established angle closure in Chinese residents of Singapore: potential screening tests. Am J Ophthalmol 141(5) : 896-901 (Impact factor:2.393)
77. Quek R, Lim ST, Ong S (2006) Hepatocellular carcinoma--Pathological complete response to oral capecitabine, megestrol and thalidomide. Acta Oncol 45(1) : 95-97 (Impact factor:2.362)
78. Woo E, Tan BK, Koong HN, Yeo A, Chan MY, Song C (2006) Use of the extended V-Y latissimus dorsi myocutaneous flap for chest wall reconstruction in locally advanced breast cancer.. Ann Thorac Surg 82(2): : 752-755 (Impact factor:2.229)
79. Goh BK, Tan YM, Lin SE, Chow PK, Cheah FK, Ooi LL, Wong WK (2006) CT in the preoperative diagnosis of fish bone perforation of the gastrointestinal tract. Am J Roentgenol 187(3) : 710-714 (Impact factor:2.209)
80. Yu Y, Kim HS, Chua HH, Lin CH, Sim SH, Lin D, Derr A, Engels R, DeShazer D, Birren B, Nierman WC, Tan P (2006) Genomic patterns of pathogen evolution revealed by comparison of Burkholderia pseudomallei, the causative agent of melioidosis, to avirulent Burkholderia thailandensis. BMC Microbiol 6 : 46 (Impact factor:2.176)
81. Toh CK, Lim WT (2006) Lung cancer in never-smokers. J Clin Pathol 2006 Aug 17 : Epub ahead of print (Impact factor:2.17)
82. Chin WW, Heng PW, Bhuvaneswari R Lau WK, Olivo M (2006) The potential application of chlorin e6-polyvinylpyrrolidone formulation in photodynamic therapy. Photochem Photobiol Sci 5(11) : 1031-1037 (Impact factor:2.147)
83. Saw CL, Olivo M, Soo KC, Heng PW (2006) Spectroscopic characterization and photobleaching kinetics of hypericin-N-methyl pyrrolidone formulations. Photochem Photobiol Sci 5(11) : 1018-1023 (Impact factor:2.147)
84. Low JS, Chua ET, Gao F, Wee JT (2006) Stereotactic radiosurgery plus intracavitary irradiation in the salvage of nasopharyngeal carcinoma. Head Neck 28(4) : 321-329 (Impact factor:1.975)
85. Tham IW, Lee KM, Yap SP, Loong SL (2006) Outcome of patients with nasal natural killer (NK)/T-cell lymphoma treated with radiotherapy, with or without chemotherapy. Head Neck 28(2) : 126-134 (Impact factor:1.975)
86. Goh BK, Tan YM, Cheow PC, Chung YF, Chow PK, Wong WK, Ooi LL (2006) Cystic lesions of the pancreas: an appraisal of an aggressive resectional policy adopted at a single institution during 15 years. Am J Surg 192(2) : 148-154 (Impact factor:1.924)
87. Goh BK, Tan HK (2006) Double pylorus. Am J Surg 191(4) : 515-516 (Impact factor:1.924)
88. Goh BK, Tan HK, Tan FL, Koong HN (2006) Epidural emphysema associated with spontaneous pneumomediastinum. Am J Surg 192(3) : 355-356 (Impact factor:1.924)
89. Goh BK, Tan YM, Chung YF, Chow PK, Ooi LL, Wong WK (2006) Retroperitoneal schwannoma. Am J Surg 192(1) : 14-18 (Impact factor:1.924)
90. Cheung YB, Daniel R, Ng GY (2006) Response and Non-response to a Quality-of-Life Question on Sexual Life: A Case Study of the Simple mean Imputation Method. Qual Life Res Epub ahead of print (Impact factor:1.915)
91. Ng KS, Tan AG, Chen KK, Wong SK, Tan HM (2006) CT features of primary epiploic appendagitis. Eur J Radiol Epub ahead of print (Impact factor:1.888)
