What is cancer?
Meet Lizzy the liver cell
What causes cancer?
How is cancer detected?
How is cancer treated?
Trends in cancer incident in Singapore
ABC glossary of cancer terms

 

ABCs of Cancer
 

Genes

When the `brakes' of a cell is out of order
 

Scientists have discovered that some cells have a natural tendency to become cancerous on their own because they contain certain genes that could cause cancer.

Some cells are normal at first because they contain genes called Tumour-suppressor genes. They stop cells from growing abnormally into a tumour. When these Tumour suppressor genes are inactivated or destroyed completely by carcinogens, they lose their `braking power' and allow the cells to divide abnormally instead of stopping them.

Other cells have genes called Oncogenes (onco- means `cancer'). In a normal cell, these oncogenes help to regulate normal cell growth. They change their behaviour when exposed to radiation and chemicals and mutate, so becoming genes that stimulate excessive division. This situation is similar to moving car with the accelerator pressed to the maximum!