92. Sia KC, Wang GY, Ho IA, Khor HY, Miao L, Hui KM, Lam PY (200 ) Optimal purification method for Herpes-based viral vectors that confers minimal cytotoxicity for systemic route of vector administration. J Virol Methods 139(2) : 166-74 (Impact factor:1.886)
93. Hum AY, Tan AS, Goh CR, Ju CA (2006) Hospice awareness in Singapore.. Palliat Med 20(3) : 221 (Impact factor:1.861)
94. Goh BK, Koong HN (2006) Massive traumatic extrapleural hematoma mimicking hemothorax: a potential pitfall of penetrating chest trauma. J Trauma. 61(4) : 995-997 (Impact factor:1.722)
95. Goh BK, Tan YM, Yap WM, Wong CY (2006) Hemorrhage into a pancreatic lymphangioma after blunt trauma mimicking a post-traumatic pancreatic pseudocyst. J Trauma 61(4) : 992-994 (Impact factor:1.722)
96. Goh BK, Koong HN (2006) Non-operative management of idiopathic segmental infarction of the greater omentum successfully diagnosed by computed tomography. J Gastroenterol Hepatol 21(10) : 1638-1639 (Impact factor:1.718)
97. Goh BK, Teo MC, Chng SP, Tan HW, Koong HN (2006) Upper gastrointestinal bleed secondary to duodenal metastasis: a rare complication of primary lung cancer. J Gastroenterol Hepatol 21(2) : 486-487 (Impact factor:1.718)
98. Goh BK, Tan YM, Chan WH, Yap CK, Ong HS, Wong WK (2006) Intra-abdominal lymphangioma: usefulness of endoscopic ultrasound and laparoscopy in diagnosis. J Gastroenterol Hepatol 21(1 Pt 2): : 340-341 (Impact factor:1.718)
99. Goh BK, Tan YM, Ooi LL (2006) Hepatobiliary and pancreatic: Cystic lymphangioma of the pancreas. J Gastroenterol Hepatol 21(3) : 618 (Impact factor:1.718)
100. Sun YJ, Lee ASG, Wong SY, Paton NI (2006) Association of Mycobacterium tuberculosis Beijing genotype with tuberculosis relapse in Singapore. Epidemiol Infect 134(2) : 329- 332 (Impact factor:1.674)
101. Jada SR, Hamzah AS, Lajis NH, Saad MS, Stevens MF, Stanslas J (2006) Semisynthesis and cytotoxic activities of andrographolide analogues. J Enzyme Inhib Med Chem 21(2) : 145- 155 (Impact factor:1.667)
102. Low WK, Gopal K, Goh LK, Fong KW (2006) Cochlear implantation in postirradiated ears: outcomes and challenges. Laryngoscope 116(7) : 1258-1262 (Impact factor:1.617)
103. Goh BK, Tan YM, Yap WM, Cheow PC, Chow PK, Chung YF, Wong WK, Ooi LL (2006) Pancreatic serous oligocystic adenomas: clinicopathologic features and a comparison with serous microcystic adenomas and mucinous cystic neoplasms. World J Surg 30(8) : 1553-1559 (Impact factor:1.601)
104. Goh BK, Tan YM, Chung YF, Chow PK, Cheow PC, Wong WK, Ooi LL (2006) A review of mucinous cystic neoplasms of the pancreas defined by ovarian-type stroma: clinicopathological features of 344 patients.. World J Surg 30(12) : 236-45 (Impact factor:1.601)
105. Goh BK, Quah HM, Chow PK, Tan KY, Tay KH, Eu KW, Ooi LL, Wong WK (2006) Predictive factors of malignancy in adults with intussusception. World J Surg 30(7) : 1300-1304 (Impact factor:1.601)
106. Teo M, Foo KF, Koo WH, Wong LT, Soo KC (2006) Lessons Learned from Initial Experience with Peritonectomy and Intra-peritoneal Chemotherapy Infusion. World J Surg 2006 Sep 7 : Epub ahead of print (Impact factor:1.601)
107. Goh BK, Chow PK, Quah HM, Ong HS, Eu KW, Ooi LL, Wong WK (2006) Perforation of the gastrointestinal tract secondary to ingestion of foreign bodies. World J Surg 30(3) : 372- 377 (Impact factor:1.601)
108. Thong PSP, Watt F, Ren MQ, Tan PH, Soo KC, Olivo M (2006) Hypericin-photodynamic therapy (PDT) using an alternative treatment regime suitable for multi-fraction PDT. J Photochem Photobiol B 82(1) : 1-8 (Impact factor:1.597)
109. Saw CL, Olivo M, Chin WW, Soo KC, Heng PW (2007) Superiority of N-methyl pyrrolidone over albumin with hypericin for fluorescence diagnosis of human bladder cancer cells implanted in the chick chorioallantoic membrane model.. J Photochem Photobiol B 86(3) : 207-18 (Impact factor:1.597)
110. Chin WW, Lau W, Heng PW, ramaswamy B, Olivo M (2006) Fluorescence imaging and phototoxicity effects of new formulation of chlorin e6-polyvinylpyrrolidone. J Photochem Photobiol B Mar 20 : Epub ahead of print (Impact factor:1.597)
111. Saw CL, Olivo M, Chin WW, Soo KC, Heng PW (2006) Superiority of N-methyl pyrrolidone over albumin with hypericin for fluorescence diagnosis of human bladder cancer cells implanted in the chick chorioallantoic membrane model. J Photochem Photobiol B 2006 Nov 27 : Epub ahead of print (Impact factor:1.597)
112. Chiu LQ, Lee DWS, Gao F, Ng GY, Toh CK (2006) Cancer patients’ preferences for communication of unfavorable news: an Asian perspective. Support Care Cancer 16 Feb 2006 : Epub ahead of print (Impact factor:1.59)
113. Chuah KL, Yap WM, Tan HW, Koong HN (2006) Recurrence of pulmonary acinic cell carcinoma. Arch Pathol Lab Med 130(7) : 932-933 (Impact factor:1.587)
114. Du HY, Li Y, Olivo M, Yip GW, Bay BH (2006) Differential up-regulation of metallothionein isoforms in well-differentiated nasopharyngeal cancer cells in vitro by photoactivated hypericin.. Oncol Rep 16(6) : 1397-402 (Impact factor:1.572)
115. Lim WT, Zhang WH, Miller CR, Watters JW, Gao F, Viswanathan A, Govindan R, McLeod HL (2007) PTEN and phosphorylated AKT expression and prognosis in early- and late-stage nonsmall cell lung cancer.. Oncol Rep 17(4) : 853-857 (Impact factor:1.572)
116. Goh BK, Ooi LL, Kumarasinghe MP, Tan YM, Cheow PC, Chow PK, Chung YF, Wong WK (2006) Clinicopathological Features of Patients with Concomitant Intraductal Papillary Mucinous Neoplasm of the Pancreas and Pancreatic Endocrine Neoplasm.. Pancreatology 6(6) : 520-526 (Impact factor:1.564)
117. Tan SB, Machin D (2006) Phase II trial designs in the presence of stratification. Stat Med 25(18) : 3220-3222 (Impact factor:1.477)
118. Tan SB, Machin D (2006) Bayesian two-stage designs for phase II clinical trials. Stat Med 25(19) : 3407-3408 (Impact factor:1.477)
119. Gao F, Chia KS, Krantz I, Nordin P, Machin D (2006) On the application of the von Mises distribution and angular regression methods to investigate the seasonality of disease onset. Stat Med 25(9) : 1593-1618 (Impact factor:1.477)
120. Loke YC, Tan SB, Cai Y, Machin D (2006) A Bayesian dose finding design for dual endpoint phase i trials. Stat Med 25(1) : 3-22 (Impact factor:1.477)
121. Pervaiz S, Olivo M (2006) Art and science of photodynamic therapy. Clin Exp Pharmcol P 33(5-6) : 551-556 (Impact factor:1.437)
122. Wong L, See HT, Khoo-Tan HS, Low JS, Ng WT, Low JJ (2006) Combined adjuvant cisplatin and ifosfamide chemotherapy and radiotherapy for malignant mixed mullerian tumors of the uterus. Int J Gynecol Cancer 16(3) : 1364-1369 (Impact factor:1.427)
123. See HT, Thomas DA, Bueso-Ramos C, Kavanagh J (2006) Secondary leukemia after treatment with paclitaxel and carboplatin in a patient with recurrent ovarian cancer. Int J Gynecol Cancer 16 Suppl 1 : 236-40 (Impact factor:1.427)
124. Tan CH, Chow PK, Thng CH, Chung AY, Wong WK (2006) Pancreatic adenocarcinoma that mimics groove pancreatitis: case report of a diagnostic dilemma. Digest Dis Sci 51(7) : 1294-1296 (Impact factor:1.388)
125. Tan KJ, Chow PK, Tan YM, Thng CH (2006) Portal vein thrombosis secondary to hyperhomocysteinemia: a case report. Digest Dis Sci 51(7) : 1218-1220 (Impact factor:1.388)
126. Goh BK, Tan YM, Kumarasinghe MP, Ooi LL (2006) Synchronous serous cystadenoma and pancreatic endocrine tumor: a case report and literature review. Digest Dis Sci 51(2) : 422-426 (Impact factor:1.388)
127. Goh BK, Chen JJ, Tan HK, Yong WS, Chan WH (2007) Acute variceal bleed in a patient with idiopathic myelofibrosis successfully treated with endoscopic variceal band ligation.. Dig Dis Sci 52(1) : 173-5 (Impact factor:1.388)
128. Lim ST, Fayad L, Tulpule A, Modiano M, Cabanillas F, Laffranchi B, Allievi C, Bernareggi A, Levine AM (2007) A phase I/II trial of pixantrone (BBR2778), methylprednisolone, cisplatin, and cytosine arabinoside (PSHAP) in relapsed/refractory aggressive non-Hodgkin’s lymphoma.. Leuk Lymphoma 48(2) : 374-80 (Impact factor:1.295)
129. Choo SP, Lim ST , Wong EH, Tao M (2006) Breast lymphoma: favorable prognosis after treatment with standard combination chemotherapy. Onkologie 29(1-2) : 14-18 (Impact factor:1.206)
130. Quek R, Ty A, Lim ST, See SJ, Wong MC, Yap SP, Sng I, Hee SW, Tao M (2006) Primary central nervous system lymphoma in an Asian population: a 15-year experience. Onkologie 29(10) : 455-459 (Impact factor:1.206)
131. Yoke PC, Tin GB, Kim MJ, Rajaseharan A, Ahmed S, Thongprasom K, Chaimusik M, Suresh S, Machin D, Bee WH, Seldrup J; Asian Lichen Planus Study Group (2006) A randomized controlled trial to compare steroid with cyclosporine for the topical treatment of oral lichen planus. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 102(1) : 47-55 (Impact factor:1.193)
132. Thong PSP, Watt F, Ren MQ, Soo KC, Olivo M (2006) Investigating the role of calcium and biological trace elements in hypericin photodynamic therapy induced tumor cell death using nuclear microscopy. Nuclear Instr and Meth B 231 : 315-320 (Impact factor:1.181)
133. Choo SP, Kong KH, Lim WT, Gao F, Chua K, Leong SS (2006) Electroacupuncture for refractory acute emesis caused by chemotherapy. J Altern Complement Med 12(10) : 963-9 (Impact factor:1.051)
134. Wu B, Wang M, Wang JG, Pan L, Hui KM (2006) Establishment of a discriminant mathematical model for diagnosis of deficiency-cold syndrome using gene expression profiling. J Altern Complement Med 12(8) : 751-761 (Impact factor:1.051)
135. Teo He, Peh WC, Akhilesh M, Tan SB, Ishida T (2006) Congenital osteofibrous dysplasia associated with pseudoarthrosis of the tibia and fibula. Skeletal Radiol 2006 Aug 30 : Epub ahead of print (Impact factor:0.98)
136. Lee JS, Pei-Lin Ng P, Tao M, Lim WT (2006) Paraneoplastic pemphigus resembling linear IgA bullous dermatosis. Int J Dermatol 45(9) : 1093-1095 (Impact factor:0.942)
137. Goh BK, Ang P, Wu YJ, Goh CL (2006) Characteristics of basal cell carcinoma amongst Asians in Singapore and a comparison between completely and incompletely excised tumors. Int J Dermatol 45(5) : 561-564 (Impact factor:0.942)
138. Zhou JY, Chong VF, Khoo JB, Chan KL, Huang J (2007) The relationship between nasopharyngeal carcinoma tumor volume and TNM T-classification: a quantitative analysis. Eur Arch Otorhinolaryngol 264(2) : 169-174 (Impact factor:0.895)
139. Teo MC, Tan YM, Hee SW, Chung YF, Chow KH, Cheow PC, Soo KC, Ooi PJ (2006) Metastectomy for non-colorectal, non-neuroendocrine liver secondaries. ANZ J Surg 76(7) : 575-578 (Impact factor:0.783)
140. Tan FL, Tan YM, Chung AY, Cheow PC, Chow PK, Ooi LL (2006) Factors affecting early mortality in spontaneous rupture of hepatocellular carcinoma. ANZ J Surg 76(6) : 448-452 (Impact factor:0.783)
141. Woon CY, Tan YM, Oei CL, Chung AY, Chow PK, Ooi LL (2006) Adult choledochal cysts: an audit of surgical management. ANZ J Surg 76(11) : 981-986 (Impact factor:0.783)
142. Goh BP, Tan YM, Chung YF, Chow PH, Ong HS, Lim DH, Wong WK, Ooi LP (2006) Non-neoplastic cystic and cystic-like lesions of the pancreas: may mimic pancreatic cystic neoplasms. ANZ J Surg 76(5) : 325-331 (Impact factor:0.783)
143. Tan EY, Hoon TP, Yong WS, Wong HB, Hui HG, Yeo AW, Wong CY (2006) Recurrent phyllodes tumours of the breast: pathological features and clinical implications. ANZ J Surg 76(6) : 476-480 (Impact factor:0.783)
144. Pan L, Wang M, Wang JG, Wu B, Hui KM (2006) Clinical and molecular evaluation of warming and tonic herb treatment for sibling patients of a typical kidney-yang deficiency family. Am J Chin Med. 34(3) : 387-400 (Impact factor:0.743)
145. Toh HC (2006), Public healthcare--welfare, market share or laissez-faire?--a Sentosa Carlsberg skytower view. Ann Acad Med Singapore 35(2) : 119-122 (Impact factor:0.419)
146. Low SC, Lo RH, Lau TN, Ooi LL, Ho CK, Tan BS, Chung AY, Koo WH, Chow PK (2006) Image-guided radiofrequency ablation of liver malignancies: experience at Singapore General Hospital.. Ann Acad Med Singapore 35(12) : 851-857 (Impact factor:0.419)
147. Ha TC, Tan SB, Soo KC (2006) The journal impact factor: too much of an impact?. Ann Acad Med Singapore 35(12) : 911-6 (Impact factor:0.419)
148. Lee VT, Chung AY, Chow PK, Thng CH, Low AS, Ooi LL, Wong WK (2006) Infected pancreatic necrosis--an evaluation of the timing and technique of necrosectomy in a Southeast Asian population. Ann Acad Med Singapore 35(8) : 523-530 (Impact factor:0.419)
149. Poon D, Foo KF, Chew L, Leong SS, Wee J, Tan EH (2006) Phase II Trial of Gemcitabine and Cisplatin Sequentially Administered in Asian Patients With Unresectable or Metastatic Non-small Cell Lung Cancer. Ann Acad Med Singapore 35(1) : 33-35 (Impact factor:0.419)
150. Tan FL, Tan YM, Heah SM, Seow-Choen F (2006) Adult Hirschsprung’s disease presenting as sigmoid volvulus: a case report and review of literature. Tech Coloproctol 10(3) : 245- 248
151. Chao VT, Lim DW, Tao M, Thirugnanam A, Koong Hn, Lim CH (2006) Tracheobronchial obstruction as a result of mediastinal mass. Asian Cardiovasc Thorac Ann 14(2) : e17-18
152. Kah JCY, Sheppard CJR, Lee CGL, Olivo M (2006) Application of Antibody-Conjugated Gold Nanoparticles for Optical Molecular Imaging of Epithelial Carcinoma Cells. Proc SPIE 6095 : 1-6
153. Ho KY, Cheng J, Wee A, Soo KC (2007) Primary malignant melanoma of the esophagus with multiple esophageal lesions.. Nat Clin Pract Gastroenterol Hepatol 4(3) : 171-174
154. Wan WH, Tan KY, Ng C, Tay KH, Mancer K, Tay MH, Chia WK, Soo KC, Ooi LL (2006) Metastatic Malignant Phaeochromocytoma: A Rare Entity that Underlies a Therapeutic Quandary. Asian J Surg 29(4) : 294-302
155. Wee HL, Li SC, Xie F, Zhang XH, Luo N, Cheung YB, Machin D, Fong KY, Thumboo J (2006) Are Asians comfortable with discussing death in health valuation studies? A study in multi-ethnic Singapore.. Health Qual Life Outcomes 4 : 93
156. Sabapathy K (2006) Chapter 3 - Physiological role of the different JNKs – lessons from the JNK knockouts. JNK signaling; Edited by A. Lin. Landes BioSciences Chapter 3 : 29-39
157. Tan P (2006) Cancer therapy: molecular targets in tumor-host interactions. Singapore Med J 47(2) : 175-176
158. Zheng W, Olivo M, Kho KW, Thong P, Harris M, Soo KC (2006) Confocal fluorescence endomicroscopic imaging of the tongue. SPIE – Photonics West 5686 : 301-306
159. Seet E, Leong WL, Yeo AS, Fook-Chong S (2006) Effectiveness of 3-in-1 continuous femoral block of differing concentrations compared to patient controlled intravenous morphine for post total knee arthroplasty analgesia and knee rehabilitation. Anaesth Intensive Care 34(1) : 25-30
160. Olivo M, Chin W (2006) Perylenequinones in Photodynamic Therapy: Cellular versus Vascular Response. J Environ Pathol Toxicol Oncol 25(1-2) : 223-238
161. Chen HM, Tan WH, Tan WC, Yu CK, Lim TH, Tay MH, See HT (2006) Attitudes towards cancer survivors: a small survey. Singapore Med J. 47(2) : 143-146
162. Kho KW, Olivo M, Shen ZX, Soo KC (2006) Surface enhanced Raman spectroscopic (SERS) study of saliva in the early detection of oral cancer. SPIE-BIOS 5702 : 84-91
163. Lee Sy, Sin YK, Kurup A, Agasthian T, Caleb MG (2006) Stent-graft for Recurrent Melioidosis Mycotic Aortic Aneurysm. Asian Cardiovasc Thorac Ann 14(2) : e38-40


 

 

 
 
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